American Chemical Society AMA: I am Gerry Wright, Director of the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University and Associate Editor of ACS Infectious Diseases. Ask me anything about antibiotic resistance and antibiotic discovery. | AskScience Blog

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Tuesday, May 24, 2016

American Chemical Society AMA: I am Gerry Wright, Director of the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University and Associate Editor of ACS Infectious Diseases. Ask me anything about antibiotic resistance and antibiotic discovery.

American Chemical Society AMA: I am Gerry Wright, Director of the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University and Associate Editor of ACS Infectious Diseases. Ask me anything about antibiotic resistance and antibiotic discovery.


American Chemical Society AMA: I am Gerry Wright, Director of the Michael G. DeGroote Institute for Infectious Disease Research at McMaster University and Associate Editor of ACS Infectious Diseases. Ask me anything about antibiotic resistance and antibiotic discovery.

Posted: 24 May 2016 04:46 AM PDT

Hi Reddit! I am a Professor of Biochemistry and Biomedical Sciences at McMaster Univeristy and Director of the Michael G. DeGroote Institute for Infectious Disease Research (http://mcmasteriidr.ca/). I have been working on antibiotic resistance and discovery for over 25 years. My lab uses a combination of chemistry, microbiology, biochemistry and genomics to understand how antibiotics work, along with exploring mechanisms and evolution of resistance. We use this information to learn how to find new antibiotics and alternatives to antibiotics.

I am also an Associate Editor of the journal ACS Infectious Diseases (http://pubs.acs.org/page/aidcbc/editors.html), a publication that highlights how chemistry sheds light on and helps in the fight against pathogens.

I am happy to answer any questions you may have on antibiotic resistance and discovery.

I will be back at 1 pm ET, ask anything.

submitted by /u/AmerChemSocietyAMA
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Why did heavy-lift launch vehicles use spherical fuel tanks instead of cylindrical ones?

Posted: 23 May 2016 09:32 AM PDT

If you look at the cutaways of the Saturn V and N-1 in this webpage you can see that the fuel tanks taper away from the inner sides of the spaceship due to their spherical nature. Why didn't they use the full space available to them?

submitted by /u/8BandComp
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Can space-time warp in such a way as to allow me to start a journey and then return as my mirror image?

Posted: 24 May 2016 02:29 AM PDT

How do we find out if electrons are not elementary?

Posted: 23 May 2016 10:35 AM PDT

What experiments can or have been done to confirm this being true or false?

submitted by /u/blueredscreen
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Is there a continuous version of product, like integrals for sums?

Posted: 23 May 2016 11:36 AM PDT

Are there weird Karman Lines on other planets?

Posted: 23 May 2016 10:27 AM PDT

The Karman Line is about 100km on Earth, and that's where in order for an aircraft to generate lift against the atmosphere you need to be travelling faster than what it takes to maintain stable orbit.

I'm having a hard time turning this over in my head for places like Jupiter, Venus and Titan.

submitted by /u/accidentallybrill
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Are the three spatial dimensions actually one dimension, represented by three vectors? Are the three dimensions actually "separate"?

Posted: 23 May 2016 10:07 AM PDT

While we represent position in three dimensional space using three coordinates, it occurred to me that the universe may not have a discrete x, y, and z axis. If these dimensions can be mixed in to each other depending on your reference frame, are they really a separate phenomenon?

submitted by /u/light24bulbs
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How does citric acid stop oxidation?

Posted: 24 May 2016 03:12 AM PDT

Why are images of the same width and height so different in file size?

Posted: 24 May 2016 04:08 AM PDT

Whenever I create some image in Photoshop and save it (lets say 1920x1080px) it's like 1MB file size. When I blur the entire image it's suddenly only 100KB.

Why is there a difference in file size, doesn't the image have to 'remember' which color what pixel is, regardless of how sharp/blurred or clean/messy an image is? It still has the same amount of pixels.

submitted by /u/Conjomb
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What are nano-photovoltaic cells?

Posted: 24 May 2016 03:12 AM PDT

I am studying a little about research ongoing in Solar energy. It seems that research in nano-PV has increased over the time.

Please shed some lights on efficiency too, how are they doing against our current PV technology? better or worse? As I am no expert in this domain please throw away any information you have. I would really appreciate it.

submitted by /u/siez_
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Is there a complete topographic dataset of Earth?

Posted: 24 May 2016 02:53 AM PDT

As the title says, I am searching for complete topographic data of the entire planet. SRTM is the closest I could find so far, but it covers only about 80% of the area of the planet. Is there a way to get more of the data?

submitted by /u/notsofunnynowehh
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How does a planet's orbit change as one of the suns in a binary-sun solar system starts do 'die'?

Posted: 24 May 2016 02:51 AM PDT

Given a solar system with a binary sun, where one of the suns is noticeably smaller than the other; given that such a system has only one planet with its companion moon.

The smaller sun starts to die. Will the orbit of the lone planet expand or contract? Will that planet's year get longer or shorter as the sun dies off?

Thanks!

submitted by /u/DrVialgo
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So when two black holes collide they form a bigger one, but what if a black hole were to collide with a white hole?

Posted: 24 May 2016 03:24 AM PDT

also what if this black hole is connected to that specific 'white hole'

submitted by /u/AgilityBobblehead
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Are the number of electrons equal to the number of protons in the universe?

Posted: 23 May 2016 09:22 PM PDT

Why are 5 independent slip systems needed for arbitrary deformation?

Posted: 23 May 2016 09:52 AM PDT

So the Von Mises Criterion says we need 5 active slip systems, but why are 3 not enough for a 3 dimensional object??

submitted by /u/MmmmmmmmDonuts
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What really causes Hematite stones to crack or break?

Posted: 23 May 2016 06:30 PM PDT

When Googling the question, all that comes up is the new age answer, "that it absorbs negativity."

What really causes hematite to break after sitting around for a few years?

submitted by /u/geotagger
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Are there any math problems that even a computer could not solve?

Posted: 23 May 2016 03:10 PM PDT

Edit: To those wondering what I mean by "math problem," I simply mean any problem that involves math, or basic logic. Does that makes sense?

submitted by /u/rsmtirish
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Can sound frequencies break anything?

Posted: 23 May 2016 08:46 AM PDT

So when someone sings loud enough to break glass they're matching the frequency of the glass. And if everything in life has a frequency does that mean that if the specific frequency of any substance is matched it will break?

submitted by /u/relljr
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Why is such a large portion of our star systems mass concentrated at the Sun?

Posted: 23 May 2016 09:15 AM PDT

The Sun contains about 99.9% of all the mass in our star system, but in some other star systems the mass is spread enough to form orbiting brown dwarfs, binary stars and what not. What is it in a star systems formation that causes them to have such huge differences between each other on mass distribution?

submitted by /u/empire314
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Are there any pathogenic (to humans) archaea?

Posted: 23 May 2016 07:44 AM PDT

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