What happens if we delay the second dose for AstraZeneca vaccine to 12+ weeks after the first one? | AskScience Blog

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Friday, June 25, 2021

What happens if we delay the second dose for AstraZeneca vaccine to 12+ weeks after the first one?

What happens if we delay the second dose for AstraZeneca vaccine to 12+ weeks after the first one?


What happens if we delay the second dose for AstraZeneca vaccine to 12+ weeks after the first one?

Posted: 25 Jun 2021 02:55 AM PDT

Why do waves always move towards the shore?

Posted: 25 Jun 2021 05:30 AM PDT

Do tides levels predict sinkhole formation in seaside areas?

Posted: 24 Jun 2021 07:43 PM PDT

Apologies in advance if the question begs anti-science supposition about current events.

The recent collapse of a condominium happened after 3 days of the highest tides of the month in Miami. What's more, it happened 15 minutes prior the lowest tide. after two days of tides in excess of 3 feet (highest of the month), about an hour before the low tide. Naturally, I'm wondering if there has been any observed co-occurrence of tides and subsidence.

Edit: And naturally I have misconjugated the question. Do tide levels..., Does tide level...

Second edit: facts corrected.

submitted by /u/uiuctodd
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If a reptile, that uses Van Der Waals forces to stick to walls, were to die whilst stuck to a surface, would it stay in place?

Posted: 25 Jun 2021 04:39 AM PDT

How are dolphins or bats able to echolocate in large groups without interfering with other group members clicks?

Posted: 24 Jun 2021 11:11 PM PDT

Put another way, how does one animal know that sound it is receiving is it's own echo vs the echo or primary click of another member of the group?

submitted by /u/cdubyadubya
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Does name familiarity create unintended bias?

Posted: 25 Jun 2021 08:02 AM PDT

I know there has been some research done around unintended name discrimination, especially in hiring practices, but I was wondering if there is any data on more general familiarity bias?

A recent example that made me think of this - I'm in sales and I've been having kind of a stressful morning, feeling a little cranky. You know how it is. I had a customer I'm not familiar with reach out and ask me for free accessory product with their purchase. This is at my discretion since I manage my own P/L - this particular customer had a name very similar to a close friend of mine who I'm looking forward to seeing this weekend and recalling that made me feel a little happier. I immediately approved the request. I'm not 100% sure I would have done that if they had a name I didn't feel connected to.

So is there a measurable amount of favoritism that people give to strangers who have names similar to those they are close with. In contrast, could there be negative bias? If you hate your boss and then meet a friend of a friend with a similar name, are you more likely to have a negative first impression? How could you even measure this?

Thanks, looking forward to the discussion!

submitted by /u/upnflames
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Why doesn't Thermus Aquaticus' DNA degrade at high temperatures?

Posted: 24 Jun 2021 09:46 PM PDT

I know DNA polymerase from Thermus Aquaticus is used for PCR because it can withstand the heat necessary to melt DNA because TA lives at boiling temperatures. But then why doesn't TA's own DNA degrade in vivo? As far as I know, unlike its specialized polymerase, its DNA has the same chemical composition as other organisms.

submitted by /u/steakknife
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Are there any long-term (>20 years) cycles in habitats and species? (Ecology)

Posted: 25 Jun 2021 06:01 AM PDT

Are there long-term (>20 years) cycles in habitats and species? From what I can find, examples of medium term cycles are sand dunes or estuarian ecosystems, or repeating patterns in disease outbreaks for species.

I'm very interested in the possibility of longer termrepeating cycles that may exist in for instance forests instead of just succession towards a stable state. I only know this to be the case for fire-mediated ecosystems, but even for those cycles seem to be shorter (ca. 15 yrs in Fynbos for instance). If these ecosystems with long term cycles have existed, do these conditions still exist in some places?

I tried searching for these on google scholar, but all studies I could find were either shorter term, showing directional trends or theoretical modelling studies. Any references or answers will be much appreciated.

Thanks in advance!

submitted by /u/rakketakke
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Do we get more energy from trans fat as compared to monosaturated fat?

Posted: 25 Jun 2021 04:42 AM PDT

I saw an article on how an animal study showed that diet with trans fat resulted in greater weight gain despite containing the same calories as a diet with monosaturated fat (https://www.sciencedaily.com/releases/2006/06/060619133024.htm).

Does this imply that trans fats are actually higher in calories hence actual total calories in diet is different or am I misunderstanding the weight gain of the monkeys as being from energy surplus -> conversion into fat deposits -> weight gain?

submitted by /u/enzxc
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Are mostly megabats the important, dangerous virus transmitters (of the corona virus, the ebola virus...)?

Posted: 25 Jun 2021 06:31 AM PDT

In the German language, we distinguish sharply between Fledermäuse (bats) and Flughunde (bats, Megabats, flying foxes).

In these times you read everywhere, that bats are very important transmitters of viruses. We have quite a few bats (only "Fledermäuse") in these parts of Germany, but I never heard they are important transmitters.

Questions: Are mostly megabats the important, dangerous virus transmitters (of corona, ebola ...)?

Thank you!

submitted by /u/koenighotep
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What happened to curing paralysis through Olfactory Cell Transplantation?

Posted: 25 Jun 2021 12:46 AM PDT

I found an article about Darek Fidyka, who was the first person ever to have his paralysis "cured" back in 2014 through Olfactory Cell Transplantation.

This was in 2014, and updates about Darek show it's worked well so far. Why hasn't there been any more progress or trials for this? If it was successfully completed in 2014, shouldn't 7 years have led to immense progress in the field?

submitted by /u/Jaloss
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J&J Janssen vaccine has the lowest rate of efficacy, and is also the only one with a single dose. Are these statements related? Wouldn't it benefit from a booster shot too?

