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Sunday, June 16, 2019

What causes the surge in luteinizing hormone just prior to ovulation?

What causes the surge in luteinizing hormone just prior to ovulation?


What causes the surge in luteinizing hormone just prior to ovulation?

Posted: 16 Jun 2019 12:12 AM PDT

I have read a few physiology textbooks that were published a few years ago, and I have not gotten anything concrete.

I read from the 9th edition (latest) of Sherwood Physiology, which states that there are two sets of kiss1 neurons in the hypothalamus. According to the text, negative feedback involves low concentrations of estrogen inhibiting the kiss1 neurons in the arcuate nucleus whereas positive feedback involves high concentrations of estrogen stimulating the kiss1 neurons in the anteroventral periventricular nucleus. Kiss1 neurons secrete kisspeptin, which act on GnRH-secreting cells in the hypothalamus.

However, the 13th edition (latest) of Guyton-Hall says that "the cause of this abrupt surge in LH secretion is not known". It states two possible explanations. The first one is the one that Sherwood gives - about how estrogen has a "peculiar positive feedback effect" of stimulating pituitary secretion of LH, which is in "sharp contrast to the normal negative feedback effect of estrogen that occurs during the remainder of the female monthly cycle." The second explanation Guyton-Hall suggests is that the granulosa cells begin to secrete a small but increasing amounts of progesterone a day or so before the LH surge, and it has been suggested that this secretion might be the factor that stimulates the excess Lh secretion.

My main question is: since the publication of these textbooks, have we learnt anything new or is this still something that we are not sure of?
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edit1: Added some info for clarification.

submitted by /u/COX-1
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Is there actually a solution to the twin paradox?

Posted: 16 Jun 2019 06:50 AM PDT

All the ones I've come across assume that the twin on the rocket is the one changing velocity, (accelerating) which breaks the symmetry, causing him to come back younger. The whole point of relativity is that there are no preferred frames of motion. (each twin would have the same right to claim that it's the other one who is accelerating) In general relativity it's not only the apple that falls to the earth, but the earth that falls to the apple. Both points of view are equally valid. To have it simplified, substitute the twins with two objects in empty space that break apart and come back together again. There is nothing else in that universe for these objects to move relative to so what's to decide if one object's acceleration was any more real than the other?

submitted by /u/Doctorrsponge
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How do bees know their way back home?

Posted: 15 Jun 2019 09:41 PM PDT

I was watching my garden this morning and I saw some bees buzzing around. I followed some of them and found out that they visit many flowers in a way that appears very random. How can they know their way back home?

submitted by /u/greenishbamboo
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On the complex number plane, why are coordinates expressed as a value, like 2i+1, and not as an ordered pair, like (1, 2i)? Or do they represent something other than corrdinates?

Posted: 15 Jun 2019 07:18 PM PDT

Are birds monophyletic?

Posted: 16 Jun 2019 07:43 AM PDT

Obviously at some point all birds share a common ancestor, but I'm wondering if that family tree also contains dinosaurs that we do not consider to be birds. Essentially, is the only truly defining trait of the "avian dinosaurs" that they were the ones that survived to the present, or are they are clearly distinct taxonomic group?

submitted by /u/Unearthed_Arsecano
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What makes mining asteroids so potentially profitable?

Posted: 15 Jun 2019 07:12 PM PDT

To add to the question, what rocks/ore/minerals within the asteroid are so valuable and who on earth (literally!) would pay big bucks for it?

submitted by /u/Chainsaw_Hamster
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Did insects evolve from crustaceans?

Posted: 15 Jun 2019 08:47 AM PDT

Why was carbon-dioxide used in the Chicago Pile 1?

Posted: 15 Jun 2019 09:35 PM PDT

I read that the Chicago Pile 1 was encased by a large balloon which was then filled with carbon-dioxide. What would this accomplish?

submitted by /u/Decidedyeti
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When elements and/or compounds freeze, do the molecules arrange themselves in a hexagonal array, or is only H20 only like that? If elements and/or compounds do not form hexagonal arrays when frozen, what kind of structure do they form?

Posted: 15 Jun 2019 05:16 PM PDT

Has a CPU ever been designed for a specific programming language ?

Posted: 15 Jun 2019 03:25 PM PDT

Not assembly of course

submitted by /u/pheqh
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What makes sunset red?

Posted: 15 Jun 2019 06:42 PM PDT

Sometimes sunsets tend to more more red-ish. From where I live, most of the time it is not. The sky is dark blue. On the other hand, on other times, a big chunk of the sky would be red. Why is that?

submitted by /u/Akdi_1
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Does background radiation play any role in genetic mutation, ageing, or development of cancer?

