A credible SARS-NCOV vaccine manufacturer said large scale trials shows 90% efficiency. Is the vaccine ready(!)? | AskScience Blog

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Tuesday, November 10, 2020

A credible SARS-NCOV vaccine manufacturer said large scale trials shows 90% efficiency. Is the vaccine ready(!)?

A credible SARS-NCOV vaccine manufacturer said large scale trials shows 90% efficiency. Is the vaccine ready(!)?


A credible SARS-NCOV vaccine manufacturer said large scale trials shows 90% efficiency. Is the vaccine ready(!)?

Posted: 09 Nov 2020 10:03 AM PST

Apparently the requirements by EU authorities are less strict thanks to the outbreak. Is this (or any) vaccine considered "ready"?

Are there more tests to be done? Any research left, like how to effectively mass produce it? Or is the vaccine basically ready to produce?

submitted by /u/Marc_A_Teleki
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What is happening in our mind when we figure a solution to a problem?

Posted: 10 Nov 2020 01:21 AM PST

What exactly happens, so that a moment before we did not have an answer but after a really brief time we somehow know the answer?

submitted by /u/kettuhfdg
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How do we know how long nuclear waste stays dangerous?

Posted: 10 Nov 2020 06:12 AM PST

Let me start off by saying I don't know what flair this fits under. Now let's start with the actual qeustion.

I've been looking into nuclear powerplants and nuclear energy recently. I saw alot of posts about radioactive waste staying dangerous for over a thousand years.

How do we roughly know how long this waste stays dangerous for? We haven't been using nuclear energy for thousands/hundreds of years. How are these calculations made?

submitted by /u/IKEASTOEL
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How to calculate the error in a constant when using curve fitting?

Posted: 10 Nov 2020 07:13 AM PST

Hi, I'm using curve fitting to calculate a constant b. The curve has the equation:

y = (0-a) * exp(-b*x) + a

I have measurements for y (with errors) and measurements of x (also with errors). How do i calculate the error in a and b?

I'm using Scipy for the curve fitting that returns the covariance matrix, the documentation says that a standard deviation can be computed using the square route of the diagonal.

perr = np.sqrt(np.diag(pcov))

is this giving me the standard deviation for a and b?

I have to use b in another equation ln(b) = mx+c

This document suggests that the standard deviation of x = ln(b) is the ratio of standard deviation to calculated value. Is this correct?

The value for x is precisely measured (enough to be considered constant) how do i figure out the error in m?

Thanks for having a look at this. I've been banging my head against a wall trying to put some error bars on the ln(b) = mx + c graph but i haven't done error propagation in 10 years or more.

submitted by /u/Deemonfire
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When an electron passes through something via quantum tunneling, how do we know it is the same electron that reemerges on the other side?

Posted: 10 Nov 2020 08:33 AM PST

Could one electron be eliminated from the universe and a brand new one pop into existence, or is the same physical electron actually preserved through the "tunnel"?

submitted by /u/Robertdigitalorgasm
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Can someone help me get over my curiosity?? - Seafloor Spreading

Posted: 10 Nov 2020 01:05 AM PST

Hey guys, I have been curious for a long time and I hope once I post this I finally get the answers I want.

  1. Why is seafloor spreading more acceptable rather than the continental drift hypothesis?

  2. What were the loopholes or errors in the seafloor spreading study?

Thanks to whoever answers these, I can't find any reliable or viewable source online.

submitted by /u/braintyp
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How are minor plates formed?

Posted: 10 Nov 2020 03:14 AM PST

I tried to search about this everywhere but I can't find an answer for it, so I hopped onto this subreddit hoping I can find one here. So, how are minor plates formed?

submitted by /u/Shake_Fabulous
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What % of effectiveness is the flu shot?

Posted: 09 Nov 2020 04:45 PM PST

I have a bunch of noob questions on star formations. Please help answer?

Posted: 09 Nov 2020 10:13 PM PST

So I'm learning about how stars are formed, and the incredibly varied types of stars. It's amazing! but I don't understand a few things:

  • If a white dwarf can have the same mass as our sun, why would it condense into the size of our earth?
  • Alternately, if our sun contains the mass of a white dwarf, why isn't our sun a white dwarf?
  • When a star sheds its outer layer (like an event where an iron core collapses in on itself), what exactly does it mean, "it's outer core"?
  • When our sun matures, becomes a red dwarf, then eventually explodes into a planetary nebula, I'm assuming a new star will be formed along with new planets. What kind of star will form? Can there be more than one star that forms?
  • What is the essential difference that determines the birth of a stellar nebula vs a planetary nebula?

Thank you all for furthering my education.

submitted by /u/gomi-panda
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Has the Covid pandemic reduced the average life expectancy in hard-hit countries, even just the annual average?

Posted: 09 Nov 2020 07:43 AM PST

I'm not sure how life expectancy is calculated or exactly how to phrase this question.

If we were to look at a map charting life expectancy over time, would we see a sudden dip in 2020 due to the pandemic? Or does an event like this not have much bearing on the calculation of life expectancy?

