Since the placebo effect is a thing, is the reverse possible too? | AskScience Blog

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Saturday, February 19, 2022

Since the placebo effect is a thing, is the reverse possible too?

Since the placebo effect is a thing, is the reverse possible too?


Since the placebo effect is a thing, is the reverse possible too?

Posted: 19 Feb 2022 04:35 AM PST

Basically, everyone and their brother knows about the placebo effect. I was wondering, is there such a thing as a "reverse placebo effect"; where you suffer more from a disease due to being more afraid of it?

submitted by /u/MadMax2910
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How does drinking water immediately invoke a sense of your thirst being quenched?

Posted: 18 Feb 2022 10:00 AM PST

Since the renin-angiotensin system that triggers the thirst response occurs in the kidneys and would probably take a while to react to increased water, is there some kind of sensor in the stomach or something that lets your body know that water is on the way?

submitted by /u/silverhub89
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(Nuclear Physics) Does the fission of Uranium 235 release all of its binding energy?

Posted: 18 Feb 2022 09:53 PM PST

First off, forgive me if my terminology is off or if I've completely misunderstood something, nuclear physics is still new to me.

So the mass defect of Uranium 235 is ~3.082*10-27kg, which is equivalent to 2.77*10-10 joules, or the binding energy of 7.6 MeV per nucleon. Is all of this energy released when this atom is fissioned into krypton and barium?

On top of this, how energy efficient are modern nuclear plants? (i.e. how much energy is lost in the process instead of turning water into steam?)

submitted by /u/jamx02
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Could a nut and a bolt made of perfectly rigid materials be tightened together?

Posted: 19 Feb 2022 07:42 AM PST

Lets say we have mathematically perfect, rigid material and you make a nut and a bolt out of it - could the two be tightened together?

Im asking because I noticed that good quality nuts and bolts screw into each other with little to no resistance and only become tight once maxed out - what exactly happens at the last bit and why it gets tight? Im assuming the materials get ever so slightly bent, deformed and thats what makes it tight?

submitted by /u/KaktitsM
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Do organ transplants and blood transfusions cause mitochondrial chimerism?

Posted: 19 Feb 2022 07:40 AM PST

Blood and organs contain mitochondria, when they are introduced into a new host, is there a mechanism to prevent their proliferation and interaction with host mitochondria? I can't find research on this topic.

submitted by /u/baconn
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How precisely do we know when the asteroids that caused the end cretaceous extinction hit?

Posted: 19 Feb 2022 05:30 AM PST

Like was it 66.0 MYA, 65.4, 66.8 etc

submitted by /u/MiniHamster5
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Does climate change have an impact on winds?

Posted: 19 Feb 2022 05:19 AM PST

I don't know a lot about winds or what makes up a wind.

I saw recently UK has been having highest ever recorded winds. Which made me wonder, are winds affected by climate change? Are melting ice caps and other destruction of environment affect how fast wind becomes?

submitted by /u/World_Voyager
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Is obesity a cause of or a symptom of poor health?

Posted: 19 Feb 2022 05:47 AM PST

I recently saw a post on r/confidentlyincorrect which has a video of a woman saying that losing weight does not improve a person's health, and that a healthy diet and regular exercise should be the goal instead. In the comments some people are arguing that if you eat better and exercise more that you will lose weight, so that means losing weight must be healthy. This got me wondering: Is obesity in itself a cause of health problems, or is an unhealthy lifestyle the cause of the health problems and obesity is simply another symptom of this lifestyle?

Let's say there is an obese person who is very sedentary and eats a diet consisting entirely of highly processed foods. If this person were to lose weight by reducing the overall amount of food they eat, but eating the same foods and maintaining the same activity level, would this improve their health? Alternatively, if this person were to make no diet or exercise changes at all and were to lose weight by taking diet pills, would this improve their health?

Thanks in advance for your answers!

submitted by /u/SoupFlavoredCockMix
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Are hormones produced once a stimulus triggers their release or are they produced ahead of time and stored somewhere?

Posted: 19 Feb 2022 05:32 AM PST

I looked it up and found a lot of stuff about "secretion". Does that mean the respective glands are pockets that "hold" hormones and then just let them seep out whenever necessary? It would boggle my mind to know that hormones can be produced as quickly as e.g. a rush of fear hits you.

submitted by /u/leapfrog__0
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How efficiently does transfected mRNA produce protein compared to endogenously synthesized mRNA?

Posted: 18 Feb 2022 05:02 PM PST

I've been reading on all the proteins RNAs pick up on their way out of the nucleus, as well as pioneer round translation. I'm wondering how much impact those have on the eventual protein expressivity of the mRNA compared to a more "naked" mRNA that is transfected or injected in.

Of course there all all kinds of tricks with codon optimization, UTR structures, modified nucleosides, etc that can improve translation. But I'm talking about identical mature mRNAs, both capped and tailed identically.

Has anyone ever directly compared how much protein you make from an in vitro transcribed mRNA transcript versus an endogenously transcribed one? No luck finding any papers on the matter.

submitted by /u/thebiotechnologist
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Can a mountain have no rain shadow?

Posted: 18 Feb 2022 05:40 PM PST

So I understand that warm and moist air come up from the sea and make precipitation on one side of a mountain, but what if there's two warm currents on either side?

submitted by /u/Blackened_King
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What do we know about porn effects on chimps or other non-human primates?

Posted: 18 Feb 2022 09:37 PM PST

Do they have favourite style or genre? Does porn causes erectile dysfunction in chimps?

submitted by /u/gjvnq1
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