Many of us haven’t been sick in over a year due to lack of exposure to germs (COVID stay at home etc). Does this create any risk for our immune systems in the coming years? | AskScience Blog

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Thursday, April 1, 2021

Many of us haven’t been sick in over a year due to lack of exposure to germs (COVID stay at home etc). Does this create any risk for our immune systems in the coming years?

Many of us haven’t been sick in over a year due to lack of exposure to germs (COVID stay at home etc). Does this create any risk for our immune systems in the coming years?


Many of us haven’t been sick in over a year due to lack of exposure to germs (COVID stay at home etc). Does this create any risk for our immune systems in the coming years?

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Why vaccine dosages are not related to body weight?

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Last Sunday i finally got my first Astrazeneca shot, it went very smooth, almost no side effects, but many of my fellow university students that also got it complained about some pretty harsh stuff, some of them have been sick for as long as 5 days.

One thing i noticed though is that apparently women suffered the most, and i wondered could body weight play a difference?

I weigh a little more than 100 kg, and most of the women i know that suffered side effects weigh from 55 to 65 kg. So since the dosage is the same, could it be more potent the smaller the body weight? I mean, usually medications are dosed based on body weight, why vaccines aren't?

submitted by /u/DrLimp
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For an mRNA vaccine with a viral vector (such as the AstraZeneca Covid-19 vaccine) how exactly do they remove the virus' native genetic material and get the desired RNA inside it?

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What, if any, are the longterm effects of hypothermia and frostbite?

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While I have found plenty of results about short-term damage like swelling and necrotic tissue, I can't find anything regarding long-term damage that could arise, like skin damage or cracked skin.

Yet, media will sometimes leave patches of blue skin on hypothermia survivors. Is this just a fictional trope?

submitted by /u/ECarnival
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“Every outcome has a 50% chance of happening.” — Is there an explanation to why this is or isn’t a true statement? Is this a paradox?

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Q: There are three marbles in a jar: red, yellow, and green. What are the chances you pull out the red marble?

A: 50%. You either do or do not pull out the red marble.

Q: You're swimming in the ocean. What are the chances you get eaten by a shark?

A: 50%. You either do or do not get eaten by a shark.

Q: What are the chances the Sun burns out tomorrow?

A: 50%. The Sun either does or does not burn out tomorrow.


Are these statements true? If they are false, why? Is there a difference between determining whether they are true or false by using math vs logic? Is this a paradox?

submitted by /u/InevitablyWritten
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Will a person have already produced covid antibodies 24 hours after their first vaccine?

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Why are patients given the same amount of vaccine/medicine regardless of their weight?

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Wouldn't it make sense to give smaller people less medicine than bigger ones?

submitted by /u/karlheinzweidrei
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Are EM waves limited to a single 2D plane?

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Are all EM waves 2 dimensional? In textbooks you usually only see a 2d representation. Do waves oscillate left and right and up and down? Are they more like spirals? Is the plane fixed? What determines the plane in the first place?

submitted by /u/zakalewes
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If you donate blood 24 hours after getting a covid vaccine should that affect the level of immunity you acquire at all?

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Individuals in the Southern Hemisphere may be taking the standard flu vaccine currently, is there a waiting period for the covid shot before they can take it?

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For example in the Southern Hemisphere.. if full public roll out has not occurred yet and the essential workers are getting vaccinated currently. Some individuals at risk may take the normal flu shot (for flu protection, not for covid itself obviously).. Is there a waiting period before they could possibly take the covid-19 vaccine? Just curious.

Edit: word stuff

submitted by /u/Weep2D2
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How do common, chronically administered antivirals, such as acyclovir, not interfere with the efficacy of viral vector vaccines? Is it the mechanism/specificity of the antiviral, the behavior of the viral vector, or a combination of both?

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can you get covid from a misquito bite?

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What is the state of science on wastewater viral load tests for COVID and their relationship to positive PCR test results? Specifically interested in latency between symptomatic and infectious stages and sample collection dates.

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Hi all, long time reader, 1st time asker.

Companies like Biobot offer sewage testing options for determining viral concentration per unit volume, accounting for total flow volume in a system and determining the number of possible cases expected a result. While that specific claim doesn't seem to be terribly robust, viral load data does appear to have some relevant value in establishing other metrics for epidemiological surveillance. Are there any useful, relevant or especially noteworthy studies that help establish what specific information can be inferred from sewage testing? Or, more ideally, something written for a non specialist (IANAB) with a current state of the art on this subject. I've tagged this COVID as I thought it most relevant, but if there are non-COVID studies related to this subject, I would also be interested in those.

I apologize if this is a bit vague.

submitted by /u/supercalifragilism
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What actually happens in your throat when it gets sore from shouting or speaking loudly too much?

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So when you shout cause of high background noise like a gig or around machinery your throat gets a tickle in it after a while. Whats happening here?

submitted by /u/bastardisedmouseman
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What's the 'strong adjuvant' in "mRNA vaccines take on immune tolerance"?

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https://www.nature.com/articles/s41587-021-00880-0

This looks like a very promising bit of technology but (from my lay point of view) it glosses over the most important part: the adjuvant used. If I'm reading it right, if you deliver the immunization without the adjuvant, the immune response increases; with the adjuvant, it suppresses. So the exact nature of the adjuvant seems kinda important.

submitted by /u/yerfdogyrag
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