Why do we hear about breakthroughs in cancer treatment only to never see them again? | AskScience Blog

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Tuesday, June 9, 2020

Why do we hear about breakthroughs in cancer treatment only to never see them again?

Why do we hear about breakthroughs in cancer treatment only to never see them again?


Why do we hear about breakthroughs in cancer treatment only to never see them again?

Posted: 08 Jun 2020 04:35 PM PDT

I often see articles about breakthroughs in eradicating cancer, only to never hear about them again after the initial excitement. I have a few questions:

  1. Is it exaggeration or misunderstanding on the part of the scientists about the drugs' effectiveness, or something else? It makes me skeptical about new developments and the validity of the media's excitement. It can seem as though the media is using people's hopes for a cure to get revenue.

  2. While I know there have been great strides in the past few decades, how can we discern what is legitimate and what is superficial when we see these stories?

  3. What are the major hurdles to actually "curing" cancer universally?

Here are a few examples of "breakthrough" articles and research going back to 2009, if you're interested:

2020: https://www.google.com/amp/s/www.bbc.com/news/amp/health-51182451

2019: https://www.sciencedaily.com/releases/2019/06/190604084838.htm

2017: https://www.google.com/amp/s/time.com/4895010/cancers-newest-miracle-cure/%3famp=true

2014: https://www.sciencedaily.com/releases/2014/03/140325102705.htm

2013: https://www.cancerresearch.org/blog/december-2013/cancer-immunotherapy-named-2013-breakthrough-of-the-year

2009: http://www.cnn.com/2009/HEALTH/12/17/cancer.research.breakthrough.genetic/index.html

TL;DR Why do we see stories about breakthroughs in cancer research? How can we know what to be legitimately excited about? Why haven't we found a universal treatment or cure yet?

submitted by /u/throwaway63257
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If breaking the sound barrier causes a sonic boom, what would breaking the light speed barrier do?

Posted: 08 Jun 2020 08:50 AM PDT

How does a computer know when to shutdown itself due to overheat?

Posted: 09 Jun 2020 08:25 AM PDT

Like for instance, when the CPU gets to hot, what actually happen? I assume the motherboard reads the temperatures sensors and send a trigger warning to the PSU to cut the power if it's above a threshold, something like that?

Also when it comes to the GPU, can an overheat cause the PC to shutdown or it's only translated with even bigger artefacts all over the screen?

Thanks in advance for the help.

submitted by /u/qS3ra
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Can you kill a virus?

Posted: 09 Jun 2020 09:03 AM PDT

Am not sure if my question qualifies to be here but I really hope someone gets me an answer, be it a relative one... If viruses have no cell, and are basically classified as non-living, can they die? WHO says small pox virus has been eliminated but I don't understand how, given that viruses have a way to stay in a host body inactive for many years... So how do you eliminate something that can "live without being alive"? Thank you

submitted by /u/LordZepha
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Once there's a COVID vaccine, what percentage of the population must be vaccinated to reach herd immunity? How long would this take?

Posted: 08 Jun 2020 08:30 PM PDT

What causes the symptoms of pox diseases?

Posted: 09 Jun 2020 03:19 AM PDT

Why is it that diseases like smallpox and chickenpox cause blisters, postules and papules over the body? Is it an immune response? An evolutionary response so the virus spreads more easily?

I suppose this question extends to other diseases which cause papules, like the plague.

submitted by /u/tickera
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Why doesn't the voltage in a wall socket drop, when I plug a device in?

Posted: 09 Jun 2020 09:03 AM PDT

When I connect a battery to a load, bascially the voltage of that battery goes slowly to zero, because the electrical charge is evening out and also the resistance of the load lowers the voltage from the previous state of no-load.
I assume this would also happen in a wall socket, since I would change from no-load to load, so it would lower the resistance of the electric circuit.
If that is the case: Why does the socket voltage remain stable?

Since I am an communications engineer, I have basic kowledge of electronics, power electronics and power enigneering, so you can be very technical in your answer, but since I haven't used this knowledge since years, I can't answer it myself.

submitted by /u/suuuupercroc994
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How did Newtonian gravity and general relativity's predictions of the bending of light due to gravity differ?

