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Saturday, May 30, 2020

How big is the magnetic North (and South) pole? Is it a single point, or does it have an area?

How big is the magnetic North (and South) pole? Is it a single point, or does it have an area?


How big is the magnetic North (and South) pole? Is it a single point, or does it have an area?

Posted: 29 May 2020 03:19 PM PDT

What is the diameter of a lightning? They are always seen like some cm of diameter, but can it be just a diameter at the scale of atoms? Does they get bigger if they have more energy?

Posted: 30 May 2020 05:39 AM PDT

How do materials without free electrons reflect light/images?

Posted: 30 May 2020 05:40 AM PDT

Metallic mirrors reflect light because the free electrons are able to vibrate freely. For objects like shiny plastic with no free electrons how can I see a specular reflection? Can the electrons within the bonds vibrate a bit without being excited? What's the mechanism within non-polar and non-metallic molecules that allows them to produce specular reflection?

submitted by /u/thejeran
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In videos of nuclear tests, what is the first wave that sort of shakes the dust off of everything a few seconds before the actual shockwave hits and destroys everything?

Posted: 30 May 2020 06:27 AM PDT

What is the step above single-cell? Are there any 2-cell organisms? Any 5-cell organisms? 10-cell?

Posted: 30 May 2020 06:57 AM PDT

Why is SARS-CoV-2 infection of T-lymphocytes abortive / not capable of viral replication?

Posted: 30 May 2020 05:32 AM PDT

https://www.nature.com/articles/s41423-020-0424-9

"Similar to MERS-CoV, SARS-CoV-2 infection of T cells is abortive."

SARS-CoV-2 can enter T-cells and release its RNA, but it fails to replicate. In other cells, host cell ribosomes will take viral RNA and synthesize proteins from it, beginning the process of viral replication, but for some reason(s) this does not appear to happen in infected T-cells.

Why is this?

submitted by /u/rabidsoggymoose
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How does Autofocus/Automatic Exposure in a camera work?

Posted: 29 May 2020 08:33 PM PDT

How far along are we when it comes to proving whether or not immunity occurs after having COVID-19?

Posted: 30 May 2020 12:01 AM PDT

How can a misting spray neutralize odour from a sewage treatment plant?

Posted: 29 May 2020 09:20 PM PDT

I saw this video on youtube while looking up fogging machines: https://youtu.be/Kl6vtgIl-nQ

It appears to be a misting spray system, but it is being used at a sewage treatment plant. Is it just water or would they need to use a chemical? What kind of chemical neutralizes sewage odours? Is it a chemical reaction?

submitted by /u/Wraithwain
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So far are there reliably detectable physical differences in the brain structures of individuals diagnosed as psychopathic/sociopathic that help us better understand how to support such individuals? Are there potentially observable indicators that shed light here in any way?

Posted: 29 May 2020 06:13 PM PDT

Just wondering the extent to which we scientifically understand the connection between brain layout nuances that may contribute to the manifesting behaviors that contribute to such labels (assigned scientifically or otherwise) and what the implications are for supporting these individuals to be functioning healthy crime free adults as much as possible.

Thanks!

submitted by /u/willysfat
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Earth flipping. Slowly or not?

Posted: 30 May 2020 03:36 AM PDT

Why do jet streams only occur at high altitudes?

Posted: 29 May 2020 06:44 PM PDT

Additionally, do jet streams remain constant or do they 'die out' like gusts of wind?

submitted by /u/Akatamah
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What is a field? And what are force carriers?

Posted: 29 May 2020 09:15 AM PDT

What is the technical definition of a "field" in physics? It seems like it's just a mathematical description of potential in space, but how do things in a field interact with each other, e.g. in a magnetic field?

Do fields require the presence of force carriers? When a charged particle moves through an electromagnetic field and is deflected, does that mean there was a photon involved in the interaction?

submitted by /u/smeezy
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How is it determined if drugs are "non-habit forming"?

Posted: 29 May 2020 06:16 AM PDT

For example, I just heard a commercial for a sleep aid for children that uses melatonin to help children fall asleep. I understand that this is a naturally produced chemical within the body, but does introducing it into the system cause the body to reduce its production?

submitted by /u/floodster77
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Why Carbon Dioxide is an inorganic substance?

Posted: 29 May 2020 08:48 AM PDT

Friday, May 29, 2020

What happens when photons collide?

What happens when photons collide?


What happens when photons collide?

