Why do doctors bother with painkillers like oxycodon, etc, that barely differ from morphine? |
- Why do doctors bother with painkillers like oxycodon, etc, that barely differ from morphine?
- What makes a particle radioactive?
- Does an equation exist which is used to calculate the melting temperature of compounds?
- If John Dalton's model of the atom was wrong, how do we know Rutherford's model right?
- How ubiquitous are drugs in the ambient atmosphere?
- If electrically charged particles were fired into a black hole, what would happen? Would there be a point at which the electro-static repulsion of the particles overcame the force of gravity?
- What is the ultimate destination of the voyager probe and has it been calculated where it will inevitably end up if it continues on its current trajectory?
- Why does DNA pack itself into Chromosomes for replication and how/what makes it know to do so?
- How does CO2 have such a dramatic impact on thermal insulation, despite comprising less that 0.5% of the atmosphere?
- How do archaeologists/anthropologists determine the sex of human remains (not limited just to skeletons)?
- What coordinate system do various space missions use? Are different ones used for different missions (e.g. centered on Earth and rotating, centered on the Sun and stationary, etc)?
- How representative/accurate are the samples in the surveys of Americans' opinions? Is it really possible to say with any level of certainty that xx% of Americans feel one way or the other?
- Does the body convert macronutrients into other macronutrients?
- What causes swelling from injuries with humans?
- Are there any other snow-like substances?
- How do transparent TVs display "black"?
- Why does Carbon-14 have a longer half life than Carbon-10?
- Are there known solar systems with planets NOT all orbiting in the same plane?
- How can an evanescent wave be attenuated if it carries no energy?
- Very bright star or more?
- Why is sativa so commonly used in plant names?
| Why do doctors bother with painkillers like oxycodon, etc, that barely differ from morphine? Posted: 06 Jan 2017 11:32 PM PST Specifically what I'm asking is why bother having so many different strong opiates if they all have very, very similar profiles? Besides duration, and the ceiling of the painkilling effects (i.e. codeine vs. morphine), the differences are very slight between these drugs. In fact I believe only morphine makes the WHO's list of essential medicines for a healthcare system. Why bother stocking all the rest? Edit:To add to this, I'm mostly interested in what, if any, implications the often slight alterations in morphine's analogues have that make them more desirable than morphine itself. Primarily I'm interested in how these small changes effect a drug's structure-activity relationship. Opiates are really just an ideal example I picked, if you know something regarding this in other kinds of drugs, that's also of help. I am aware of the following points: Pharma pressures doctors to use new but not very innovative products, and that doctors like to rotate a person's pain medication to reduce tolerance effects. [link] [comments]  |
| What makes a particle radioactive? Posted: 07 Jan 2017 02:28 AM PST |
| Does an equation exist which is used to calculate the melting temperature of compounds? Posted: 06 Jan 2017 07:54 PM PST Does an equation exist which is used to calculate the melting temperature of compounds? Research tells me that melting temperature is determined by the ion and covalent bonding, but that was all that I could find. If there is such an equation, could you please provide a link to the source to confirm? Thanks in advance for any guidance. This is needed for the production of a prototype for a new type of battery cathode. [link] [comments]  |
| If John Dalton's model of the atom was wrong, how do we know Rutherford's model right? Posted: 06 Jan 2017 05:39 PM PST |
| How ubiquitous are drugs in the ambient atmosphere? Posted: 06 Jan 2017 06:58 PM PST So I've read that researchers detected drugs from caffeine to cocaine in the ambient atmosphere in some major cities like Rome. I want to know: how far can they spread? If I live in the suburbs, am I technically consuming a few molecules of caffeine or nicotine every time I breath? What about out in the country? Do drugs in the air end up in rain water? [link] [comments]  |
| Posted: 06 Jan 2017 11:58 AM PST |
| Posted: 07 Jan 2017 01:28 AM PST |
| Why does DNA pack itself into Chromosomes for replication and how/what makes it know to do so? Posted: 06 Jan 2017 12:34 PM PST Hi all!
