AskScience AMA Series: Biomedical research has a diversity problem that NIH scientists & other researchers are working to fix. The All of Us Research Program just released nearly 100K whole genome sequences from a group of diverse participants into our secure Researcher Workbench. Ask us anything! | AskScience Blog

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Monday, March 28, 2022

AskScience AMA Series: Biomedical research has a diversity problem that NIH scientists & other researchers are working to fix. The All of Us Research Program just released nearly 100K whole genome sequences from a group of diverse participants into our secure Researcher Workbench. Ask us anything!

AskScience AMA Series: Biomedical research has a diversity problem that NIH scientists & other researchers are working to fix. The All of Us Research Program just released nearly 100K whole genome sequences from a group of diverse participants into our secure Researcher Workbench. Ask us anything!


AskScience AMA Series: Biomedical research has a diversity problem that NIH scientists & other researchers are working to fix. The All of Us Research Program just released nearly 100K whole genome sequences from a group of diverse participants into our secure Researcher Workbench. Ask us anything!

Posted: 28 Mar 2022 04:00 AM PDT

The National Institutes of Health's All of Us Research Program is inviting one million or more people across the U.S. to help build one of the most diverse health databases in history. In support of our recent controlled tier and genomic dataset announcement, we will be answering questions about genomics, diversity in biomedical research, and how the All of Us Research Program's dataset may help drive medical research forward and improve health equity.

We are:

We'll be here to respond to questions between 1pm - 5pm ET (17-21 UT), ask us anything!

Username: /u/AllofUsNIH

submitted by /u/AskScienceModerator
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How does our brain measure the age of memories?

Posted: 28 Mar 2022 09:10 AM PDT

How can we tell if something happened before something else? How can your brain recall the date of something you saw or learned?

submitted by /u/Walid_Fakhfakh
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Which animals have the largest vocal range?

Posted: 28 Mar 2022 08:04 AM PDT

I did some quick googling but only got stuff for hearing range, which is more easily measurable. The average human has a range between 2 - 3 octaves for full voice, but there are lots of exceptions and this can be expanded with training. What about the rest of the animal kingdom?

Edit: After some discussion below here's my preliminary definition of vocal range: The number of pure tones capable of being produced by the voluntary movement of an internal apparatus similar to the vocal cords in humans.

submitted by /u/VoodooPatches
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Why can’t we see a new moon?

Posted: 28 Mar 2022 01:42 AM PDT

Why don't we see a big round dark circle floating around creating an eclipse of the stars?

submitted by /u/CandyOwn7649
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Do caves / cavern systems exist on Mars? If they do, how deep would we have to go to be in an area that is warm enough to support life?

Posted: 28 Mar 2022 05:31 AM PDT

Why is argon so abundant in Earth’s atmosphere?

Posted: 27 Mar 2022 08:30 AM PDT

Looking at a pie chart of Earth's atmospheric composition, argon gets its own "slice", being nearly 25x more abundant than all other non-oxygen/nitrogen gases COMBINED. Why should this be the case?? I understand that lack of reactivity probably accounts for some of it, but that still doesn't explain why argon is much more abundant than other noble gases, like neon and krypton.

Thanks for any info you can provide!

submitted by /u/opteryx5
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If a mother is malnourished during childhood, will it affect a baby she has later in life?

Posted: 27 Mar 2022 08:47 AM PDT

What really causes diverticulitis?

Posted: 27 Mar 2022 07:50 AM PDT

When an electron and positron annihilate, they give off two gamma rays - is it always exactly two? Might it be more?

Posted: 27 Mar 2022 05:05 AM PDT

And what if a proton and an antiproton annihilate? Will that also usually be two gamma rays?

submitted by /u/SurprisedPotato
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How can pure substances have multiple triple points?

Posted: 28 Mar 2022 04:21 AM PDT

So a triple point is defined as "the temperature and pressure at which three phases (gas, liquid, and solid) of that substance may coexist in thermodynamic equilibrium" but my textbook also says "a pure substance can have a number of triple point, but only one triple point has a solid, liquid and vapor equilibrium.

If it's defined as the point where gas, liquid and solids meet... and there's only one such point... how are there multiple?

