AskScience AMA Series: I'm Adam Boyko, canine geneticist at Cornell and founder of dog DNA testing company, Embark. We're looking to find the genes underlying all kinds of dog traits and diseases and just discovered the mutation for blue eyes in Huskies. AMA! | AskScience Blog

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Monday, October 22, 2018

AskScience AMA Series: I'm Adam Boyko, canine geneticist at Cornell and founder of dog DNA testing company, Embark. We're looking to find the genes underlying all kinds of dog traits and diseases and just discovered the mutation for blue eyes in Huskies. AMA!

AskScience AMA Series: I'm Adam Boyko, canine geneticist at Cornell and founder of dog DNA testing company, Embark. We're looking to find the genes underlying all kinds of dog traits and diseases and just discovered the mutation for blue eyes in Huskies. AMA!


AskScience AMA Series: I'm Adam Boyko, canine geneticist at Cornell and founder of dog DNA testing company, Embark. We're looking to find the genes underlying all kinds of dog traits and diseases and just discovered the mutation for blue eyes in Huskies. AMA!

Posted: 22 Oct 2018 04:00 AM PDT

Personal genomics is a reality now in humans, with 8 million people expected to buy direct-to-consumer kits like 23andme and AncestryDNA this year, and more and more doctors using genetic testing to diagnose disease and determine proper treatment. Not only does this improve health outcomes, it also represents a trove of data that has advanced human genetic research and led to new discoveries.

What about dogs? My lab at Cornell University focuses on canine genomics, especially the genetic basis of canine traits and disease and the evolutionary history of dogs. We were always a bit in awe of the sample sizes in human genetic studies (in part from more government funding but also in part to the millions of people willing to buy their own DNA kits and volunteer their data to science). As a spin-off of our work on dogs, my brother and I founded Embark Veterinary, a company focused on bringing the personal genomics revolution to dogs.

Embark's team of scientists and veterinarians can pore over your dog's genome (or at least 200,000 markers of it) to decipher genetic risks, breed mix, inbreeding, and genetic traits. Owners can also participate in scientific research by filling out surveys about their dog, enabling canine geneticists to make new discoveries. Our first new discovery, the genetic basis of blue eyes in Siberian Huskies, was published this month in PLOS Genetics.

I'll be answering questions starting around 2:30 ET (1830 GMT), so unleash your questions about genomics, dogs, field work, start-ups or academia and AMA!

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How do lakes deep underground maintain an ecosystem with no energy input from the Sun?

Posted: 21 Oct 2018 06:35 AM PDT

Why does Sweden have temperate climate while on the other side in Canada they have polar climate?

Posted: 22 Oct 2018 07:47 AM PDT

What would be the effect of showering in pure water?

Posted: 22 Oct 2018 08:32 AM PDT

Hard water is known to dry out the skin but what would pure water do?

submitted by /u/PHealthy
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What findings exist on studies made on the effect of “screen time” (TV, tablets, etc.) in cognitive development in children?

Posted: 21 Oct 2018 10:23 PM PDT

What are the advantages/disadvantages of a ternary computer vs a binary computer? Why are almost all modern computer binary computers?

Posted: 21 Oct 2018 06:38 PM PDT

What causes tall cliff shorelines?

Posted: 22 Oct 2018 07:23 AM PDT

This one in Ireland for instance

imagine finally finding land, after wandering aimlessly in the sea only to realize it's practically impenetrable

submitted by /u/savvyfuck
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Does Neurodegeneration occur in unsupervised Artificial Neural Networks?

Posted: 21 Oct 2018 10:32 AM PDT

If a bilingual person were to experience full-on retrograde amnesia, would they retain the ability to speak both of their languages?

Posted: 21 Oct 2018 04:34 PM PDT

When creating yoghurt, recipes call for the starting temperature to be 110-115F. Will a lower starting temperature impact the outcome?

Posted: 21 Oct 2018 07:51 PM PDT

Most recipes I have found are fairly diligent about standing by with a thermometer to add the starter culture once the temperature hits 110-115F. The temperature is then maintained at that temperature for some time. If the starter culture that is being added is at room temperature, and the pasteurized milk is allowed to cool to below 110F, then the entire business is heated back up to 110-115F, what are the consequences from the perspective of the bacteria? Does the few minutes that the milk spends getting back up to temperature really make a difference? I imagine that the bigger concern is that you add the culture too early and they are killed by the high temperatures.

submitted by /u/gradygradygrady
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What’s the process behind determining an organism’s species by examining its DNA?

Posted: 21 Oct 2018 07:56 PM PDT

Suppose you have an organism and collect some DNA to determine its species. Now what? What technology is required? How is it done? What is the process called? What is used as a reference guide to compare its DNA? Whose job is it to even do something like this? And so forth.

submitted by /u/MrPancake101
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How do astronomers know how old a star is/how old they can get?

Posted: 21 Oct 2018 03:56 PM PDT

What are the main differences between the human and the brain of apes?

Posted: 21 Oct 2018 07:07 AM PDT

If you cut open up the skull of a human and an ape, what fundamental differences you can observe?

submitted by /u/ManagerOfLove
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Endothelial cell’s access to Oxygen?

Posted: 21 Oct 2018 01:34 PM PDT

Since there is no oxygen in the red blood cells in veins, how do the cells that make up the veins themselves actually get the oxygen they require to function?

I assume that the cells in arteries can just take it straight from the blood.

submitted by /u/charliebewsey7
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Do materials that conduct heat better than others melt more quickly?

Posted: 21 Oct 2018 02:59 PM PDT

Say we have two metals. Metal A conducts heat better than B. Will A melt first?

submitted by /u/HMS-Dreadnought
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With advances in immunology and medicine, how has our immune system changed over the last hundred years?

Posted: 21 Oct 2018 01:09 PM PDT

You know when you can't sleep but your trying to so you lay there with your eyes closed? Does that time spent awake but trying to sleep help you in any way or is it wasted time?

Posted: 20 Oct 2018 05:58 PM PDT

What criteria are used to judge an animal’s intelligence?

Posted: 21 Oct 2018 10:41 AM PDT

Why can’t Windows uninstall more than one program at the same time?

Posted: 21 Oct 2018 01:02 PM PDT

When you have a rash that is an allergic reaction to something you ingested, what makes it “decide” where on your body to show up? Why doesn’t it just show up everywhere on your body?

Posted: 20 Oct 2018 07:12 PM PDT

Why is glass translucent/transparent? Is it a molecular arrangement thing? Is all clear matter clear for the same reason, such as water and diamond?

Posted: 20 Oct 2018 05:50 PM PDT

How do you determine if an animal is from a different species ?

Posted: 21 Oct 2018 09:36 AM PDT

How do biologists determine if an animal , hybrid between two species, is not from a new different species. Is it just that if it's sterile , it cannot be a new species ? And also , how do they know that the animal is sterile?

submitted by /u/wolfgang852
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