How does antibody treatment work with COVID-19? | AskScience Blog

Pages

Friday, June 26, 2020

How does antibody treatment work with COVID-19?

How does antibody treatment work with COVID-19?


How does antibody treatment work with COVID-19?

Posted: 26 Jun 2020 01:36 AM PDT

My issue is the following: IV administered IgG mixture does seem to work in animal models and in patients. The question really is: does it work on the lung surface? If it does, how? Any papers I have seen suggested that very little IgG reaches the mucosal surface, as the FcnR transport "outside" is not very effective; IgAs use a different mechanism to reach the surface. Yet it seems like IgG based treatments work.

Do they work by limiting the viral replication outside the lung, leaving the lungs "undefended"? Wouldn't this cause serious problems with inflammation in the lungs? The other idea I can think of is that when these are administered, the integrity of the lung tissue is already compromised, so the IgGs can reach the mucosal membrane reasonably well - but this would mean the treatment is not useful as a preventive measure in mild cases when the patient is in a high-risk group.

Since I cannot find any papers discussing the mechanism of IgG therapy within the lungs I thought I would ask here.

submitted by /u/rambo77
[link] [comments]

How much deeper could the Grand Canyon get?

Posted: 25 Jun 2020 08:33 PM PDT

Would the Colorado continue to carve it out until it's down to sea level or, if there is one and it's lower, down to an aquifer?

submitted by /u/Sandman1812
[link] [comments]

What's the basis of NMR spectroscopy?

Posted: 25 Jun 2020 12:49 PM PDT

I've been doing some reading online and from what I've seen, there are two different explanations of NMR spectroscopy. One implies that the magnetic dipole moments can flip when hit by radio waves, and when they flip back, energy is emitted in the form of electromagnetic radiation. By analysing the emitted waves, we can determine their source, etc. The other explanation is that the sample is hit by a pulse, causing the dipoles to precess, and it is this precession that is used to determine the isotope in question. My question is, which of these explanations is correct? Is one a simplified version of the other? Or are both correct, and are simply different techniques for sample analysis?

submitted by /u/Shneeshnak
[link] [comments]

When was it that we discovered that gas giant are, well, made out only of gas?

Posted: 25 Jun 2020 08:48 PM PDT

I'm reading Arthur C. Clarke's "2001: A Space Odyssey" and at some point in the novel they send a probe into Jupiter (Cassini's Grand Finale-style). While it falls into the Jovian atmosphere they seem to be searching for a surface, but I thought that by then (1968), they'd already know there was none to be found (besides the solid metal core, but that they obviously knew the spacecraft couldn't reach so deeply). Either way, they never find a surface—and that wouldn't be the only fantastic prediction made in this book, to be honest.

submitted by /u/BrKo14
[link] [comments]

How do we know an asteroid hit earth 66M years ago?

Posted: 25 Jun 2020 10:17 AM PDT

Do we know that it was an astroid that caused the great extinction? Is it just a theory that hasn't been proven? I've looked up some videos and articles about it, but there's not a lot of information about it. There's some evidence about it including composition of certain sedimentary rocks, but so far I've found nothing concrete.

submitted by /u/Farkle_Griffen
[link] [comments]

What happens if you send single-frequency laser pulses through a prism?

Posted: 25 Jun 2020 10:54 AM PDT

I just learned about Fourier analysis, and how any wave that has a beginning and an end is composed of multiple different frequencies added together. With respect to light, this means that a pulse of a single frequency of light can be understood as the superposition of many different frequencies. So a theoretical laser beam that is only ever 'on' could exist as a single frequency, but once you start turning the laser on and off it ceases to be a pure sine wave, and the faster you turn it on and off the wider the spectrum of frequencies those pulses are composed of. (I think this is all true but please correct any errors I've made here).
Does that mean that if you sent pulses of single-frequency laser light through a prism, you could diffract out many different frequencies of light from that one laser frequency? Could you get a rainbow from monochromatic green light for instance, if the pulses were short enough?

submitted by /u/raimbows
[link] [comments]

Ignoring the biological ramifications, how cold would the Earth be if all the CO2 in the atmosphere disappeared?

Posted: 25 Jun 2020 12:49 PM PDT

What happens in a nuclear reaction which leads to complete change in physical and chemical properties?

Posted: 25 Jun 2020 09:15 AM PDT

example:

17O + n → 14C + α

what leads to complete change in properties of oxygen to carbon?

submitted by /u/bbro__
[link] [comments]

Why is it okay to use animal waste as crop fertilisers? Is it simply because pathogens die long before we eat the crops?

Posted: 24 Jun 2020 06:09 PM PDT

I was having a hypothetical discussion with my SO this evening (neither of us has a scientific background). I was asking why it's okay to use animal waste on fertilisers for crops which we then eat, when directly consuming animal feces would be potentially very dangerous (not to mention disgusting).

Is it simply because any pathogens from manure would die long before the crop reaches the supermarket shelf and the consumers' plates? Or is it more complicated than that?

I hope this isn't an extremely dumb question. It's something we both realised we couldn't necessarily answer even after Googling.

Many thanks in advance for any answers!

submitted by /u/Material777
[link] [comments]

No comments:

Post a Comment