Pages

Tuesday, June 9, 2020

Why do we hear about breakthroughs in cancer treatment only to never see them again?

Why do we hear about breakthroughs in cancer treatment only to never see them again?


Why do we hear about breakthroughs in cancer treatment only to never see them again?

Posted: 08 Jun 2020 04:35 PM PDT

I often see articles about breakthroughs in eradicating cancer, only to never hear about them again after the initial excitement. I have a few questions:

  1. Is it exaggeration or misunderstanding on the part of the scientists about the drugs' effectiveness, or something else? It makes me skeptical about new developments and the validity of the media's excitement. It can seem as though the media is using people's hopes for a cure to get revenue.

  2. While I know there have been great strides in the past few decades, how can we discern what is legitimate and what is superficial when we see these stories?

  3. What are the major hurdles to actually "curing" cancer universally?

Here are a few examples of "breakthrough" articles and research going back to 2009, if you're interested:

2020: https://www.google.com/amp/s/www.bbc.com/news/amp/health-51182451

2019: https://www.sciencedaily.com/releases/2019/06/190604084838.htm

2017: https://www.google.com/amp/s/time.com/4895010/cancers-newest-miracle-cure/%3famp=true

2014: https://www.sciencedaily.com/releases/2014/03/140325102705.htm

2013: https://www.cancerresearch.org/blog/december-2013/cancer-immunotherapy-named-2013-breakthrough-of-the-year

2009: http://www.cnn.com/2009/HEALTH/12/17/cancer.research.breakthrough.genetic/index.html

TL;DR Why do we see stories about breakthroughs in cancer research? How can we know what to be legitimately excited about? Why haven't we found a universal treatment or cure yet?

submitted by /u/throwaway63257
[link] [comments]

If breaking the sound barrier causes a sonic boom, what would breaking the light speed barrier do?

Posted: 08 Jun 2020 08:50 AM PDT

How does a computer know when to shutdown itself due to overheat?

Posted: 09 Jun 2020 08:25 AM PDT

Like for instance, when the CPU gets to hot, what actually happen? I assume the motherboard reads the temperatures sensors and send a trigger warning to the PSU to cut the power if it's above a threshold, something like that?

Also when it comes to the GPU, can an overheat cause the PC to shutdown or it's only translated with even bigger artefacts all over the screen?

Thanks in advance for the help.

submitted by /u/qS3ra
[link] [comments]

Can you kill a virus?

Posted: 09 Jun 2020 09:03 AM PDT

Am not sure if my question qualifies to be here but I really hope someone gets me an answer, be it a relative one... If viruses have no cell, and are basically classified as non-living, can they die? WHO says small pox virus has been eliminated but I don't understand how, given that viruses have a way to stay in a host body inactive for many years... So how do you eliminate something that can "live without being alive"? Thank you

submitted by /u/LordZepha
[link] [comments]

Once there's a COVID vaccine, what percentage of the population must be vaccinated to reach herd immunity? How long would this take?

Posted: 08 Jun 2020 08:30 PM PDT

What causes the symptoms of pox diseases?

Posted: 09 Jun 2020 03:19 AM PDT

Why is it that diseases like smallpox and chickenpox cause blisters, postules and papules over the body? Is it an immune response? An evolutionary response so the virus spreads more easily?

I suppose this question extends to other diseases which cause papules, like the plague.

submitted by /u/tickera
[link] [comments]

Why doesn't the voltage in a wall socket drop, when I plug a device in?

Posted: 09 Jun 2020 09:03 AM PDT

When I connect a battery to a load, bascially the voltage of that battery goes slowly to zero, because the electrical charge is evening out and also the resistance of the load lowers the voltage from the previous state of no-load.
I assume this would also happen in a wall socket, since I would change from no-load to load, so it would lower the resistance of the electric circuit.
If that is the case: Why does the socket voltage remain stable?

Since I am an communications engineer, I have basic kowledge of electronics, power electronics and power enigneering, so you can be very technical in your answer, but since I haven't used this knowledge since years, I can't answer it myself.

submitted by /u/suuuupercroc994
[link] [comments]

How did Newtonian gravity and general relativity's predictions of the bending of light due to gravity differ?