Posted: 28 May 2020 04:35 PM PDT

I know photons act like a wave and they go at the exact same speed as each other. What if they had a perfectly straight collision trajectory and slammed into each other? Would they recede like normal waves?

submitted by /u/Phalanx9G
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What makes Venus is the most shiniest planet of the solar system?

Posted: 29 May 2020 03:09 AM PDT

Is it the chemical composition of Venus atmosphere or its weather phenomena what generates the shiny optics phenomena? What is the physics process of this phenomenon?

submitted by /u/sgrnetworking
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Are 10G at a centrifuge for 10h the same as 100G for 1h? (in terms of separation etc)

Posted: 29 May 2020 05:37 AM PDT

Meteorologists: Why or how is "tornado alley" shifting east?

Posted: 28 May 2020 09:21 AM PDT

I'm sorry about the flair I was hoping for a meteorology tag.

submitted by /u/clam-clan
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Can evolution explain how complicated defense mechanisms in human body were developed?

Posted: 29 May 2020 05:47 AM PDT

How does evolution explain complicated defense mechanisms such as adaptive immunity in human body? Can mutations alone develop such complicated processes? Have we slowed down the evolution process with technology?

submitted by /u/pahan22
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If the mass and size of the universe are plugged into the schwartzchild radius, it’s a black hole. Why is this brushed off as a coincidence?

Posted: 28 May 2020 09:52 PM PDT

Is the R-Value social or scientific?

Posted: 29 May 2020 03:57 AM PDT

I'm not sure if this makes sense but basically I was wondering whether the r-value for covid was altered by our actions as people (eg by social distancing and self isolating) or whether it was some scientific about the virus itself. If the latter, I then would ask how it can change because surely the contagiousness of the virus wouldn't change?

submitted by /u/DilatedPupils139
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What level of certainty is there regarding the arrangement of continents 10s-100s of millions of years in the future?

Posted: 29 May 2020 02:38 AM PDT

Earlier today I saw a map that showed current geopolitical boundaries, but over continents 50 million years in the future, and although interesting I was curious if that level of specificity was actually defensible. I understand movement speed and directionality of plates are derived from seafloor spreading rates and probably satellite telemetry to some extent (?), but it seems like with so many plates subject to static forces and compositional differences in crust (?) there may be some significant stochasticity at play the further in the future we project (as with many things, but neither here nor there). On the other hand we might be quite confident in what the ebb and flow of future super-continents and subsequent fracturing will look like, just not sure. Sophisticated simulations are probably invoked these days. Thanks!

submitted by /u/Truth_Universal
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What colors DO dogs see? Is it more fun for them to have toys of that color?

Posted: 28 May 2020 03:58 PM PDT

Why are we able to get photos of distant galaxies with the Hubble space telescope that are more clear/focused than the photos of Pluto from it?

Posted: 28 May 2020 02:37 PM PDT

Why do wooden matches in water stick together ?

Posted: 28 May 2020 04:18 PM PDT

If you submerge two matches in water and then put them in a bowl of water so that they are touching on some point, they start moving towards each other and end up parallel. What´s happening there ? Does it have to do with the suface tension of the water or with the wood ?

submitted by /u/Duzae1
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Do women have pain receptors that are homologous to testicle pain receptors?

Posted: 28 May 2020 03:28 PM PDT

Basically, do women have some hypothetical potential to experience the pain of "having someone step on your balls"?

Or are those homologous receptors repurposed in women to perceive something completely different?

submitted by /u/DeshawnAnjani277
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Why is SARS-COV both severe and acute?

Posted: 28 May 2020 01:30 PM PDT

I thought severe and acute are synonyms and either one could have been used to describe the disease but not both.

Are there certain criteria or scientific definitions that warranted the use of both words?

A bit of a random question I have stuck in my head... any response is appreciated!

submitted by /u/LarsQuell
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Do antibody studies of covid-19 provide a valid death rate estimate worth comparing to the flu?

Posted: 28 May 2020 09:46 AM PDT

I heard on NPR a recent study indicated that the death rate of covid, according to antibody studies, indicates the death rate of infection is closer to .6%. The reported then compared that number to the often cited .1% death rate for seasonal flu. Is that a valid comparison? Are serological studies done on seasonal flu? Do such studies provide a reasonable estimate for time frame of infection that would be needed to make a death rate estimate?

submitted by /u/itprobablynothingbut
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Is there a reliable scientific/medical journal study that studied effectiveness of masks during COVID?