My best guess is the "(gas, liquid, and solid)" bit doesn't account for allotropic transformations while my textbook does. Stuff like Ice IV and ice V count as different states so if 3 of those states (where 2 or more could be solid, just different types) converge thats a triple point. Also apparently there's 19 types of water ice so thats just wild. Anyway, is my assumption correct?

submitted by /u/badassito
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How does the body generate heat?

Posted: 27 Mar 2022 09:56 AM PDT

Whenever you get an infection, the body turns up the temperature, which we call a fever right? So how exactly does it generate this excess heat

submitted by /u/Crux_AMVS24
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What exactly is “dry steam”? In the context of rocket engines.

Posted: 28 Mar 2022 12:33 PM PDT

Why is the human body's immune response so ineffective at stopping Bubonic Plague?

Posted: 27 Mar 2022 10:14 AM PDT

The plague ended up causing swelling, necrosis, and explosions in the lymph nodes, the very heart of the adaptive immune system.

Why is the human body so poorly adapted to fight off the plague bacteria? Does the innate immune system just get overwhelmed so quickly the adaptive has no time to kick into gear, or is the plague bacteria unique in some way?

submitted by /u/Alashion
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How can asymptomatic cases cause long-COVID? Doesn't that stem from the damage caused by the initial symptoms?

Posted: 27 Mar 2022 04:40 PM PDT

How do anti leptons and muons interact?

Posted: 28 Mar 2022 03:19 AM PDT

Is there a difference between the way anti leptons and muons interact compared to anti leptons and leptons or anti muons and muons?

submitted by /u/KillerWattage
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How do blood clots go away? Do they dissolve and just eventually move on once small enough or do they just get dislodged randomly?

Posted: 27 Mar 2022 09:44 PM PDT

Why are cancers and tumors so often only detected in their late stages? Why can’t people past a certain age just receive an annual test?

Posted: 27 Mar 2022 08:59 PM PDT

Having just lost a parent to a brain tumor, this question is heavy on my mind. They were around 70, and in and out of the hospital for various ailments. Heart issues, etc. I just find it shocking nobody noticed a brain tumor so advanced the doctors wouldn't even do a biopsy on it, and parent was gone three months after it was detected.

Thanks in advance for any insights.

submitted by /u/Kind-Concept968
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Is there any forms of life that don’t use ADP for storing energy?

Posted: 27 Mar 2022 08:25 PM PDT

Are there any rocks that don't fit neatly into the igneous/metamorphic/sedimentary classification system?

Posted: 27 Mar 2022 07:04 AM PDT

Could increased snowfall mitigate the reduction of the ice caps in regards to reflection of sunlight?

Posted: 27 Mar 2022 09:26 AM PDT

To my understanding increases in snowfall are a consequence of global warming as more water is vaporized. Where I live we've had two record snowy winters in a row, and with things like the Texas blizzard some time ago I started thinking if this increase in snow coverage could somehow mitigate the reduced reflection of sunlight from the melting of the ice caps? Or is it completely negligible?

submitted by /u/Identity_ranger
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Is Ocean Acidification Homogeneous?

Posted: 27 Mar 2022 11:26 AM PDT

Hello,

I've noticed that the pH measurements of oceans are often made at the surface. I think anthropogenic carbon emissions from the oceans also occur at the ocean surface because most of the carbon dioxide we produce is dispersed into the atmosphere.

When I think in the context of heat maps for the pH level of oceans, I intuitively think that the acidification of hot tones will be deeper. Is the acidification in the oceans spreading homogeneously or in the form of an increasing gradient towards the surface?

submitted by /u/BerkayKutsal
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Can you cut a hammerhead worm up into 2-3 pieces and once regrown cut again ad infinitum?

Posted: 28 Mar 2022 02:03 AM PDT

I heard you can only clone plants so many times before the genetics get screwy. What about worms. Would the 30th split be just as viable as the first? Thanks

submitted by /u/deadenddrive555
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Would people who live on different planets age at different rates if one planet moves through space faster than the other?

Posted: 27 Mar 2022 11:17 AM PDT

What is happening physiologically when the urge to sneeze arises?

Posted: 28 Mar 2022 12:45 AM PDT

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