Posted: 09 Jun 2020 07:01 AM PDT

Like general relativity, Newtonian gravity predicts that the presence of the sun will bend star light (according to this Vox video), so that when observing stars around the sun during an eclipse, you will observe some displacement. General relativity predicts a different amount of displacement, hence the famous photo proving Einstein's theory. Why did the two theories predict different amounts of displacement?

submitted by /u/harumphfrog
[link] [comments]

Are a symptomatic and pre symptomatic considered different things?

Posted: 09 Jun 2020 08:54 AM PDT

I'm reading a statement that says that at least according to WHO asymptomatic spread of Covid is rare but possible. But I'm not sure if someone who later developed symptoms is considered an a symptomatic case or not.

submitted by /u/maiqthetrue
[link] [comments]

Atomspheric lapse rate applied to solids?

Posted: 09 Jun 2020 04:43 AM PDT

The lapse rate which is proportional to g/cp (gravity/ heat capacity) means that the higher you go up in the atmosphere, the cooler it gets. Think white snow capped mountains.

Does this lapse rate formula also apply to solids and explains why it gets hot down the bottom of mines?

Looking at the wikipedia article and derivation there doesn't seem to be anything particular to gases.

Wikipedia Lapse Rate

Applying the lapse rate formula -9.8/Cp to a deep gold mine gives a similar result.

-9.8/800*4000m= 49oC temperature rise

800 is rough Cp for rock 4000m Mponeng Gold mine depth 66oC is temperature at bottom of mine

Gold mine

And average annual temperature is 18.2oC Gauteng province

49+18=67oC

The above is fairly close match so the theory doesn't sound unreasonable to me.

submitted by /u/Tarsal26
[link] [comments]

Do monkeys or other apes get chapped lips?

Posted: 08 Jun 2020 09:00 PM PDT

Why are moles (I think Nevi is the correct term) so dangerous?

Posted: 09 Jun 2020 06:52 AM PDT

Since a kid that my parents and doctors tell me to be cautious around the sun and protect my skin, especially any mole. And I know a lot of people that had moles removed without them being cancerous. What differenciates them from normal skin and why are they so dangerous? Are red moles dangerous as well?

submitted by /u/MrDrunkCat
[link] [comments]

In terms of evolution which came first ribosomes or proteins ?

Posted: 09 Jun 2020 05:20 AM PDT

Do nerve agents always work by blocking acetylcholinesterase?

Posted: 09 Jun 2020 05:03 AM PDT

After some research I've found that most nerve agents seem to work this way but is this the only way they could work?

submitted by /u/acornstudent777
[link] [comments]

Why does your skin itch when you get into a really hot bath?

Posted: 08 Jun 2020 09:16 PM PDT

Google only shows me reasons for why you itch after a hot shower, but my skin itches like crazy the first few seconds after getting into a super hot bath, and I still haven't found anything on why it does.

submitted by /u/astasodope
[link] [comments]

If fossil fuels once were a part of the carbon cycle, why is it bad when we emit the carbon back into the air?

Posted: 08 Jun 2020 10:44 PM PDT

Fossil fuels are, well, fossils. And therefore, it was something living that died and didn't decompose. But was the carbon a part of the animal or is it oils from inside the Earth? Why is it bad for the planet to emit carbon dioxide when that level once was a totally normal part of the ecosystems?

submitted by /u/heliumlantan
[link] [comments]

Does the influenza virus affect cell size?

Posted: 08 Jun 2020 03:56 PM PDT

For instance, does the cell swell or shrink after infection? I can't find anything online

submitted by /u/JMoneyG0208
[link] [comments]

Why doesn’t California get tsunamis?

Posted: 08 Jun 2020 09:01 AM PDT

Is it possible to have a region of a gravitational field with non zero curl?

Posted: 08 Jun 2020 02:53 PM PDT

Yes curl as in mathematical curl in the vector field. In what situation(s) would this happen, if it is possible?

submitted by /u/Deleizera
[link] [comments]

In turbulent fluid dynamics, why does the isotropic part of Reynolds stress tensor not transfer momentum?