Posted: 28 May 2020 10:14 AM PDT

I am under the impression that it's helpful to wear a mask and even more so that it doesn't hurt to wear a mask, but I would be interested in reading a non-government source that has conducted a quality study on it. I haven't found anything that seemed overtly qualified from my Google searches, but I am not necessarily adept at finding such things.

submitted by /u/jonathan4211
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Thursday, May 28, 2020

If you transplanted a multi-decade old tree from a place like say Florida to up north, would the tree “know” to lose it’s leaves in the fall or would it just die?

If you transplanted a multi-decade old tree from a place like say Florida to up north, would the tree “know” to lose it’s leaves in the fall or would it just die?


If you transplanted a multi-decade old tree from a place like say Florida to up north, would the tree “know” to lose it’s leaves in the fall or would it just die?

Posted: 27 May 2020 09:46 PM PDT

What was the peak population of dinosaurs?

Posted: 27 May 2020 05:22 PM PDT

ELI8 for Rain vs Bubbles please?

Posted: 28 May 2020 07:02 AM PDT

My 8yo recently discovered that bubbles do not pop in the rain, even rain brought in by a tropical storm (honestly, I was surprised too, I thought the torrential downpour would pop them). I tried to look up the science behind it and couldn't find an explanation that I understood well enough to explain it on the 8yo's level.

Can any one help us out? We're still curious and ridiculously gleeful that you can blow bubbles in a tropical storm and they will just happily beebop around in the wind and rain. TIA!

submitted by /u/vixenspixie
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Could we launch a space shuttle using a railgun?

Posted: 28 May 2020 01:06 AM PDT

Could we make an electric SSTO using a railgun and ion engines? although we haven't reached escape velocity with a railgun, could we still do it if we just use enough energy? happy to answer any questions

submitted by /u/SaintPanda_
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Why are rocket launch windows so narrow/sparse?

Posted: 27 May 2020 01:40 PM PDT

The falcon 9 launch today was scrubbed due to weather, the commentators seemed to think the weather would have cleared 10 mins after T-0, I get that they need to arrive on time to intercept ISS at the right moment, but why not just wait 90 mins for ISS to come back around?

submitted by /u/REmarkABL
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Do we have any idea what came before our solar system?

Posted: 28 May 2020 01:59 AM PDT

My understanding is that around 4.5 billion years ago our star formed out of a cloud of gas and dust, and that our planet formed out of what was left. But what was that gas and dust? Where did it come from? I am assuming that it did not come directly from the Big Bang, because there was too much complex stuff in there. So did we form from the remenents of a supernova or a single dead old star? Did we form out of many old stars or did many new stars form out of a single old star? If the old stars had run out of fuel and finally died, where did the new fuel come from to ignite new stars?

submitted by /u/DangerousJefe
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Why is prostate cancer associated with bone loss?

Posted: 28 May 2020 07:04 AM PDT

Prostate cancer likes to eat your bones - is it because of metastasis, is it treatment-induced and what is the mechanism?

submitted by /u/ColdWindBlowsss
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Is there a relationship between bullet density/weight and speed needed in order to penetrate a body?

Posted: 28 May 2020 03:06 AM PDT

Assuming you were able to shoot something other than a bullet, like earplugs made of foam/gym, or a vitamin pill, or a rubber eraser without it breaking up, how would you calculate the speed needed for it to "kill" a human, or simply put penetrate his body?

I remember someone telling me if you drop a dollar from the Empire State Building you could kill someone due to the speed it reaches falling down, but I assume that's also because it keeps accelerating while a bullet doesn't? (Correct me if I'm wrong)

submitted by /u/MrMarchMellow
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Material scientists, what specifically is going on in an OEM automotive brake rotor that allows it to withstand/dissipate heat more effectively than aftermarket rotors?

Posted: 28 May 2020 06:25 AM PDT

I've done my fair share of brake jobs and I've always wondered how OEM rotors are able to take far more abuse than their aftermarket counterparts.

submitted by /u/xeonisius
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Etymologists: How exactly do etymologists determine, with certainty, that in some form a word transferred from one unrelated language to another, at some point in the past?

Posted: 27 May 2020 05:25 PM PDT

I know that documents/primary sources are an essential resource in regards to etymology - but my studies only required a few linguistics courses. So my knowledge on etymology itself is lacking.

