Why are men in western countries half as fertile today as they were in the 1970's? What is the biggest contributor to this recent Male Fertility Crisis? | AskScience Blog

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Wednesday, September 29, 2021

Why are men in western countries half as fertile today as they were in the 1970's? What is the biggest contributor to this recent Male Fertility Crisis?

Why are men in western countries half as fertile today as they were in the 1970's? What is the biggest contributor to this recent Male Fertility Crisis?


Why are men in western countries half as fertile today as they were in the 1970's? What is the biggest contributor to this recent Male Fertility Crisis?

Posted: 28 Sep 2021 07:30 PM PDT

I just saw this short Vice documentary called Spermageddon that talked about the Male Fertility Crisis.

The video referenced a meta analysis quoted below in an article in The Guardian.

The study, published in the journal Human Reproduction Update by an international team of researchers, drew on 185 studies conducted between 1973 and 2011, involving almost 43,000 men. The team split the data based on whether the men were from western countries – including Australia and New Zealand as well as countries in North America and Europe – or from elsewhere.
After accounting for factors including age and how long men had gone without ejaculation, the team found that sperm concentration fell from 99 million per ml in 1973 to 47.1 million per ml in 2011 – a decline of 52.4% – among western men unaware of their fertility.
For the same group, total sperm count – the number of sperm in a semen sample – fell by just under 60%.
Richard Sharpe, an expert in male reproductive health and professor at the University of Edinburgh, welcomed the study, saying the research has tackled many of the problems of previous analyses, adding that it "is about as close as we are going to get" to being sure of the decline.
But he stressed it still unclear what is behind the drop, meaning that it is difficult to address. "That is primarily because we have seriously under-invested in male reproductive research," he said.

The Vice video showed an interview with Epidemiologist Dr. Shanna Swan of the Icahn School of Medicine, who said that sperm concentration is falling on average about 1% per year. She said that when sperm concentration drops below 40 million per ml, you start to have trouble conceiving.

The Vice video mentioned some suspected reasons for male fertility problems like

  • increased exposure to endocrine disruptors like plastics
  • poor quality/quantity of sleep
  • poor diet

So, experts are saying it's unclear what's behind the Spermageddon, but I don't buy it. Some questions I have:

  1. What has changed since the 1970's that is contributing to male infertility?
  2. What is the largest contributor to male infertility today?
  3. What were men 40 years ago doing that was making them more fertile than men today?
submitted by /u/JayT1D
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AskScience AMA Series: I am Geoff Barnes, M.D., a cardiologist and vascular medicine specialist at the University of Michigan Health System in the US. Today is World Heart Day and I am excited to be here to answer your questions about all things heart health and blood clots. Ask me anything!

Posted: 29 Sep 2021 04:00 AM PDT

I'm Geoff Barnes, M.D., and I work as a cardiologist and vascular medicine specialist at the University of Michigan Health System in the United States. You can follow me on Twitter at @GBarnesMD. My professional areas of interest include anticoagulation, venous thromboembolism, quality improvement and shared decision-making. I'm currently leading multiple NIH- and AHRQ-sponsored studies to improve the safety for patients on chronic anticoagulants. In honor of World Heart Day, I'm here to answer anything you want to know about heart health and blood clots. For instance, did you know that people with atrial fibrillation (AFib) are at greater risk for stroke and are estimated to account for 15% of the 15 million strokes that occur worldwide every year? I'll get started around 2pm ET (18 UT) - AMA!

Username: /u/WorldThrombosisDay

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Ask Anything Wednesday - Biology, Chemistry, Neuroscience, Medicine, Psychology

Posted: 29 Sep 2021 07:00 AM PDT

Welcome to our weekly feature, Ask Anything Wednesday - this week we are focusing on Biology, Chemistry, Neuroscience, Medicine, Psychology

Do you have a question within these topics you weren't sure was worth submitting? Is something a bit too speculative for a typical /r/AskScience post? No question is too big or small for AAW. In this thread you can ask any science-related question! Things like: "What would happen if...", "How will the future...", "If all the rules for 'X' were different...", "Why does my...".

Asking Questions:

Please post your question as a top-level response to this, and our team of panellists will be here to answer and discuss your questions. The other topic areas will appear in future Ask Anything Wednesdays, so if you have other questions not covered by this weeks theme please either hold on to it until those topics come around, or go and post over in our sister subreddit /r/AskScienceDiscussion , where every day is Ask Anything Wednesday! Off-theme questions in this post will be removed to try and keep the thread a manageable size for both our readers and panellists.