Posted: 08 Jun 2020 02:12 PM PDT

I have come across the statement in an online lecture, "Only the anisotropic term is effective in turbulent transport of momentum." I understand that the isotropic term can be incorporated into the modified pressure term, but does that not imply that it does contribute to momentum transfer, just under a different name? Is there a more physical interpretation of this statement that can help clarify why this is the case?

submitted by /u/GasAffectionate
[link] [comments]

Monday, June 8, 2020

AskScience AMA Series: We are statisticians in cancer research, sports analytics, data journalism, and more, here to answer your questions about how statistics opens doors for exciting careers. Ask us anything!

AskScience AMA Series: We are statisticians in cancer research, sports analytics, data journalism, and more, here to answer your questions about how statistics opens doors for exciting careers. Ask us anything!


AskScience AMA Series: We are statisticians in cancer research, sports analytics, data journalism, and more, here to answer your questions about how statistics opens doors for exciting careers. Ask us anything!

Posted: 08 Jun 2020 04:00 AM PDT

Statistics isn't what you think it is! With a career in statistics, the science of learning from data, you can change the world, have fun, satisfy curiosity and make a good salary. Demand for statisticians is on the rise, and careers in statistics are consistently on best jobs lists. Best of all, statistics applies to just about any field, so you can apply it to a wide range of personal passions. Just ask our real-life statisticians to learn more about the opportunities!

The panelists include:

  • Olivia Angiuli - Research scientist at SignalFire; former Ph.D. student in statistics at UC Berkeley; former data scientist at Quora
  • Rafael Irizarry - Applied statistician performing cancer research as professor and chair of the Department of Data Science at Dana-Farber Cancer Institute, professor at Harvard University, and co-founder of SimplyStatistics.org
  • Sheldon Jacobson - Founder professor of computer science, founding director of the Institute for Computational Redistricting, founding director of the Bed Time Research Institute, and founder of Bracket Odds at the University of Illinois at Urbana-Champaign Research Institute, and founder of Bracket Odds at the University of Illinois at Urbana-Champaign
  • Liberty Vittert - TV, radio and print news contributor (including BBC, Fox News Channel, Newsweek and more), professor of the practice of data science at the Olin Business School at the Washington University; associate editor for the Harvard Data Science Review, board member of board of USA for the UN Refugee Agency (UNHCR) and the HIVE.
  • Nathan Yau - Author of Visualize This and Data Points, and founder of FlowingData.com.

We will be available at noot ET (16 UT), ask us anything!

Username: ThisIsStatisticsASA

submitted by /u/AskScienceModerator
[link] [comments]

How does the energy of a nuclear fusion reactor scale according to its size?

Posted: 07 Jun 2020 11:19 PM PDT

Does it scale according to volume? For example, if you have a reactor that fits a volume X of hydrogen, and another that fits 10X, would the energy generated by the second be 10 times the energy produced by the first one? Or does it scale exponentially or by some other factor? (assuming the reactors have the same efficiency)

submitted by /u/Deleizera
[link] [comments]

Do our body recycle "dead" viruses?

Posted: 08 Jun 2020 03:46 AM PDT

What actually happens to a virus when our immune system kills it?
Does our body just flush it or does it "recycle" the amino acids and proteins of it?

submitted by /u/zombycatoutofpocket
[link] [comments]

What are the implications of neutrons having a magnetic moment? Can they be magnetically confined/guided? How do they interact with external magnetic fields? Can they have their own magnetic fields, and how would that field look? Would it be able to induce currents in nearby conductors?

Posted: 07 Jun 2020 05:56 PM PDT

How successful is social work and assistance in reducing poverty in the long term?

Posted: 08 Jun 2020 04:12 AM PDT

What is the effectiveness of social workers and assistance in reducing poverty rates

Hi everyone i want to ask social sciences what the effectiveness of reducing poverty is.