How exactly do etymologists determine when a word transferred from one language, to another language that does not share a common ancestry? For example, words in modern Japanese that came from the English language, or another indo-european language. I am sure there are countless examples with many languages - but most importantly, what sort of things are taken as solid proof of the transfer occurring?

Is there much debate among etymologists about how those words got their origins? Also, are there examples of words that came to be, similar to the concept of convergent evolution?

Edit: added a word for clarity.

submitted by /u/SmallRedBird
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Why do planets like Neptune and Uranus have rocky cores the size of Earth and yet insanely huge atmospheres, and yet the Earth has such a thin atmosphere?

Posted: 27 May 2020 05:25 PM PDT

Side question - Is the Earth the "rocky core" of our planet?

submitted by /u/_imhigh_
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What would happen to plants and animals if the magnetosphere was weakened?

Posted: 27 May 2020 07:49 PM PDT

I know that exposure to solar radiation, in space for example, can cause blindness or genetic mutations. I'm wondering how an increase in solar radiation would effect flora, fauna, and the climate.

submitted by /u/mannydee42
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What do we know about Covid-19 and mutation rate?

Posted: 27 May 2020 12:20 PM PDT

I haven't seen this asked, but if it was I apologize for missing it. I have several related questions I'm hoping y'all can help with. To my knowledge, viruses can mutate at will. Are there concerns about Covid-19 mutating? Do we know the rate at which that virus is likely to mutate? If the virus mutates, is it possible for it to become more severe/lethal? How would scientists know if it did mutate?

submitted by /u/Kalinyx848
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How long does magnetic reconnection take?

Posted: 27 May 2020 08:33 PM PDT

How long does the sun's plasma take to break apart its field and reconnect them? I've tried searching but to no avail. One article suggests it is a "lengthy process", but doesn't elaborate.

submitted by /u/Cheesebun19_
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Do we know in what order the five senses developed?

Posted: 27 May 2020 06:04 PM PDT

What is the smallest thing an ant can see?

Posted: 27 May 2020 02:36 PM PDT

As most of the cells are impossible to see to human eye, would it be that hard for smaller and smaller animals to see it?

submitted by /u/rThiagoM
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How long do hand sanitizers like Purell continue to kill germs and viruses after application?

Posted: 27 May 2020 08:36 AM PDT

Wednesday, May 27, 2020

AskScience AMA Series: Hello Reddit! We're a group of climate researchers and engineers working on new technologies to remove carbon from the atmosphere. Ask us anything!

AskScience AMA Series: Hello Reddit! We're a group of climate researchers and engineers working on new technologies to remove carbon from the atmosphere. Ask us anything!


AskScience AMA Series: Hello Reddit! We're a group of climate researchers and engineers working on new technologies to remove carbon from the atmosphere. Ask us anything!

Posted: 27 May 2020 04:00 AM PDT

We're Nan Ransohoff and Ryan Orbuch from the Climate team at Stripe. Our work to mitigate the threat of climate change focuses on an underexplored part of the problem-removing carbon from the atmosphere directly, which is essential if the world is to meet its warming targets. Last week, after a rigorous search and review from independent scientific experts, we announced Stripe's first purchases from four negative emissions projects with great potential. We hope this will help create a large and competitive market for carbon removal.

CarbonCure: I'm Rob Niven, Founder and CEO of CarbonCure Technologies. Our technology chemically repurposes waste CO_2 during the concrete manufacturing process by mineralizing it into calcium carbonate (CaCO_3)-reducing greenhouse gas emissions, lowering material costs, and improving concrete quality. The technology is already being used at 200+ concrete plants from Miami to Singapore to build hundreds of construction projects from highrises to airports.

Charm Industrial: We're Kelly Hering and Shaun Meehan, founding engineers at Charm Industrial. We have created a novel process for converting waste biomass into bio-oil, which we then inject deep underground as negative emissions-creating a permanent geologic store for carbon.

Climeworks: I'm Jan Wurzbacher, co-CEO of Climeworks. We use renewable geothermal energy and waste heat to capture CO_2 directly from the air, concentrate it, and permanently sequester it underground in rock formations.

Project Vesta: We're Eric Matzner and Tom Green from Project Vesta. Project Vesta captures CO_2 by using an abundant, naturally occurring mineral called olivine. Ocean waves grind down the olivine, which captures atmospheric CO_2 from within the ocean and stabilizes it as limestone on the seafloor.

Proof!

We'll be answering questions from 10am Pacific / 1pm Eastern (17 UT). Ask us all anything about our work!