Posted: 15 Jun 2019 03:23 PM PDT

How are we able to predict trajectories based only on feeling?

Posted: 15 Jun 2019 05:25 AM PDT

How are we able to "calculate"without actively using any calculations?

submitted by /u/Neyrolint
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So we know that black holes exist, does that mean the theoretical white hole exists also?

Posted: 15 Jun 2019 07:52 PM PDT

If a computer is based on transistors that go off and on for a 0 or 1 how do computers do basic math functions(add,subtract,multiply,divide)?

Posted: 15 Jun 2019 02:50 PM PDT

Sorry I'm on mobile but read title

submitted by /u/innocent-9-year-old
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Do cars in higher elevations get better gas mileage?

Posted: 15 Jun 2019 05:25 AM PDT

I'd think so, because there's less air to create drag, but then again, maybe less/thinner air affects the engine somehow.

submitted by /u/ChaseDerringer
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Why doesn't the well ordering principle apply to nonnegative rationals, or negative integers?

Posted: 15 Jun 2019 08:08 AM PDT

The well ordering principle is that every nonempty set of nonnegative integers has a least element.

For a set of nonnegative rationals, shouldn't the least element be zero, or whatever number is closest to zero?

For a set of negative integers, shouldn't the least element be the negative number with the largest magnitude? Why can't the well ordering principle apply to these sets?

submitted by /u/AmazingMeltedSnowman
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Saturday, June 15, 2019

Why can hormone therapy make a clitoris grow but can't make a penis grow?

Why can hormone therapy make a clitoris grow but can't make a penis grow?


Why can hormone therapy make a clitoris grow but can't make a penis grow?

Posted: 15 Jun 2019 03:53 AM PDT

Were CO2 levels ever higher than they are at the moment?

Posted: 15 Jun 2019 04:46 AM PDT

I get that climate change is due to the drastic change in Greenhouse gasses, and that nature & humans won't be able to adapt as fast, but since petroleum is "dead dinosaurs", at the time of dinosaurs, were CO2 levels higher than they are now?

submitted by /u/Salameh89
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How do we know how much energy the sun produces?

Posted: 14 Jun 2019 09:53 PM PDT

What are the differences between Chernobyl, the Tsar Bomba and a modern day nuclear weapon / device in terms of radioactivity?

Posted: 15 Jun 2019 03:26 AM PDT

I'm curious about which would be the most dangerous post explosion. I just finished watching the Netflix show Chernobyl but I'm curious if it was hyped up a little for Hollywood or if its completely realistic, and how it compares to other nuclear events?

Thanks in advanced!

submitted by /u/ntb899
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Does the increase in education costs lead to a lower level of education at a given generation level?

Posted: 15 Jun 2019 07:31 AM PDT

And more important: are they studies that point a significative impact on the competitivity of a country over a long period of time (at least 10 years)? The question focus especially US where the cost of education skyrocketed the last 25 years but may be other countries experienced similar phenomenon.

submitted by /u/EmuVerges
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Why do bad smells actually smell bad to us?

Posted: 15 Jun 2019 07:10 AM PDT

What Y-chromosome haplogroup did hunter-gatherer Europeans and neolithic Anatolian farmer migrants to Europe belong to?

Posted: 15 Jun 2019 07:03 AM PDT

Can someone explain the reaction that makes retrobrite work?

Posted: 15 Jun 2019 03:09 AM PDT

Retrobrite is fixing the color on old plastic by soaking it in hydrogen peroxide while it's out in the sun.

https://www.youtube.com/watch?v=qZYbchvSUDY

I'm just curious how this works?

submitted by /u/Someguy2020
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What is the difference between an organism made up of smaller individuals(e.g. sea salp, pyrosome) vs. a multicellular organism?

Posted: 14 Jun 2019 08:20 PM PDT

How does Hela Cells work ? And why are they immortal ?

Posted: 15 Jun 2019 12:35 AM PDT

Is driving on a regular basis beneficial for our brains and help reduce the risk of brain disorders in old age?

Posted: 14 Jun 2019 07:42 PM PDT

What causes degradation of lithium battery life after repeated charge cycles? What practices optimise battery life and what are the reasons behind these?

Posted: 14 Jun 2019 11:56 PM PDT

We all know battery life decreases with use, why is this for lithium batteries?

Some common recommendations to lengthen the life of batteries I have come across:

-Charge only to 80%

-Do not leave charging for long periods of time

-Store at 50% charge if not using for long periods

What are the reasons for these? Are there any others?

submitted by /u/cabbage_in_tree
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What enzyme converts glycerol to glucose 6 phosphate?

Posted: 15 Jun 2019 12:20 AM PDT

Do heavy elements like uranium sink to the center of the earth?