Is this a dream or is there evidence to back it up

submitted by /u/dramasutra2020
[link] [comments]

Blasius Boundary Layer approximations still apply if turbulent at trailing edge?

Posted: 08 Jun 2020 07:45 AM PDT

I was looking up the blasius solutions, but I can't think of how to generalise the Blasius approximations if the fluid boundary layer only transitions to turbulence(approximately) at the trailing edge. As someone with little knowledge on this subject, what I think is blasius approximations for skin friction coefficient should still apply, as past the trailing edge where turbulence occurs does not have "skin" to apply friction. However, I do not know how to show this rigorously.

submitted by /u/FaerNC
[link] [comments]

What's the difference between Electron Microscopy and Cryo-Electron Microscopy?

Posted: 08 Jun 2020 06:47 AM PDT

Are there planet systems that orbit other objects?

Posted: 08 Jun 2020 06:14 AM PDT

I was wondering if there are systems that have planets which orbit other objects.

For example if there is a system where other planets display similar behaviour to a solar system where there are a few planets somewhat close to each other that orbit an object, but instead of having a star as the centre it's something else? Maybe a bigger planet with enough gravitational pull (would that make the other planets its moons and the main planet just a rogue planet?) to be considered its own system.

If there are, what are they called?

submitted by /u/ninboja
[link] [comments]

Do animals need physical touch the same way humans do? Can animals be 'touch starved'?

Posted: 07 Jun 2020 11:58 PM PDT

Do all breathing animals yawn? What determines whether species yawn?

Posted: 08 Jun 2020 05:45 AM PDT

A dumb question about roundabouts and rods. What would happen?

Posted: 08 Jun 2020 05:43 AM PDT

Lets say someone had a really long rod and a roundabout and they made the roundabout spin at a speed close to the speed of light. Then they held the rod out away from the roundabout whilst on the roundabout. The other end of the rod would be moving around the roundabout at a faster speed than the speed at which the roundabout is spinning. Since the roundabout is spinning at a speed close to the speed of light one would think that the other end of the rod would be moving faster than the speed of light but this is not possible. So what would happen to the rod and the roundabout assuming that there is no atmosphere, the rod is indestructible and the person holding the rod is incredibly strong and and is stuck to the roundabout?

submitted by /u/OliTheOK
[link] [comments]

Is there any significance that water has a density near the round number of 1000 kg/m ^3?

Posted: 07 Jun 2020 10:05 PM PDT

How do surgical lasers for cutting tissue differ in penetration depth/delivery from lasers meant for over the skin radiation procedures?

Posted: 08 Jun 2020 05:04 AM PDT

I am thinking for example dental lasers for cutting gums, or lasers used in surgery for cutting. Does their radiation and the temperature change only reach the nearby area they scorch? Do their effects reach any surrounding tissue other than the area they "sear"?

And on the other side lasers used in dermatology that don't directly cut the skin, but somehow work on the deeper layers.

One example are the YAG lasers which seem to be used for both things, some sear the tissue directly and some don't...

submitted by /u/AlienUtterings
[link] [comments]

What skin flies (or insencts similar to flies as an anatomy) have ?

Posted: 08 Jun 2020 03:43 AM PDT

For instance, ants,cockroachs etc. have chitin. So what is it for flies ?

submitted by /u/Rhibboleth
[link] [comments]

Why do you see a sort of “motion blur” in real life?

Posted: 08 Jun 2020 03:28 AM PDT

Sounds kinda stupid but I couldn't find an answer on google as "motion blur" will always turn up something about photography. Basically, what I'm curious about is the phenomenon when there's a dim source of light in a dark setting (like using a phone in a dark room), any fast movement always translates to a weird trail of light behind the source. Is the light being momentarily burnt into your retina or is something else happening?

submitted by /u/throwaway47307482
[link] [comments]

How much of the payload in a nuclear device is actually fissioned/fusioned upon detonation?

Posted: 07 Jun 2020 09:12 PM PDT

I assume that the few nanoseconds after detonation of a nuclear device would instantly spill the payload out into a larger volume (I could definitely be wrong here). For how long is the payload still fissioning/fusioning after detonation? I'm curious to know how much mass is released as energy.

submitted by /u/Cacophonously
[link] [comments]

Why does yelling damage your larynx?