If it does have an effect, what would be the decrease in years for the population average? For instance, if life expectancy in the US was, say, 79 in 2019, is it 77.4 in 2020?

submitted by /u/cohonka
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Since the mRNA vaccine targets SARS-CoV-2's spike protein, does this mean it could be effective for other diseases caused by coronaviruses?

Posted: 10 Nov 2020 05:11 AM PST

Would this also be a vaccine for SARS-CoV-1 or other Coronaviruses? Or is SARS-CoV-2's spike protein unique?

submitted by /u/jahvidsanders44
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Anyone know what they are using in the placebo arm of the Pfizer / BNT 162 phase III trials?

Posted: 10 Nov 2020 04:51 AM PST

Had a look on clinicaltrials.gov but could only see 'an intramuscular injection' specified.

submitted by /u/dancingn1nja
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Differences between the Pfizer/BioNTech vaccine and Sputnik V?

Posted: 10 Nov 2020 12:46 AM PST

Yesterday's news seem to have given everyone a much-needed dose of optimism. Understandably, when Russia announced its own COVID vaccine a few months back, the reaction was much less enthusiastic. I'm from Moscow, and, although anecdotal, don't know a single person who is planning to inject Sputnik V, primarily due to a deep lack of trust in our government and everything related. Russians, for the most part, don't think it's safe, or at least that it's too early to say.

Now, I know very little about the actual science behind these vaccines. With the information we currently have, is it possible to compare the two? Do they operate on the same principle, or are they inherently different? I have a feeling that for most Russians, Sputnik V will be the default/only option for some time, so would really like to know if what we're getting is in at least the same ballpark as the supposedly world-saving BioNTech vaccine. Greatly appreciate any info.

submitted by /u/kostya8
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What causes high temperature superconductivity? Is it possible to make a material that is a superconductor at room temperature?

Posted: 09 Nov 2020 12:26 PM PST

Are multiple vaccines more effective than one vaccine?

Posted: 09 Nov 2020 05:22 PM PST

If we end up having 3-5 effective vaccines in use simultaneously, would their combined efficacy be greater than or less than having the same number of doses of a single vaccine type? Does having a variety of vaccines safeguard against mutation, or provide opportunities for mutations to take hold?

submitted by /u/o_shrub
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Are you contagious directly following Flue Vaccination?

Posted: 10 Nov 2020 02:10 AM PST

Hi!

I got the flue vaccine yesterday and started presenting fever symptoms later that day. I'm currently living with someone undergoing cancer-treatment and have thus isolated myself.

How (if at all) contagious is a person in my position?

submitted by /u/Cndymountain
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Is the mink mutation in Covid19 serious? And how bad is it?

Posted: 09 Nov 2020 12:54 PM PST

Can an mRNA vaccine cause the immune system to attack the cell expressing an antigen?

Posted: 09 Nov 2020 12:13 PM PST

I'm aware that mRNA vaccines will cause cells to express an antigen of interest, like one for COVID, and cause the immune system to produce antibodies for a disease. But couldn't that also cause the immune system to attack the very cell expressing the antigen?

submitted by /u/kabow94
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How or why do "inactivated" - aka dead bacterial probiotics work?

Posted: 09 Nov 2020 06:44 AM PST

I've bought probiotics for my stomache that contain a patented strain of bacteria. This particular medication has been studied extensively and has been proven to be around 25% more effective than placebo in treating specific stomach issues. The issue is, the bacteria contained has been inactived by heat, so they're dead. How does dead bacteria have a positive impact on my gut? Thanks :-)

submitted by /u/Bavarian0
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Why does the first COVID-19 vaccine need you to take two doses weeks apart?

Posted: 09 Nov 2020 12:32 PM PST

Per this the first successful COVID-19 vaccine has been found, but it requires you to take two doses three weeks apart.

Why? Is it because taking one dose of twice the size would be unsafe, or is there some biological reason why the later dose is more effective after a delay?

submitted by /u/sciencecritical
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Is the Sun's gravitational pull on the Moon weaker or stronger than the Earth's one?

Posted: 09 Nov 2020 01:56 PM PST

How is the flow data of a river and its tributaries calculated? And is there a way to predict river levels accurately if it has been raining in that particular rivers catchment?

Posted: 09 Nov 2020 10:11 PM PST

Vaccines and the immune response?

Posted: 10 Nov 2020 01:48 AM PST

According to what I have read, vaccines introduce a weakened or dead part of a virus. So there is no risk of contracting the actual virus, however the external agent does trigger an immune response in the body, and in some cases it can lead to mild fever.

My question is, for someone vulnerable, could this mild fever turn into a more serious high fever or even a life-threatening complication?

In my country, it was recommended that older people don't take flu vaccines as usually anymore. But I don't know if the reason for this is because they already have a good immunological system or because their immunological system is to weak to adapt to an external agent and would put their lives at risk.

submitted by /u/LevyathanBoi
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