Posted: 14 Jun 2019 05:33 PM PDT

Do heavy elements, like uranium sink to the center of the earth or does the convection of the liquid layer keep it mixed? Other forces I haven't thought of?

Geologists of redit: I eagerly await your answer.

submitted by /u/nedeta
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For Glacial periods and Milankovitch Cycles, does Low or High eccentricity favor colder climates?

Posted: 14 Jun 2019 08:59 PM PDT

As far as I'm concerned, the Semi-Major axis does not change as eccentricity changes. Therefore, a less eccentric orbit would result in a further average distance from the sun, leading to less insolation and colder climates.

However, I've also heard things about disproportionate season length (Kepler's 2nd Law), and stuff about the Aphelion and Perihelion being different, making highly eccentric orbits more favorable for glaciation.

So far, the internet doesn't have a rock-solid answer, and I would like to know.

submitted by /u/HugoTroop
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Is the dwarf planet Haumea within our solar system?

Posted: 14 Jun 2019 08:10 PM PDT

what does it orbit? it has moons?

submitted by /u/goombah111
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Friday, June 14, 2019

AskScience AMA Series: We're Sarah Stellwagen (UMBC) and Rebecca Renberg (ARL), authors of a G3: Genes, Genomes, Genetics article on sequencing spider glue genes. They're massive - the largest has a coding sequence over 42,000 bases long, and could lead to exciting advances in biomaterials. AUA!

AskScience AMA Series: We're Sarah Stellwagen (UMBC) and Rebecca Renberg (ARL), authors of a G3: Genes, Genomes, Genetics article on sequencing spider glue genes. They're massive - the largest has a coding sequence over 42,000 bases long, and could lead to exciting advances in biomaterials. AUA!


AskScience AMA Series: We're Sarah Stellwagen (UMBC) and Rebecca Renberg (ARL), authors of a G3: Genes, Genomes, Genetics article on sequencing spider glue genes. They're massive - the largest has a coding sequence over 42,000 bases long, and could lead to exciting advances in biomaterials. AUA!

Posted: 14 Jun 2019 04:00 AM PDT

Hello, Reddit. We are Sarah Stellwagen, a biology postdoc at UMBC, and Rebecca Renberg, a research scientist at the United States Army Research Laboratory. We're excited to share how we figured out how to sequence two incredibly challenging spider glue genes for the first time, and the possibilities this opens up for science.

Spider glue is a modified version of spider silk that keeps a spider's prey stuck in its web. Unlike silk, it's a liquid both inside and outside of the spider. Because of this, spider glue might be easier to produce in the lab than silk, which could lead to major advances in biomaterials. There are so many potential applications to explore in the future, such as using it to protect crops from pests instead of using insecticides.

We'll be here to answer your questions at 11:30 a.m. EDT / 8:30 a.m. PDT

Learn more about this work at umbc.edu/go/spider-glue Read the study at https://www.g3journal.org/content/9/6/1909

submitted by /u/AskScienceModerator
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SSRIs and psychedelic empathogens (shrooms, MDMA) both increase serotonin levels in the brain. Why do empathogens cause feelings of interconnectedness and empathy when SSRIs often cause emotional blunting?

Posted: 14 Jun 2019 06:45 AM PDT

Does anticoagulant have any effect on existing blood clots in the body?

Posted: 14 Jun 2019 07:02 AM PDT

So I was watching a video that showed a blood clot trying to get through a heart valve and I got to thinking that my diet isn't the best so I could possibly have one/some trying to form. Anyways I donate plasma so and during the procces my blood is mixed with anticoagulant (sodium citrate) and spun out to remove the plasma before being returned, so my question is: does the anticoagulant have any effect on clots that have already started forming in the body or does it only stop the coagulation process from starting? I only ask because I'm wondering if there is some sort of benifit to my body from having anticoagulant in my veins.

submitted by /u/tictac774
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How does radiation (radioactive) affect electronics?

Posted: 14 Jun 2019 07:09 AM PDT

Why don’t clouds get blown apart?

Posted: 14 Jun 2019 06:07 AM PDT

How do clouds stay together in (mostly) the same shapes in high winds? Why doesn't the wind just disperse the clouds like a cloud of smoke?

submitted by /u/jasonmulle
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What is the difference between XVID vs H264?

Posted: 14 Jun 2019 05:40 AM PDT

I just got told that I should encode my recorded videos with h264. I have always been using xvid until now with no problems.

I use VirtualDub to encode my videos.

I encoded a 1.72GB video with both codecs on the highest quality that VirtualDub would allow.

H264 gave me a 1.1GB file

XVID gave me a 710MB file

I can't really tell the difference in quality.