Answering Questions:

Please only answer a posted question if you are an expert in the field. The full guidelines for posting responses in AskScience can be found here. In short, this is a moderated subreddit, and responses which do not meet our quality guidelines will be removed. Remember, peer reviewed sources are always appreciated, and anecdotes are absolutely not appropriate. In general if your answer begins with 'I think', or 'I've heard', then it's not suitable for /r/AskScience.

If you would like to become a member of the AskScience panel, please refer to the information provided here.

Past AskAnythingWednesday posts can be found here. Ask away!

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Can there be several RNA polymerases transcribing RNA from DNA during transcription?

Posted: 29 Sep 2021 02:36 AM PDT

What makes a sponge an animal?

Posted: 28 Sep 2021 04:01 PM PDT

My understanding of Poriferans is that they consist of cells that are all working independently, with no true tissues or higher level of organisation. Why then, are they considered multicellular animals rather than an aggregation of unicellular eukaryotes? What differentiates the sponges?

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How did scientists first figure out what the internal structure of a cell looks like? Was a microscope able to show individual parts?

Posted: 28 Sep 2021 10:08 AM PDT

Why is the shingles vaccine only offered to people over 50?

Posted: 28 Sep 2021 08:42 PM PDT

Does removing the right medial temporal cortex and hippocampus make you lose all your visual memory?

Posted: 29 Sep 2021 04:00 AM PDT

I heard that visual memory was stored in right side of the brain and was wondering if the title above would be true and if so, would that make us unable to have mental images?

submitted by /u/Frequent-Trick4149
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Is there an impact on injections/vaccines from exercise shortly afterwards?

Posted: 28 Sep 2021 09:46 PM PDT

Is there any impact on effectiveness of vaccines or incidence of minor side effects(ie arm pain), from doing exercise shortly after receiving an IM injection?

submitted by /u/ForumUser013
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Pangea: how did the oceans form?

Posted: 29 Sep 2021 01:30 AM PDT

Originally, Pangea was a big landmass. As the plates moved away from each other, a gap was left between, which made an ocean. My question is this: what would an ocean forming look like? Would it be a very slow river starting to appear, that then widens? A gap that forms below sea level that then fills up through water drainage in the sides? Or a gap that goes below sea level until a point when the gap suddenly touches an ocean and it all rushes in?

Tldr: seeping, river or big sploosh?

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What gives different flavours of quarks their respective properties?

Posted: 28 Sep 2021 07:14 PM PDT

Eg what actually makes an up and down quark have different charges? Does it have something to do with magnetic moments & angular momentum?

submitted by /u/MadMan1244567
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Why does light in a aurora form the patterns it does, that look like waving strands and curtains, and not just simply a diffuse glow?

Posted: 28 Sep 2021 09:15 AM PDT

Or maybe with some turbulent motion. But the kinds of formations it does appear as: that looks like something that has a story behind it.

submitted by /u/Jillian_Wallace-Bach
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Could/do peptide bonds form between amino acid R groups?

Posted: 28 Sep 2021 07:22 PM PDT

Obviously it's not supposed to happen, but does it, if only to be immediately undone? Take aspartate for example; what's stopping the R group carboxylic acid from reacting with an amine group in place of the "main" carboxylic acid? If this DOES happen, what is the result?

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What form of energy do electrons lose/gain when moving across a potential difference?

Posted: 28 Sep 2021 05:05 PM PDT

Consider a basic circuit where a 9V battery is connected directly to a 9kΩ resistor. The current will be 1mA everywhere, meaning there is a constant rate of electron flow through any given point in the circuit.

The potential difference across the battery and resistor are both 9V. Voltage is measured in joules per coulomb (volts), suggesting that the average electron has more energy before flowing through the resistor than after. The classic explanation I've heard is that electrons flowing quickly through a narrow resistor tend to collide with the static nuclei, releasing heat and reducing the electrons' kinetic energy. However, since the electron flow rate is the same at all points in the circuit, the electrons should have the same amount of kinetic energy on both battery terminals (and thus on both ends of the resistor).

Considering this, when moving across a potential difference like a battery or a resistor, what form of energy do the flowing electrons actually gain/lose?

submitted by /u/JWson
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If you have a circuit with a component that uses 8 Volts, what would happen to the remaining voltage if you used a voltage supply of more than 8 volts?

Posted: 28 Sep 2021 08:54 AM PDT

Might be a really dumb question but if you go beyond the 8 volts when the system only requires only 8 volts, what would happen to remaining voltage in in the system?

For example if I used a 10 voltage battery, would the battery only release 8 volts or would you need somehow adjust current/resistance to be able to run the system without overheating the component?

