Why can't we use live SARS-CoV-2 as a Covid-19 vaccine? |
- Why can't we use live SARS-CoV-2 as a Covid-19 vaccine?
- What kind of treatment would someone with schizophrenia have received in the early 70s?
- Theoretically, if the whole world isolates itself for a month, could the flu, it's various strains, and future mutated strains be a thing of the past? Like, can we kill two birds with one stone?
- Ask Anything Wednesday - Engineering, Mathematics, Computer Science
- Is there a difference between sleeping late or sleep early if you still get the recommended hours?
- Would administering an inactive mimic of the SARS-COVID-2 binding site on ACE2 competitively inhibit virus entry into cells?
- Why we can make plasma with a microwave if it uses non-ionizing frequencies?
- What are the most promising COVID vaccine efforts and are there any easy fixable bottlenecks (like funding) holding them back?
- Why did the Spanish flu of 1918 spread at a similar rate as Covid19, despite vastly inferior international travel at that time?
- What causes some viruses to stay for life (such as HIV or Herpes) but other viruses (such as influenza) can be fought off by the body?
- How and when do ants decide that it is time to stop building the anthill?
- If you observed light being emitted from a source which incrementally increased the wavelength by 1nm. When that light starts to transition from visible to UV light, would there be a specific wavelength where we would suddenly stop perceiving anything or would it be more of a gradual fading out?
- Why are African Americans in the US dying of COVID-19 at higher rates than those of other ethnicities?
- What the composition difference of body shampoo and hair shampoo? Can one be used to substitute one another?
- Why do birds move their heads like stop motion animation? Why don't they have more fluid head movements?
- How do various flu vaccines get regularly tested and produced each year to account for mutation?
- If I use distortion goggles for a week or 2 until my brain gets used to it, would my brain have difficulty adjusting to the "old world" once I take off the goggles?
- What is the risk that Covid-19 mutates into a mosquitoe-borne viral infection?
- Why aren’t monoclonal antibodies used for more drugs/vaccines?
- How will social distancing and shelter at home practices effect diseases other than Covid-19?
- From seeing the supermoon tonight it made me curious, is there ever a night with no moon?
- Why are fires around Chernobyl increasing radiation levels?
| Why can't we use live SARS-CoV-2 as a Covid-19 vaccine? Posted: 07 Apr 2020 04:13 PM PDT The SARS-CoV-2 virus infects the upper and lower respiratory tract in humans. As far as I understand, it does not infect other parts of the body, e.g. muscle tissue. So I would expect that if the virus is injected into muscle tissue, it should help the recipient develop immunity, which could then protect them from a conventional Covid-19 infection. This is not being done, so either:
Is any of the above the right answer? Or is it something else entirely? [link] [comments]  |
| What kind of treatment would someone with schizophrenia have received in the early 70s? Posted: 08 Apr 2020 05:09 AM PDT |
| Posted: 08 Apr 2020 02:27 AM PDT |
| Ask Anything Wednesday - Engineering, Mathematics, Computer Science Posted: 08 Apr 2020 08:09 AM PDT Welcome to our weekly feature, Ask Anything Wednesday - this week we are focusing on Engineering, Mathematics, Computer Science Do you have a question within these topics you weren't sure was worth submitting? Is something a bit too speculative for a typical /r/AskScience post? No question is too big or small for AAW. In this thread you can ask any science-related question! Things like: "What would happen if...", "How will the future...", "If all the rules for 'X' were different...", "Why does my...". Asking Questions: Please post your question as a top-level response to this, and our team of panellists will be here to answer and discuss your questions. The other topic areas will appear in future Ask Anything Wednesdays, so if you have other questions not covered by this weeks theme please either hold on to it until those topics come around, or go and post over in our sister subreddit /r/AskScienceDiscussion , where every day is Ask Anything Wednesday! Off-theme questions in this post will be removed to try and keep the thread a manageable size for both our readers and panellists. Answering Questions: Please only answer a posted question if you are an expert in the field. The full guidelines for posting responses in AskScience can be found here. In short, this is a moderated subreddit, and responses which do not meet our quality guidelines will be removed. Remember, peer reviewed sources are always appreciated, and anecdotes are absolutely not appropriate. In general if your answer begins with 'I think', or 'I've heard', then it's not suitable for /r/AskScience. If you would like to become a member of the AskScience panel, please refer to the information provided here. Past AskAnythingWednesday posts can be found here. Ask away! [link] [comments]  |