Username: StripeClimate

submitted by /u/AskScienceModerator
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If a mother bird couldn't find enough food, would she let all her babies starve, or favor one/some and only feed them?

Posted: 26 May 2020 03:23 PM PDT

Sort of a morbid question, I know. A friend had a nest of robins in their yard, and just found all the babies dead under the nest, and hypothesized that a lack of food could be the cause of death. I didn't think that was likely, but didn't want to bring it up or force the issue when my friend is quite sad about the dead baby birds. I figure that if the mama bird knew that she wasn't finding enough food, she would choose one of her babies to favor and feed with what she could find, to give the best chance of her genes surviving in the next generation. Is this true? Or would she feed them equally and let them all die? If it informs the answer, the mother is still alive. Thanks in advance!

submitted by /u/PeanutCalamity
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Ask Anything Wednesday - Physics, Astronomy, Earth and Planetary Science

Posted: 27 May 2020 08:08 AM PDT

Welcome to our weekly feature, Ask Anything Wednesday - this week we are focusing on Physics, Astronomy, Earth and Planetary Science

Do you have a question within these topics you weren't sure was worth submitting? Is something a bit too speculative for a typical /r/AskScience post? No question is too big or small for AAW. In this thread you can ask any science-related question! Things like: "What would happen if...", "How will the future...", "If all the rules for 'X' were different...", "Why does my...".

Asking Questions:

Please post your question as a top-level response to this, and our team of panellists will be here to answer and discuss your questions.

The other topic areas will appear in future Ask Anything Wednesdays, so if you have other questions not covered by this weeks theme please either hold on to it until those topics come around, or go and post over in our sister subreddit /r/AskScienceDiscussion , where every day is Ask Anything Wednesday! Off-theme questions in this post will be removed to try and keep the thread a manageable size for both our readers and panellists.

Answering Questions:

Please only answer a posted question if you are an expert in the field. The full guidelines for posting responses in AskScience can be found here. In short, this is a moderated subreddit, and responses which do not meet our quality guidelines will be removed. Remember, peer reviewed sources are always appreciated, and anecdotes are absolutely not appropriate. In general if your answer begins with 'I think', or 'I've heard', then it's not suitable for /r/AskScience.

If you would like to become a member of the AskScience panel, please refer to the information provided here.

Past AskAnythingWednesday posts can be found here.

Ask away!

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Have ACE inhibitors been tested as a treatment for COVID-19?

Posted: 27 May 2020 06:11 AM PDT

I am most likely massively over simplifying this, but if the SARS-CoV-2 virus enters host cells using angiotensin-converting enzyme, why can't the virus be stopped/slowed down from entering cells using angiotensin-converting enzyme inhibitors?

submitted by /u/qwakery
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Can you build a laser powerful enough to mess with satellites in orbit?

Posted: 27 May 2020 06:32 AM PDT

A conversation about Starlink got me started down a rabbit hole of imaging satellites currently in orbit and potential "vandalism" from the ground. I'm wondering if imaging satellites could be tracked and blinded by ground-based laser for significant portions of their orbit, and if so why this isn't a common occurrence.

submitted by /u/Dux0r
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If the coronavirus is respiratory and you can't get it from eating infected food, why can you get it through your eyes?

Posted: 26 May 2020 12:39 PM PDT

I have read articles stating that there is no evidence of anyone getting COVID-19 via food. The reasoning I have seen medical experts give is that COVID-19 and its virus are respiratory, so you get it from breathing it in, and if you eat it, your digestive system is separate so you won't get infected. But why then would getting the virus on your hands and then touching your eyes infect you? With your nose and mouth, my assumption was that you could end up breathing it in somehow. But I don't understand why it getting in your eyes would give it to you. I haven't seen this specifically explained anywhere. Thank you!

submitted by /u/llamastinkeye
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Is COVID-19 receiving ADE from other coronaviruses?

Posted: 27 May 2020 12:05 AM PDT

Do our bodies make antibodies with multiple paratope configurations for the same pathogen?

Posted: 26 May 2020 12:37 PM PDT

The SARS-COV-2 virus has many different unique epitopes. When a person gets infected, does their body actually make antibodies with multiple different paratopes?

In other words, does a body's antibody response actually consist of various antibodies with various differing paratopes binding to various different unique epitopes on a single pathogen?

A single SARS-CoV-2 virus could be surrounded by antibodies, but they're actually binding at different epitope areas based on their various different paratope configurations, with some having a higher binding affinity than others?

submitted by /u/rabidsoggymoose
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Could previous exposure to other human coronaviruses prevent COVID-19 infection?