Hope this question makes sense, been doing some self-study on this and can sort of understand the process of DNA packing into Chromosomes and that it's to make it smaller and easier to transfer (I think, is the main reason). But what really gets me is how does it know to do this? Did it try to do it without packing in the past and evolution decided it was a bad idea?
Hope someone is able to give me a bit of a hand with this, as has quite stumped me. Thanks for any answers!
p.s. I have a load of other smallish questions if anyone in genetics would be happy for me to ask them personally some questions, as I feel bad making posts for what could be simple questions, please let me know as it would be a great help :) [link] [comments]  |
| Posted: 06 Jan 2017 01:21 PM PST Heard this counter argument against global warming the other day, and it made me wonder [link] [comments]  |
| Posted: 06 Jan 2017 02:19 PM PST Also, presuming there are different methods, how relatively reliable are different methods? Also, if there is a mismatch between the presumed sex of bodily remains and the presumed gender signaled by any burial goods found with the remains, how is this usually interpreted? [link] [comments]  |
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| Does the body convert macronutrients into other macronutrients? Posted: 06 Jan 2017 08:32 PM PST So my friends and I had a discussion. They think that the human body can convert carbs and proteins into fats and pretty much all of them into each others. While I agree that you can get "fat" by eating too much carbs and proteins ( because of the calories) I have to disagree that the body can really convert those into others. I see it as your body needs those three macronutrients to survive and body fat is an entirely different fat from the macronutrient. I hope you can help us. [link] [comments]  |
| What causes swelling from injuries with humans? Posted: 06 Jan 2017 06:45 PM PST Why does the body cause swelling, sometimes some more massive than others when we receive particular types of injuries? I.e. sprains/breaks/fractures. Why does the body cause such a discomfort? How does this help us? [link] [comments]  |
| Are there any other snow-like substances? Posted: 06 Jan 2017 07:58 AM PST Are there any other elements, molecules, compounds, etc. that naturally form crystalline structures similar to snow? Like, if we were to visit a planet with a different composition could it possibly have methane snow or nitrogen snow or something? If so, what would it be like? Would it be a different color? Bigger or smaller flakes? Unstable in some way? Useful for anything? Just curious, and wondering what blue or orange snow would look like. [link] [comments]  |
| How do transparent TVs display "black"? Posted: 06 Jan 2017 09:38 AM PST Seen here: https://youtu.be/MvEaGB42EjE In a phone for example, the default screen is black, so to display black, just shut off the pixels, this makes sense to me. But how can a piece of glass add light to create something darker than it is? I know how stupid my wording sounds and trust me i will also post on /r/ nostupidquestions. This has actually been bothering me for quite a while. [link] [comments]  |
| Why does Carbon-14 have a longer half life than Carbon-10? Posted: 06 Jan 2017 05:25 AM PST If the two were positron emitters, why would Carbon-10 have a shorter half-life? They are both equally distant from stability, I can't seem to find a good answer. [link] [comments]  |
| Are there known solar systems with planets NOT all orbiting in the same plane? Posted: 06 Jan 2017 05:40 AM PST I could find that the planets in our own solar system all orbit in the same plane due to how the solar system was formed. Is this the only possibility or would it be possible for the planets to orbit in let's say, 2 planes? [link] [comments]  |
| How can an evanescent wave be attenuated if it carries no energy? Posted: 06 Jan 2017 06:18 AM PST I was reading this description of ATR in IR-spectroscopy but I have a hard time understanding how the absorption is actually measured. [link] [comments]  |
| Posted: 06 Jan 2017 05:55 PM PST I live in the NW near Mt. Hood, as I'm walking my dog, I noticed a very bright star, South West of mars(to the 5 o'clock). What is it? It's much brighter than Mars but much smaller the moon. I couldn't tell if it was moving but it was definitely abnormally bright. Anyone know what it could be? [link] [comments]  |
| Why is sativa so commonly used in plant names? Posted: 06 Jan 2017 09:41 AM PST I'm curious why sativa is so common such as in cannabis sativa and oryza sativa etc. [link] [comments]  |
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