- AskScience AMA Series: I'm Alexis Kaushansky, a Principal Investigator at the Center for Infectious Disease Research in Seattle, WA. I research malaria and the interactions between host and pathogens. I’m excited to talk to you about it. AMA!
- In a microwave, why doesn't the rotating glass/plastic table get hot or melt?
- Throughout history were doctors able to diagnose allergies or were they misdiagnosed as something else?
- What the hell is entropy? How can we quantify something as abstract as "disorder"?
- Do short trees bud/blossom faster than tall trees?
- How would a person with slight to moderately low levels of grey matter function? White matter as well?
- Would the clone of an animal with inherited heterochromia also have it? Would it be on the same side?
- Is there a maximum density?
- Can diabetes type 2 be reversed or "cured"?
- Read a really strange article that says we need bacteria (p. Syringae) to make rain and it was full of microbiologist quotes. Is this a commonly accepted theory?
- What did people think prior to cell theory?
- What is Doppler/Laser Cooling (and other questions related to the practice)?
- Are most human genes under Hardy-Weinberg Equilibruim?
- Why does aging cause faces to lose fat under the skin?
- When I add cream or milk to my coffee to mellow it out, is the coffee actually changing chemically in some way? Or is the dairy just masking the coffee's acidic character and tricking me?
- How do firearm scopes accurately predict where a bullet will land when it is slightly above from where the bullet is fired?
- Why does an electric motor interfere with TV reception?
- Recording tinnitus - can you measure it?
- Liquid nitrogen excessive boiling before critical temperature?
- Does the excessive comsuption of violent media has any effect on us?
- Do the lungs, rather the bronchii and alveoli inside them fill from top to bottom, or vice versa?
- Why do some metals corrode faster than others?
- What type of computer / communications hardware / software was used on the Lunar Landing Missions (Apollo)?
| Posted: 25 Apr 2016 04:53 AM PDT Hello Reddit! My name is Alexis Kaushansky and I serve as a principal investigator at the Center for Infectious Disease Research. My research studies the interactions between humans and pathogens, with a particular focus on malaria. The malaria parasite and other infectious diseases that burden the world cannot survive independently. To cause sickness and travel through the population, they must appropriate resources from the people they infect. Our work aims to identify what pathogens need from their host and use this knowledge to prevent and ultimately eliminate malaria. When malaria parasites are transmitted from mosquito to human, they are first deposited into the skin, then quickly travel to the liver. In the liver, each parasite replicates tens of thousands of times within the confines of a single hepatocyte, a cell in the liver. During this stage of infection, the parasite causes no clinical symptoms, yet elimination of the parasite in the liver prevents disease and transmission and can even elicit sterile immunity from subsequent infection. Our work focuses on the basic question of how the malaria parasite is able to modify its human liver environment in order to counteract host defenses and ensure for its own survival. At CIDResearch, we breed thousands of research grade mosquitoes each week in order to power our bench research projects. Our work critically depends on malaria parasite infection in mosquitoes and production of sporozoites for lab experiments. We maintain state-of-the-art insectaries that breed and house Anopheles mosquitoes. Here are a few of our recent publications: Suppression of host p53 is critical for Plasmodium liver-stage infection. http://www.ncbi.nlm.nih.gov/pubmed/23478020 Malaria parasites target the hepatocyte receptor EphA2 for successful host infection. http://www.ncbi.nlm.nih.gov/pubmed/26612952 To mark April 25 World Malaria Day, I'm taking questions on the research underway to better understand and combat this ancient disease. I will be back at 12 pm ET to answer your questions, looking forward to it! [link] [comments]  |
| In a microwave, why doesn't the rotating glass/plastic table get hot or melt? Posted: 24 Apr 2016 10:04 AM PDT |
| Posted: 24 Apr 2016 09:50 PM PDT |
| What the hell is entropy? How can we quantify something as abstract as "disorder"? Posted: 24 Apr 2016 09:07 PM PDT I'm aware entropy can be thought of as "unusable energy" but what does that even mean? How does this occur? It sounds just like an exception to the conservation of energy. How exactly is this tied into chaos and disorder? [link] [comments]  |
| Do short trees bud/blossom faster than tall trees? Posted: 24 Apr 2016 06:40 PM PDT I was out for a walk today, and I made an observation that most of the tall trees that I saw were still bare, whereas most of the short trees had blossomed. Is this because it takes longer for tall trees to draw nutrients up the trunk in the spring than short trees? Or is it because the "tall trees" are really just a different species and would take longer to blossom even if they were shorter? [link] [comments]  |