Posted: 26 May 2020 09:01 AM PDT

I was reading this article T cells found in COVID-19 patients 'bode well' for long-term immunity which says

The teams also asked whether people who haven't been infected with SARS-CoV-2 also produce cells that combat it. Thiel and colleagues analyzed blood from 68 uninfected people and found that 34% hosted helper T cells that recognized SARS-CoV-2. The La Jolla team detected this crossreactivity in about half of stored blood samples collected between 2015 and 2018, well before the current pandemic began. The researchers think these cells were likely triggered by past infection with one of the four human coronaviruses that cause colds; proteins in these viruses resemble those of SARS-CoV-2.

Regarding previous exposure to human coronaviruses, NL63 looks awfully similar to COVID-19 because they both attack via the ACE2 receptor. What kind of research would be needed to establish a link between NL63 exposure and COVID-19 immunity? If there is a link between NL63 (or another human coronaviruses) exposure and COVID-19 immunity, would intentionally exposing people to NL63 act like a natural vaccine to COVID-19?

submitted by /u/fasteddie31003
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Can ants smell their food, and if so, from how far away?

Posted: 26 May 2020 06:24 PM PDT

Do they find food through a sense of smell or some other sense, or is it just random luck? Just curious if the ants are actively "hunting" their food supply.

submitted by /u/schelant15
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Do volcanic eruptions affect Earth's magnetic field?

Posted: 26 May 2020 01:39 PM PDT

I'm doing a little research about volcanoes and I want to know the connection between volcanoes and magnetics. I learned that the Earth's magnetic field is basically generated by the flowing iron-rich magma and the rotation of the Earth (which creates a dynamo effect). If my understanding of the magnetic field is off pls correct me. Does this mean volcanic eruptions somehow affect the magnetic field because of the magnetic lava? Do volcanoes have anything to do with the polarity switches throughout Earth's history? What's the connection between volcanoes and the magnetic field?

submitted by /u/floppycheeseandchoc
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Is all crude oil pumped from any given well the same?

Posted: 26 May 2020 01:27 PM PDT

What I mean by this is, do they have the same proportion of hydrocarbons for example? I understand that cracking separates the hydrocarbons from crude oil by different molecular weights through fractional distillation, so I was wondering if the average barrel of oil from one well might have a different proportion of some hydrocarbon than from another well.

If so, does this mean that oil from some wells, given the difference in these proportions, might be more or less valuable than the oil from another well?

Thanks.

submitted by /u/Dark_T100
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What was the first domesticated animal?

Posted: 26 May 2020 08:24 AM PDT

And does it differ area from area; did the humans in Mesopotamia domesticate one animal and those living in South America some other first?

submitted by /u/dsdrft
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How is a decaf coffee made? What is the process of decafing a caffeine drink? Thanks.

Posted: 26 May 2020 12:33 AM PDT

What makes the seeds in a chilli spicier than the flesh?

Posted: 26 May 2020 01:14 AM PDT

Does the information passed through separated twisted pair photons, such as in quantum radar, travel faster than the speed of light?

Posted: 26 May 2020 11:43 AM PDT

I've been loosely following the subject, it is a game changer. It was my understanding that when twisted photons are separated and one undergoes a state change, then the other registers the same state change regardless of the distance between the two. Is this instantaneous? If it is instantaneous, would not the information of the state change have, in effect, traveled faster than the speed of light? Here is a small reference article: https://www.technologyreview.com/2019/08/23/75512/quantum-radar-has-been-demonstrated-for-the-first-time/

submitted by /u/urkldajrkl
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Why does somatotropin (HGH) released from the pituitary gland cause bodily growth but not artificial HGH?

Posted: 26 May 2020 08:16 AM PDT

In other words, why does an overactive pituitary gland, such as in gigantism/acromegaly, cause physical growth, but not when artificially introduced? I ask because I was reading about Robert Wadlow, and it's said he probably had a tumor on his pituitary that caused the excessive growth. Obviously his height wasn't the result of his genes, as his parents were normal height. So, if a malfunctioning pituitary can cause excessive growth, why doesn't artificial HGH? If a child had idiopathic short stature (ISS) due to genetics, why would HGH therapy not cause extra growth in the same way a tumor would?

Sorry if my question is worded strangely. Thanks!

submitted by /u/DrBeePhD
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