AskScience AMA Series: We're Sarah Stellwagen (UMBC) and Rebecca Renberg (ARL), authors of a G3: Genes, Genomes, Genetics article on sequencing spider glue genes. They're massive - the largest has a coding sequence over 42,000 bases long, and could lead to exciting advances in biomaterials. AUA! | AskScience Blog

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Friday, June 14, 2019

AskScience AMA Series: We're Sarah Stellwagen (UMBC) and Rebecca Renberg (ARL), authors of a G3: Genes, Genomes, Genetics article on sequencing spider glue genes. They're massive - the largest has a coding sequence over 42,000 bases long, and could lead to exciting advances in biomaterials. AUA!

AskScience AMA Series: We're Sarah Stellwagen (UMBC) and Rebecca Renberg (ARL), authors of a G3: Genes, Genomes, Genetics article on sequencing spider glue genes. They're massive - the largest has a coding sequence over 42,000 bases long, and could lead to exciting advances in biomaterials. AUA!


AskScience AMA Series: We're Sarah Stellwagen (UMBC) and Rebecca Renberg (ARL), authors of a G3: Genes, Genomes, Genetics article on sequencing spider glue genes. They're massive - the largest has a coding sequence over 42,000 bases long, and could lead to exciting advances in biomaterials. AUA!

Posted: 14 Jun 2019 04:00 AM PDT

Hello, Reddit. We are Sarah Stellwagen, a biology postdoc at UMBC, and Rebecca Renberg, a research scientist at the United States Army Research Laboratory. We're excited to share how we figured out how to sequence two incredibly challenging spider glue genes for the first time, and the possibilities this opens up for science.

Spider glue is a modified version of spider silk that keeps a spider's prey stuck in its web. Unlike silk, it's a liquid both inside and outside of the spider. Because of this, spider glue might be easier to produce in the lab than silk, which could lead to major advances in biomaterials. There are so many potential applications to explore in the future, such as using it to protect crops from pests instead of using insecticides.

We'll be here to answer your questions at 11:30 a.m. EDT / 8:30 a.m. PDT

Learn more about this work at umbc.edu/go/spider-glue Read the study at https://www.g3journal.org/content/9/6/1909

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SSRIs and psychedelic empathogens (shrooms, MDMA) both increase serotonin levels in the brain. Why do empathogens cause feelings of interconnectedness and empathy when SSRIs often cause emotional blunting?

Posted: 14 Jun 2019 06:45 AM PDT

Does anticoagulant have any effect on existing blood clots in the body?

Posted: 14 Jun 2019 07:02 AM PDT

So I was watching a video that showed a blood clot trying to get through a heart valve and I got to thinking that my diet isn't the best so I could possibly have one/some trying to form. Anyways I donate plasma so and during the procces my blood is mixed with anticoagulant (sodium citrate) and spun out to remove the plasma before being returned, so my question is: does the anticoagulant have any effect on clots that have already started forming in the body or does it only stop the coagulation process from starting? I only ask because I'm wondering if there is some sort of benifit to my body from having anticoagulant in my veins.

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How does radiation (radioactive) affect electronics?

Posted: 14 Jun 2019 07:09 AM PDT

Why don’t clouds get blown apart?

Posted: 14 Jun 2019 06:07 AM PDT

How do clouds stay together in (mostly) the same shapes in high winds? Why doesn't the wind just disperse the clouds like a cloud of smoke?

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What is the difference between XVID vs H264?

Posted: 14 Jun 2019 05:40 AM PDT

I just got told that I should encode my recorded videos with h264. I have always been using xvid until now with no problems.

I use VirtualDub to encode my videos.

I encoded a 1.72GB video with both codecs on the highest quality that VirtualDub would allow.

H264 gave me a 1.1GB file

XVID gave me a 710MB file

I can't really tell the difference in quality.

What makes h264 better than xvid, if anything? And what is the main difference between the two?

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Did fungi ever engage in Endosymbiosis?