What makes h264 better than xvid, if anything? And what is the main difference between the two?

submitted by /u/sf8080
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Did fungi ever engage in Endosymbiosis?

Posted: 13 Jun 2019 11:37 PM PDT

A random question that came to my mind yesterday:

As far as I know both plant and animal cells developed due to endosymbiosis, does this also apply to the cells of fungi?
If yes than what exactly happened, they can't have chloroplasts inside their cells because they are not engaging in photosynthesis but are there mitochondria inside them or something completely different but similar in function?

submitted by /u/Correct_My_Spelling
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Does the musicyou listen to when you are young affect what you listen to when you are older?

Posted: 14 Jun 2019 05:25 AM PDT

More specifically, if you listen and enjoy a certain song or genre when you are young does this influence the music you like later? Like if you grew up only listening to heavy metal, would you be more pre-dispositioned to like all metal, or even to not like it?

Or are there too many variables and possibility of random chance to have real evidence?

submitted by /u/ZavrosHellstrand
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Can the creation of monozygotic twins be artificially induced in mammals?

Posted: 14 Jun 2019 04:56 AM PDT

Asking because twin studies are very useful, so inducing this at will would probably be very helpful. Can a fertilized oocyte (a totipotent stemcell) be manipulated to create an exact copy of itself? Or is it purely coincidental?

submitted by /u/ColonConoisseur
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How does the brain isolate a sound when we focus on it?

Posted: 14 Jun 2019 04:25 AM PDT

Say you were sitting in the car listening to music and someone is talking to you. We can choose to focus on the music the person or say the engine of the car, but how does the brain isolate the sound we want to hear rather than it just all seeming like one big noise?

submitted by /u/Joe_Subbiani
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What's the fundamental difference between solids, liquids and gas?

Posted: 14 Jun 2019 03:01 AM PDT

To be more precise, what makes the molecules in a liquid pack densely and stay in a container, in contrast to gas molecules which just "float around"?

submitted by /u/_the_cereal_killer_
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How is dating of excavated site cross-referenced?

Posted: 14 Jun 2019 02:59 AM PDT

I am looking to find materials that specifically address how multiple dating methods are being used to cross-reference and verify that excavated items indeed have the age we think they do.

Not a denier, looking for ammo to talk to deniers of the young earth creationist type.

submitted by /u/orwell_goes_wild
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What is the theory that the complexity of a system is correlated to the amount of energy flowing through it?

Posted: 13 Jun 2019 01:58 PM PDT

I was listening to a history podcast, and the narrator described a theory that posited that the level of complexity is a system is proportional to the amount of energy flowing through it. In this context, I think he was describing early societies which collapsed after they lost access to resources. But, if I remember correctly, the theory applied to all types of systems, not just social systems. I'm intrigued by the idea, and want to read more about it, but I can't remember who the originator of the theory was, or even which podcast I was listening to.

Who's theory is this? Where can I learn more about it?

BTW, I chose "mathematics" for the flair of this post, but I don't really know what branch of science this theory belongs too.

submitted by /u/quinncom
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Does watching horror movies make you less fearful of “scary” things in real life?

Posted: 14 Jun 2019 01:48 AM PDT

When I toss a tennis racquet, ping pong paddle, or my shoe in the air almost perfectly vertically, it does not just flip. It does a twist as well. Can someone explain this phenomenon?

Posted: 13 Jun 2019 12:21 PM PDT

What's the difference between a low fever and a high fever? Does your body just know to set the thermostat higher for certain illnesses?

Posted: 13 Jun 2019 12:00 PM PDT

How do we get a sense of "current events" in the cosmos?

Posted: 13 Jun 2019 08:39 PM PDT

I just wanna throw this out there... I dont know much about space. Anyways...

Let's just say a satellite takes a photograph of an exoplanet from 10 light years away. That should mean that the image is made up of light that is 10 years old. How do we know that this exoplanet is still there? A meteor could have destroyed it 2 years prior to the photograph being taken and the light from the explosion would still have another 8 years to travel before we saw it. Or do we have a way of knowing for sure that planet is really there, at that moment the photograph is taken?

submitted by /u/Google-me-noodles
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How does carbon capture technology work? Would removing carbon from the atmosphere reverse the effects of climate change or just keep them from getting worse?

Posted: 13 Jun 2019 05:52 AM PDT

Can bleach disinfect ebola?

Posted: 13 Jun 2019 11:44 AM PDT

I was watching Hot Zone on NatGeo recently, and i in it they use bleach to disinfect everything that has been contaminated, is this actually true? And if yes, do they use the same store bought bleach or is it some special powerful ebola killer bleach?

submitted by /u/r_antares
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