Posted: 25 Jun 2021 07:57 AM PDT

Is there any evidence of anthropogenic climate change prior to the industrial revolution?

Posted: 25 Jun 2021 06:55 AM PDT

Big fat disclaimer: I'm not a fossil fuel apologist nor am I looking for arguments to excuse the current rapid climate change for which we humans are almost certainly responsible.

Considering the fact that we can look at ice cores, etc., to makes inferences about past climate trends, I'm curious to know whether there is evidence that earlier human developments, such as agriculture and widespread burning of organic matter, had a measurable effect on global climate.

(Sorry if I chose the wrong flair. There's definitely some overlap in this question between earth sciences, archeology, and anthropology.)

submitted by /u/straycanoe
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What is the correct term for when the effects of an isolated variable cannot be accurately identified in the context of a large robust study? Esp. in relation to nutrition science.

Posted: 25 Jun 2021 06:39 AM PDT

Sorry for messy title but I'm not exactly sure how to ask this.

Example:

------------

Compound madeup123 has been shown to raise blood pressure. This has been shown in short-term, clinical experiments, by administering the compound to test subjects, and taking measurements.

It turns out that the goofball fruit, which we have all been enjoying for years, has been shown to have relatively high levels of madeup123.

Dr. Jon Smith, in his latest diet book, puts the goofball fruit on his list of foods to avoid, citing the experiments with compound madeup123, connecting it to increased risk of heart attack, stroke, and damaged arteries.

-----------

I have a friend who seems to switch to a different diet every few years. Inevitably he has some book to show me, which "proves" that this diet is the best one. Sometimes its written by a medical professional, sometimes not. Littered throughout the book are examples like what I have written above.

But here is the crux of my question: The direct mechanism of action, related not to the well-understood pharmacology, but to later outcomes like increased risk of death, is never explained.

I understand this is different than trying to look at a large database of outcomes, and trying to draw some general conclusions. E.g. - a study of 300k coffee drinkers shows that drinking a cup a day extends your life by a few years. Ok, I'm skeptical of some of these, but I get it. This is different than the example I've given.

But these fad diet books are rife with the kind of thing I'm talking about and sometimes it drives me bonkers. Either something wonky is going on here or I'm just not understanding something. If its the latter than thats fine with me, please educate me. What is the technical term for this sort of thing - statistical significance, or noise....or something else?

What am I missing?

submitted by /u/BlueGumShoe
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Does Sleep/Dream Activity follow a Cycle?

Posted: 25 Jun 2021 04:02 AM PDT

EDIT: Title is misleading. I don't mean a cycle during the night, I mean a cycle lasting weeks (inter-night instead of intra-night, let's say).

I feel like my sleep is lighter during nights around a full moon, I move a lot during those nights and I often dream a lot more. It may be a placebo effect obviously, but many times I actually woke up after a light sleep night and discovered that it was a day with a full or near-full moon.

Please believe me when I say I don't believe in Astrology or similar magical rubbish. Are there any scientifical studies on this matter or I'm just delusional? Thank you.

submitted by /u/Voxel_B
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JJ and AZ vaccines very rarely cause massive blood clotting. Is there any science on the possibility of sub clinical blood clotting occurring more often?

Posted: 25 Jun 2021 12:07 AM PDT

In this Video, there is an explosion and the water turns light blue for a split second. Why does this happen?

Posted: 24 Jun 2021 12:50 PM PDT

Do mRNA/viral vector vaccine adverse events have a common cause ?

Posted: 24 Jun 2021 01:56 PM PDT

@mods: rephrased according to guidelines

Question on (sub clinical) myo/pericarditis / CVST post vaccination

All of the current COVID-19 vaccines used in the US and Europe, seem to have (rare) inflammation issues associated with them. The JJ and AZ (viral vector) vaccines rarely produce a rare blood clotting disorder (CVST/SVT) and the Pfizer and Moderna (mRNA) vaccines seem to be associated with a rare inflammation of the (lining of the) heart (myo/pericarditis).

My questions: 1. Are all of these inflammation issues caused by the common mechanism these vaccines have, of instructing our cells to express the spike protein, which cells are then attacked by our immune system through an inflammatory response? 2. Has it been researched as part of the clinical trials, or afterwards, wether the mRNA vaccines also produce sub clinical pericarditis and/or whether viral vector vaccines lead to sub clinical blood clotting in more recipients than is readily observable (given the fact that adverse events during trials are mostly self reported and even mini strokes due to clots in the smallest blood vessels of the brain often go unnoticed by the patient)? 3. Does the inflammatory response dissipate completely after all the vectors / mRNA proteins have been destroyed by the immune system? How long would it take to identify a (latent) auto immune response vis-a-vis the type of cells that previously expressed spike proteins ?

submitted by /u/HammerTim81
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When Does A Water Rocket Reach Maximum Velocity?

Posted: 24 Jun 2021 12:57 PM PDT

Is it at the moment when all the water inside the rocket has been pushed out?

submitted by /u/OtakuKing613
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How was the first code ever made?

Posted: 24 Jun 2021 07:45 AM PDT

How was the first ever code made? A computer needs drivers for a keyboard and that requires code but to code you need a computer

submitted by /u/MadDog2504-TTV
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How does running liquid through the compressor in a refridgerator act as a heat exchanger? Does compressing the liquid cool it somehow? What incites the transfer of thermal from an area of medium-energy to another area of medium energy?

Posted: 24 Jun 2021 05:03 PM PDT

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