Posted: 09 Jun 2020 07:01 AM PDT

Like general relativity, Newtonian gravity predicts that the presence of the sun will bend star light (according to this Vox video), so that when observing stars around the sun during an eclipse, you will observe some displacement. General relativity predicts a different amount of displacement, hence the famous photo proving Einstein's theory. Why did the two theories predict different amounts of displacement?

submitted by /u/harumphfrog
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Are a symptomatic and pre symptomatic considered different things?

Posted: 09 Jun 2020 08:54 AM PDT

I'm reading a statement that says that at least according to WHO asymptomatic spread of Covid is rare but possible. But I'm not sure if someone who later developed symptoms is considered an a symptomatic case or not.

submitted by /u/maiqthetrue
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Atomspheric lapse rate applied to solids?

Posted: 09 Jun 2020 04:43 AM PDT

The lapse rate which is proportional to g/cp (gravity/ heat capacity) means that the higher you go up in the atmosphere, the cooler it gets. Think white snow capped mountains.

Does this lapse rate formula also apply to solids and explains why it gets hot down the bottom of mines?

Looking at the wikipedia article and derivation there doesn't seem to be anything particular to gases.

Wikipedia Lapse Rate

Applying the lapse rate formula -9.8/Cp to a deep gold mine gives a similar result.

-9.8/800*4000m= 49oC temperature rise

800 is rough Cp for rock 4000m Mponeng Gold mine depth 66oC is temperature at bottom of mine

Gold mine

And average annual temperature is 18.2oC Gauteng province

49+18=67oC

The above is fairly close match so the theory doesn't sound unreasonable to me.

submitted by /u/Tarsal26
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Do monkeys or other apes get chapped lips?

Posted: 08 Jun 2020 09:00 PM PDT

Why are moles (I think Nevi is the correct term) so dangerous?

Posted: 09 Jun 2020 06:52 AM PDT

Since a kid that my parents and doctors tell me to be cautious around the sun and protect my skin, especially any mole. And I know a lot of people that had moles removed without them being cancerous. What differenciates them from normal skin and why are they so dangerous? Are red moles dangerous as well?

submitted by /u/MrDrunkCat
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In terms of evolution which came first ribosomes or proteins ?

Posted: 09 Jun 2020 05:20 AM PDT

Do nerve agents always work by blocking acetylcholinesterase?

Posted: 09 Jun 2020 05:03 AM PDT

After some research I've found that most nerve agents seem to work this way but is this the only way they could work?

submitted by /u/acornstudent777
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Why does your skin itch when you get into a really hot bath?

Posted: 08 Jun 2020 09:16 PM PDT

Google only shows me reasons for why you itch after a hot shower, but my skin itches like crazy the first few seconds after getting into a super hot bath, and I still haven't found anything on why it does.

submitted by /u/astasodope
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If fossil fuels once were a part of the carbon cycle, why is it bad when we emit the carbon back into the air?

Posted: 08 Jun 2020 10:44 PM PDT

Fossil fuels are, well, fossils. And therefore, it was something living that died and didn't decompose. But was the carbon a part of the animal or is it oils from inside the Earth? Why is it bad for the planet to emit carbon dioxide when that level once was a totally normal part of the ecosystems?

submitted by /u/heliumlantan
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Does the influenza virus affect cell size?

Posted: 08 Jun 2020 03:56 PM PDT

For instance, does the cell swell or shrink after infection? I can't find anything online

submitted by /u/JMoneyG0208
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Why doesn’t California get tsunamis?

Posted: 08 Jun 2020 09:01 AM PDT

Is it possible to have a region of a gravitational field with non zero curl?

Posted: 08 Jun 2020 02:53 PM PDT

Yes curl as in mathematical curl in the vector field. In what situation(s) would this happen, if it is possible?

submitted by /u/Deleizera
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In turbulent fluid dynamics, why does the isotropic part of Reynolds stress tensor not transfer momentum?

Posted: 08 Jun 2020 02:12 PM PDT

I have come across the statement in an online lecture, "Only the anisotropic term is effective in turbulent transport of momentum." I understand that the isotropic term can be incorporated into the modified pressure term, but does that not imply that it does contribute to momentum transfer, just under a different name? Is there a more physical interpretation of this statement that can help clarify why this is the case?

submitted by /u/GasAffectionate
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