Posted: 07 Jun 2020 08:44 PM PDT

I tried to find a more specific answer with a search, but instead of telling me why... all of the results simply talked about the fact that it does.

submitted by /u/nacmar
[link] [comments]

Why are galaxy arms stable?

Posted: 07 Jun 2020 08:16 PM PDT

I know that galaxy arms are essentially density waves with stars moving in and out of the wave as they orbit around the galaxy centre. This part makes sense to me. The arms are brighter than the areas between them, and arms being brighter means that there are more stars and is therefore more dense. However, I don't understand how this density wave is stable.

A common analogy to explain galaxy arms is cars slowing down to look at an accident on the side of the road. There is always a clump of cars near the accident, but cars constantly move into and out of the clump. I don't like this analogy because I would think that stars would speed up, not slow down, as they approach the density wave because of the gravitational attraction between that star and the density wave. Similarly, I would think that a star moving out of the density wave would slow down for the same reason. If this were the case, I would expect galaxy arms to quickly fade into a more uniform disc, but we know this to not be the case. What am I missing here?

submitted by /u/JamesonLKJ
[link] [comments]

Are there different varieties of viruses under the COVID-19 virus?

Posted: 07 Jun 2020 04:48 PM PDT

When I see the statistics, in some regions, the mortality rate is high and in other regions, it's low. What's the reason behind this?

submitted by /u/Ugly247King
[link] [comments]

why is it recommended to tilt a glass ketchup bottle 45 degrees instead of 90 degrees to pour the ketchup out?

Posted: 07 Jun 2020 07:58 PM PDT

Sunday, June 7, 2020

Where in an atom exactly is a nucleus located? Is it in the centre or does its location vary from time to time?

Where in an atom exactly is a nucleus located? Is it in the centre or does its location vary from time to time?


Where in an atom exactly is a nucleus located? Is it in the centre or does its location vary from time to time?

Posted: 07 Jun 2020 06:16 AM PDT

Why are whales so much bigger than other animals?

Posted: 07 Jun 2020 06:35 AM PDT

I'm watching a documentary and although I knew they're bigger, I'm not sure why they're so much bigger and how they can be sustained as animals whereas other bigger animals couldn't. Also why do they mainly feed on something so small e.g. crill

submitted by /u/whynotnemesis
[link] [comments]

There is a lot of talks recently about herd immunity. However, I read that smallpox just killed 400'000 people/year before the vaccine, even with strategies like inoculation. Why natural herd immunity didn' work? Why would the novel coronavirus be any different?

Posted: 06 Jun 2020 09:24 AM PDT

Does recovering from COVID-19 give less or more resistance than a theoretical vaccine would?

Posted: 06 Jun 2020 11:01 PM PDT

To my understanding, it is unclear exactly how much immunity being infected with COVID-19 and recovering gives you. I'm always seeing warnings that even if you get sick, have symptoms, and receive a positive test, you should not assume you are immune after recovery, and should still take the same precautions as everyone else. And there are confirmed cases of people getting it more than once.

This being the case, what does this say about the efficacy of a vaccine? If it turns out that full-on bedridden infection doesn't provide you with much or any protection, would a vaccine do any better?

submitted by /u/Lucca01
[link] [comments]

The latest "Kurzgesagt" video starts with: "The sun, round and smooth and peaceful." How smooth is the sun?

Posted: 07 Jun 2020 07:17 AM PDT

I've seen comparisons between the silicone kg and the earth, if either were shrunk or blown up to the others size, but never about the sun.

Is it smooth? Is it's surface relatively even (like the seas)?

submitted by /u/Schwitter
[link] [comments]

Why doesn't malaria spread from endemic to non-endemic regions of the world?

Posted: 06 Jun 2020 01:31 PM PDT

Malaria is transmitted through mosquitos. If an infected mosquito bites a person, then that person gets malaria. If another mosquito bites that person post-infection, then the mosquito gets the parasite and can spread it to other people.