Edit: Thank you for all the replies as they all helped me grasp the concept a lot more easier :)

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What (if anything) besides the new Delta variant has made Covid so much more deadly among the unvaccinated?

Posted: 28 Sep 2021 04:25 PM PDT

I was reading a /r/bestof post inspired by this comment.

What got me was the comment "... we used to work hard and some people got better. Now we work hard and almost nobody gets better..."

My wife works in healthcare and tells me the same thing - compared to "early Covid" pre-vaccine times, it seems more and more like once unvaccinated people need BiPAP (i.e. HiFlow O2 is not enough) things now seem to inevitably progress to a one-way trip down BiPap / Intubation / ECMO / death. The percentage who get better from these levels seems much lower than it did.

Is this just my wife and my imaginations? Or has something about the nature of the disease evolved to make it more deadly once you get beyond a certain point?

submitted by /u/foodfighter
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Metaphorically speaking: Is a Lagrange point a hill, a plain, or a valley?

Posted: 28 Sep 2021 05:56 PM PDT

By Metaphorically speaking I mean in terms of getting there and staying there.

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What happens to fish (and other aquatic animals) during a severe flash flood?

Posted: 28 Sep 2021 12:25 PM PDT

The back-to-back flooding from Henri and Ida (both in August) carved out a few feet from the banks of the section of creek in the backyard of my home (in the US northeast) with a corresponding drop in water level. I've seen very few fish since in the creek after the flooding. What happens to fish (and frogs, crayfish, and other creek-dwelling animals) during and after a big flash flood?

submitted by /u/Wyatt_Urp
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How do we calculate the greenhouse influence of various gases in the atmosphere?

Posted: 28 Sep 2021 05:11 PM PDT

Context about what I need the answer for: I'm doing a speculative evolution project using a planet with an atmosphere both thicker and richer in CO2, and I'd like to get more detailed information about the effect that has on temperature, especially with some of the other factors I have going on with the planet. I would also like to be able to generate such information for myself in future projects, so I'm looking for an equation; or at least a pattern of derivation that can lead me to a very rough semblance of an equation. I know the partial pressures of the composition of my atmosphere, the solar flux, and the planets average albedo. How do I get to an average planet temperature with that?

- - - me trying to guess, feel free to ignore - - -

So, if I take the energy coming from the sun (F=solar flux), and multiply it by the amount left over after some is reflected away as light (A=1-planet bond albedo), then that's the amount of energy that eventually has to leave the planet in the form of heat radiation (R=total escape radiation=FA). So if I find the fraction of energy not trapped by the atmosphere (E=radiation escape rate), then I should be able to multiply that by the actual surface energy (S=surface energy) to get R. Thus I have the equation ES=R, but I want to solve for S, so it becomes S=R/E. and R=FA, so S=FA/E

Now, E is the tricky part. The way I think about it, this fraction is equivalent to the odds of a particular unit of heat escaping without being reflected back to earth by any given unit of the atmosphere. When you double the atmosphere density, you're adding twice as many chances to be reflected. So if the odds of escape at 1 unit of atmosphere are X, then the odds at 2 units are X^2, and so on. Think like if you were rolling a die for each unit of atmosphere, trying to get at least one 6. More atmosphere, more dice. Since X is a fraction less than 1, that means diminishing returns per unit of atmosphere. However, each type of gas has different inherent odds of redirecting energy.

This is where I'm running into tons of trouble. The greenhouse power of a gas, or it's 'radiative efficiency' (G= radiative efficiency) is defined as "the change in 'energy flow' (I guess that means the amount of energy reflected back to earth? I'll call it T.) per part (p=total parts of reference gas) per billion (B=total parts in atmosphere). G=TP/B. My main problem with this, which is a VERY big problem, is that you can solve that equation with the same B as jupiter, and as long as P rises proportionately, T will never change.

In any case, if I try to model the situation using T instead of E, then I get energy coming in to the planet, a smaller amount coming out, and this T value that just sits there. But that T has to go somewhere, and theres more F coming in, so FA+T gets reflected back to the atmosphere, and T gets reflected back to surface again, releasing FA to space and finding equilibrium. Thus S=FA+T. I wouldve thought that energy release was proportional to the amount of energy present though.

submitted by /u/Taloir
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Why does Covid-19 cause decreased white blood cell counts?

Posted: 28 Sep 2021 09:03 AM PDT

During acute covid-19 infection patients are seen to have decreased white blood cell counts. Is this due to SARS-cov-2 actually infecting white blood cells or just inflammation destroying WBCs?

Can COVID infect T cells? Specifically CD4 cells?

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