| Is there a difference between sleeping late or sleep early if you still get the recommended hours? Posted: 07 Apr 2020 09:51 PM PDT During this time of crisis I have a major question to ask; So I now started sleeping at around 2-3pm after I take my lunch and wake up 12mn-2am the next day. I do still get well over my recommended sleep amount. Is there any health risk or other consequences to this behavior? If it's what I'm now used to for over a month? Link to any information regarding the matter would do great. [link] [comments]  |
| Posted: 08 Apr 2020 05:03 AM PDT If an inactive version of the binding site of ACE2 that the virus uses to access the cell could be synthesised and administered to patients, could it 'flood' the system and compete with normal ACE2 for virus binding, thereby reducing successful interactions and cell entry. What would potential flaws/problems/side-effects be? [link] [comments]  |
| Why we can make plasma with a microwave if it uses non-ionizing frequencies? Posted: 08 Apr 2020 07:45 AM PDT I've seen people putting a grape cut in half in a microwave and making plasma that i know is ionized gas, how could be possible if microwave uses 2.4GHz frquencies that are non-ionizing? [link] [comments]  |
| Posted: 08 Apr 2020 07:02 AM PDT I've heard repeatedly that there are multiple parallel efforts to develop a COVID vaccine as rapidly as possible. What are the details about some of the most promising efforts? Are there any credible projections for how long these projects are likely to take? What makes the process take so long? And finally, are there any easy to fix bottlenecks holding these projects back? Funding, for example? Is there anything we regular folks should be lobbying our political representatives to do to help mitigate any roadblocks that might be slowing down vaccine development efforts? [link] [comments]  |
| Posted: 07 Apr 2020 11:40 PM PDT |
| Posted: 07 Apr 2020 06:23 PM PDT |
| How and when do ants decide that it is time to stop building the anthill? Posted: 07 Apr 2020 09:35 PM PDT How do ants know whether the current size of the anthill is too small? How do they prevent building excessively large anthills? Are there special ants that control the entire process of building the anthill? And how do they spread a signal to stop? [link] [comments]  |
| Posted: 07 Apr 2020 10:39 PM PDT |
| Posted: 07 Apr 2020 08:56 PM PDT This phenomenon has been on the news and on popular posts on Reddit, and most of what I'm hearing is how systemic racism is causing this disparity. Very few people seem to be talking about the specific things that are making these njmbers show this disparity. I don't have a medical background, but I am planning to be a researcher in a different field. I want to know why the numbers are different, so I have a clearer picture of what needs to be fixed. Question 1: Is it just that the total number of deaths of African Americans is higher, or is the fatality rate higher? How do you control for cause-of-death reporting protocols being different at different hospitals? Question 2: In either case, is the why is there a difference? Is the difference in deaths mostly due to increased rates of comorbities among African Americans? Are they because of lower access to healthcare? Question 3: Has the virus spread to more people in African American communities? Is this the same for inner-city, suburban and rural African American communities? Question 4: Does this virus disproportionately affect any lineage due to genetics? How about family history? Question 5: Are there any other ethnicities being disproportionately affected? [link] [comments]  |
| Posted: 08 Apr 2020 12:06 AM PDT Was showering and my hair shampoo was almost finished and this question popped into my mind. [link] [comments]  |
| Posted: 07 Apr 2020 11:56 PM PDT |