Here's what I don't get: millions of people in the Western world (and in other areas that don't have malaria) travel to sub-Saharan Africa and other endemic regions every year. Surely there'd be at least a few cases a year of somebody getting infected, going back home (e.g. to a country like Canada) before developing symptoms, other mosquitos (in Canada) biting that person, and then those mosquitos spreading it around the population. Why does this never happen? I feel like I'm missing something fundamental, but I don't know what.

Thanks!

submitted by /u/www_earthlings_com
[link] [comments]

Did the US have significant hosptial strain that led to additional deaths during the Covid crisis?

Posted: 07 Jun 2020 12:09 AM PDT

Tonight I was at a dinner and someone said there was never any real strain on hospitals in the US during the worst of the crisis, that deaths were solely the result of Covid symptoms, and that hospitals' lack of supplies or strain never caused an increase in deaths.

I was pretty certain this wasn't true but didn't have any hard evidence. All I could really remember (after drinks) were qualitative headlines citing strain, videos of stressed out doctors in NY, and the ubiquitous bell curve graphs showing hospital strain in rapid onset epidemic scenarios.

I was pretty sure that people had died without proper treatment and lack of ventilators, etc., but the individual kept stating "we had beds for everyone, it was never an issue here. Italy maybe, but the US always had enough beds and supplies."

Just wanted to get some additonal facts on this. I appreciate any insight. Thanks in advance.

submitted by /u/APoliticalQuestion
[link] [comments]

What does "discovering an antibody" imply?

Posted: 07 Jun 2020 01:19 AM PDT

With the covid-19 epidemic going on, there is a lot of talk about "discovering" or "finding" antibodies. Could anyone shed a little light on exactly what this implies, for someone with little biology knowledge?

What I gather is happening, is that some people, or even animals, produce particular peptides/proteins that has a tendency to bind to the virus particles, thus stopping the virus from entering cells. But that is very vague, and I have some particular questions around this:

  • Does the antibody have to be a peptide/protein? Or could it for example be a complex sugar?

  • Are the antibodies always produced as part of a person's or animal's normal immune system? Or could they come from completely random sources - e.g. could, say, haemoglobin just magically happen to inhibit a virus?

  • Are we looking for potential antibodies only in humans, or also animals/plants? What determines where we look?

  • Once you've discovered an antibody, how do you get it into patients? Is it as simple as genetically engineering a yeast cell to produce the antibody, and then injecting said antibody into patients' blood? I obviously assume it's much more complicated than that, so would be interested to hear the key challenges.

submitted by /u/funklute
[link] [comments]

Almost everyone knows having excess body fat is harmful to our health since it leads to obesity and a myriad of other conditions. But does having too little body fat (both subcutaneous and visceral) negatively impact our health as well?

Posted: 06 Jun 2020 08:56 AM PDT

(Title)

submitted by /u/berrin899
[link] [comments]

How exactly do astronomers calculate the trajectory of an asteroid as it comes close to Earth?

Posted: 06 Jun 2020 06:20 PM PDT

In just short of a couple of hours, Asteroid 2002 NN4 will come close to Earth (approx. 5M kilometers). How do they predict the exact distance? What if they're a little off and the asteroid actually does make contact with Earth? I'm a bit of a worry-wort, so forgive me if I sound a bit skeptical. I just want the facts from a professional.

submitted by /u/GreenSaltMedia
[link] [comments]

When you get a nose bleed, where is the blood coming from?

Posted: 06 Jun 2020 06:13 PM PDT

If I had a light source that only put out 540 no radiation (green light) and no other radiation would focusing that light produce heat on a target?

Posted: 06 Jun 2020 10:07 AM PDT

I had this question because infrared is commonly thought of as heat by laypeople and wanted to know if that was a feature across all radiation or just longer wavelengths.

submitted by /u/Abramsathkay
[link] [comments]

When you inhale dust/ dirt/ pollution, does it stay in your lungs? And if so, does your lung clean itself?

Posted: 05 Jun 2020 07:34 PM PDT