Posted: 13 Jun 2019 11:37 PM PDT

A random question that came to my mind yesterday:

As far as I know both plant and animal cells developed due to endosymbiosis, does this also apply to the cells of fungi?
If yes than what exactly happened, they can't have chloroplasts inside their cells because they are not engaging in photosynthesis but are there mitochondria inside them or something completely different but similar in function?

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Does the musicyou listen to when you are young affect what you listen to when you are older?

Posted: 14 Jun 2019 05:25 AM PDT

More specifically, if you listen and enjoy a certain song or genre when you are young does this influence the music you like later? Like if you grew up only listening to heavy metal, would you be more pre-dispositioned to like all metal, or even to not like it?

Or are there too many variables and possibility of random chance to have real evidence?

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Can the creation of monozygotic twins be artificially induced in mammals?

Posted: 14 Jun 2019 04:56 AM PDT

Asking because twin studies are very useful, so inducing this at will would probably be very helpful. Can a fertilized oocyte (a totipotent stemcell) be manipulated to create an exact copy of itself? Or is it purely coincidental?

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How does the brain isolate a sound when we focus on it?

Posted: 14 Jun 2019 04:25 AM PDT

Say you were sitting in the car listening to music and someone is talking to you. We can choose to focus on the music the person or say the engine of the car, but how does the brain isolate the sound we want to hear rather than it just all seeming like one big noise?

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What's the fundamental difference between solids, liquids and gas?

Posted: 14 Jun 2019 03:01 AM PDT

To be more precise, what makes the molecules in a liquid pack densely and stay in a container, in contrast to gas molecules which just "float around"?

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How is dating of excavated site cross-referenced?

Posted: 14 Jun 2019 02:59 AM PDT

I am looking to find materials that specifically address how multiple dating methods are being used to cross-reference and verify that excavated items indeed have the age we think they do.

Not a denier, looking for ammo to talk to deniers of the young earth creationist type.

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What is the theory that the complexity of a system is correlated to the amount of energy flowing through it?

Posted: 13 Jun 2019 01:58 PM PDT

I was listening to a history podcast, and the narrator described a theory that posited that the level of complexity is a system is proportional to the amount of energy flowing through it. In this context, I think he was describing early societies which collapsed after they lost access to resources. But, if I remember correctly, the theory applied to all types of systems, not just social systems. I'm intrigued by the idea, and want to read more about it, but I can't remember who the originator of the theory was, or even which podcast I was listening to.

Who's theory is this? Where can I learn more about it?

BTW, I chose "mathematics" for the flair of this post, but I don't really know what branch of science this theory belongs too.

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Does watching horror movies make you less fearful of “scary” things in real life?

Posted: 14 Jun 2019 01:48 AM PDT

When I toss a tennis racquet, ping pong paddle, or my shoe in the air almost perfectly vertically, it does not just flip. It does a twist as well. Can someone explain this phenomenon?

Posted: 13 Jun 2019 12:21 PM PDT

What's the difference between a low fever and a high fever? Does your body just know to set the thermostat higher for certain illnesses?

Posted: 13 Jun 2019 12:00 PM PDT

How do we get a sense of "current events" in the cosmos?

Posted: 13 Jun 2019 08:39 PM PDT

I just wanna throw this out there... I dont know much about space. Anyways...

Let's just say a satellite takes a photograph of an exoplanet from 10 light years away. That should mean that the image is made up of light that is 10 years old. How do we know that this exoplanet is still there? A meteor could have destroyed it 2 years prior to the photograph being taken and the light from the explosion would still have another 8 years to travel before we saw it. Or do we have a way of knowing for sure that planet is really there, at that moment the photograph is taken?

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How does carbon capture technology work? Would removing carbon from the atmosphere reverse the effects of climate change or just keep them from getting worse?

Posted: 13 Jun 2019 05:52 AM PDT

Can bleach disinfect ebola?

Posted: 13 Jun 2019 11:44 AM PDT

I was watching Hot Zone on NatGeo recently, and i in it they use bleach to disinfect everything that has been contaminated, is this actually true? And if yes, do they use the same store bought bleach or is it some special powerful ebola killer bleach?

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