| How do various flu vaccines get regularly tested and produced each year to account for mutation? Posted: 07 Apr 2020 10:02 PM PDT It's regularly estimated that the timeline for SARS-CoV-2 vaccines will be 18 months, at least. The bulk of this time seems to be associated with long-term testing in humans as well as ramp-up of vaccine production. Then, it's noted, that if the virus mutates sufficiently fast the vaccine will have limited effect as it fails to target the new variants. That said, we manage the flu today using yearly vaccinations. These vaccinations are also trying to manage the mutating, moving target of influenza, but seem to be regularly decently successful. We hear news of scientists "missing" the right flu variant, but never news about the vaccine being held up in trial. What is different about these two situations? Are there particular biological aspects of influenza that we're able to exploit? Have we developed sufficiently advanced vaccine production that we don't need to perform as much human testing or invest in as much new production capacity? Or is there some other trick that helps to make the flu easier to manage than a novel virus? [link] [comments]  |
| Posted: 07 Apr 2020 08:17 AM PDT I am watching The Brain-David Eagleman. In the first episode, they talk about distortion googles and how it flips your world. What your brain usually sees on the right is flipped and viceversa. If I wear them long enough to get used to it and then take them off, would my brain adapt instantly to how it has been seeing the world during all these years? Or will it take a while which would be frightening?? EDIT: perhaps I should have continued watching instead of pausing to write this post Lol. Apparently it takes about a day to get back to normal. So...frightening! [link] [comments]  |
| What is the risk that Covid-19 mutates into a mosquitoe-borne viral infection? Posted: 08 Apr 2020 05:00 AM PDT So far we've lived the covid-19 crisis from a winter and spring perspective. How about a time where mosquitoes will be ubiquitous? [link] [comments]  |
| Why aren’t monoclonal antibodies used for more drugs/vaccines? Posted: 07 Apr 2020 10:57 PM PDT I learned about monoclonal antibodies in my IB Biology course earlier this year, and they sound like an amazing, maybe even a miracle, process. I believe I learned that receiving monoclonal antibodies is a form of passive artificial immunity. Since they are made with rapidly dividing tumour cells, theoretically it should be possible to produce high yields of the antibodies in a lab right? Why is this process not used more? Given the current environment, why are they not used more in the case of developing vaccines? Perhaps they are used more often than I think and I just haven't heard about it much, but I would love it if someone could explain the above and limitations regarding this process. [link] [comments]  |
| How will social distancing and shelter at home practices effect diseases other than Covid-19? Posted: 07 Apr 2020 10:10 PM PDT I keep imagining that Flu season will be almost non-existent because no one is really out spreading it. But how much less of a Flu season should we expect? What are the ranges of decrease we can expect? Also, a related question; if everyone on Earth were able to quarantine and isolate for 14-21 days, the virus would be pretty much through right? Wouldn't that also eliminate a bunch of other viruses/diseases? Would it be a practical thing to just plan week-ish long, global, shelter-at-home with some regularity just to diminish infectious diseases? Kind of like a Christmas holiday, except everyone stays home/isolated? Also, to prepare us for the next global, month long shut in? [link] [comments]  |
| From seeing the supermoon tonight it made me curious, is there ever a night with no moon? Posted: 08 Apr 2020 12:12 AM PDT To clarify I don't mean a new moon, but it more like on the other side of the planet. [link] [comments]  |
| Why are fires around Chernobyl increasing radiation levels? Posted: 07 Apr 2020 12:30 PM PDT I've seen several articles talking about increased radiation levels near Chernobyl due to grass/forest fires, but none of them say why a fire would cause increased radiation in a previously affected area. My initial guess was that the plant life has "absorbed" latent radiation, but now that it's on fire, it's being spread through ashes. I know this is wrong because radiation is energy, so it isn't just sitting in the plants. Could someone fill in the gaps of my knowledge? Thanks! [link] [comments]  |
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