| Posted: 24 Apr 2016 06:05 PM PDT Not looking for a full blown disorder, but more so a slight nuance to a moderate anomaly, similar to the cortical variability in any given population. [link] [comments]  |
| Posted: 24 Apr 2016 06:03 PM PDT |
| Posted: 24 Apr 2016 12:49 PM PDT If density is just how close the atoms are to each other, surely there's a breaking point for the atoms, right? [link] [comments]  |
| Can diabetes type 2 be reversed or "cured"? Posted: 24 Apr 2016 06:49 PM PDT |
| Posted: 24 Apr 2016 08:48 PM PDT Heres the place I read it. Still can't believe I've never heard this before. http://www.theverge.com/2016/4/22/11486644/ice-crystal-bacteria-process-study [link] [comments]  |
| What did people think prior to cell theory? Posted: 24 Apr 2016 08:23 PM PDT Did they believe that humans were just singular, large organisms or was there a precursor to the concept of cells? [link] [comments]  |
| What is Doppler/Laser Cooling (and other questions related to the practice)? Posted: 25 Apr 2016 05:21 AM PDT Hi there, science people! I have a few questions about Doppler Cooling! Lets get started :)
Sources would be great. Thank you so much! [link] [comments]  |
| Are most human genes under Hardy-Weinberg Equilibruim? Posted: 24 Apr 2016 07:01 PM PDT Aside from the genes (and their surrounding loci) that are under selection, are most human genes in HWE? [link] [comments]  |
| Why does aging cause faces to lose fat under the skin? Posted: 24 Apr 2016 08:38 PM PDT |
| Posted: 24 Apr 2016 03:56 PM PDT |
| Posted: 24 Apr 2016 08:21 PM PDT If the barrel is below the scope, than how does the scope accurately predict where the bullet will land? Wouldn't the bullet land slightly below where the scope predicts it will, since the barrel is slightly below the scope? [link] [comments]  |
| Why does an electric motor interfere with TV reception? Posted: 24 Apr 2016 08:11 PM PDT My digital antenna signal loses some reception when a certain powerful electric motor is used nearby. I have a moderate understanding of electronics, but I was really surprised when this happened. [link] [comments]  |
| Recording tinnitus - can you measure it? Posted: 24 Apr 2016 04:05 PM PDT I was once at an audio engineering society meeting where headphone experts were talking about how tinnitus can be an oscillation. I was told that it could actually be recorded if the ear was in the a room like an anechoic chamber. Could anyone fill me in if this were possible? Thanks Reddit. [link] [comments]  |
| Liquid nitrogen excessive boiling before critical temperature? Posted: 24 Apr 2016 10:03 AM PDT I've used liquid nitrogen for the last few years as a low temperature reference point for the calibration of PRTs (Platinum Resistance Thermometers). The process of which involves a filling a 2 liter dewar flask and submerging a copper block inside of it. The process of getting the copper down to the boiling point of the liquid nitrogen takes about 10-12 minutes, for those curious, but what I want to know happens RIGHT before it reaches thermal stability. About 30 seconds before thermal stability the nitrogen starts to boil more vigorously. It "erupts" from the holes at the top of my test set up and shoots a huge cloud of water vapor (from the air) and droplets of liquid nitrogen everywhere. So my question is this: Why do objects submerged in liquid nitrogen cause it to boil more rapidly when they reach the boiling point (-196°C)? [link] [comments]  |
| Does the excessive comsuption of violent media has any effect on us? Posted: 24 Apr 2016 02:51 PM PDT |
| Do the lungs, rather the bronchii and alveoli inside them fill from top to bottom, or vice versa? Posted: 24 Apr 2016 04:34 PM PDT |
| Why do some metals corrode faster than others? Posted: 24 Apr 2016 04:31 PM PDT If the environment is the same,why do some metals form rust faster than others. I.e. Copper in sulfuric acid vs steel in sulfuric acid [link] [comments]  |
| Posted: 24 Apr 2016 03:39 PM PDT Couldn't find much info on:
Considering commercial air travel relies Heavily on "fly-by-wire" / computerized Systems, GPS, VHF radio, RADAR, etc, How did NASA pull off getting a Lander, As well as a Lunar Escape / Earth Re-Entry craft to the moon and back without the items less-intense aviation such as Commercial Air Traffic uses today. It's my understanding that a smart-phone today likely has more computing power than NASA had in its entire Mission Control in 1969. How was this feat accomplished lacking the hardware and software we have today? (Which almost begs the question "why haven't we ever returned to the Moon?" Given it should be exponentially easier in 2016 than it was in the late 1960's / early 1970's) [link] [comments]  |
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