Beta-blockers help dilate the blood vessels, but yet EP and NE cause vasodilation when they attach to beta-2-adrenergic receptors. Does that mean there are little to no Beta-2 receptors in the peripheral vessels, or does it mean less catecholamines bind to alpha 1 and alpha 2 receptors? | AskScience Blog

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Thursday, January 28, 2016

Beta-blockers help dilate the blood vessels, but yet EP and NE cause vasodilation when they attach to beta-2-adrenergic receptors. Does that mean there are little to no Beta-2 receptors in the peripheral vessels, or does it mean less catecholamines bind to alpha 1 and alpha 2 receptors?

Beta-blockers help dilate the blood vessels, but yet EP and NE cause vasodilation when they attach to beta-2-adrenergic receptors. Does that mean there are little to no Beta-2 receptors in the peripheral vessels, or does it mean less catecholamines bind to alpha 1 and alpha 2 receptors?


Beta-blockers help dilate the blood vessels, but yet EP and NE cause vasodilation when they attach to beta-2-adrenergic receptors. Does that mean there are little to no Beta-2 receptors in the peripheral vessels, or does it mean less catecholamines bind to alpha 1 and alpha 2 receptors?

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I am posting here because I do want an explanation, but I'd like it said in terms any average student would understand, which I don't think ELI5 would be able to provide this time around.

Edit: Thanks to all who have answered my question so far. I'm a nursing student taking Med-Surg (in my second semester out of four to take my NCLEX), which means for now a lot of the material is introductory, but so far I am understanding the material well decently.

submitted by /u/YourFinestPotions
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Does the concept of quantum tunneling translate into chemical reactions?

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Basically, does the idea of a particle tunneling through a barrier have any relation to reaction thermodynamics? For example, two elements react to form a molecule. For the reaction to occur, some amount of energy is required. Is it possible for the reaction to proceed through some "tunneling" mechanism by which the product is produced without making it over the energy barrier? Without the use of a catalyst or something along those lines, could the reactants "tunnel" through the energy barrier and form the product anyway?

submitted by /u/Farts_of_Wisdom
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DIY wind turbine blade aerodynamics. what is the optimal size/angle/material?

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I am using a old izuzu npr alternator for this turbine. I am using a belt system to increase RPMs making the automobile alternator a viable option for wind turbines with hopefully low drag. That being said - I have no clue how large I should make the blades/how thick the blades should be/what I should make said blades out of.

submitted by /u/musclemass220
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Is it possible for planets to orbit two stars, like a figure - eight kinda thing?

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If a perfectly spherical object that is completely uniform in mass has a spherical yet hollow core and another spherical and uniform mass object is placed directly in the center of the first object's cavity would it float?

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Assuming that neither masses are being acted upon by an outside gravity.

submitted by /u/Neilfromkansas
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Could a nuclear reactor operate in space?

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If we had a large space vessel that required vast amounts of electricity, could a nuclear reactor operate in space? It's my understanding nuclear reactors need to dissipate a high level of heat, is this possible in space?

submitted by /u/ezSpankOven
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Can we understand the Planck time and Planck length as the space-time minimal "grid" of the universe ?

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Hello, If the universe is a simulation (i'm not saying it is) or if we want to create a simulation of the universe at the most precise level, could the Planck time and Planck length be used as a grid where every object has a quantified position ?

-> Are the dimensions "analogical" or "numerical". Is there a space time grid ?

Thanks

submitted by /u/PrTesla
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If gravity propagates like light. What is it made of? Something similar to Photon?

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What is the maximum distance that a metal object can reliably be held in place by a magnet?

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Hey everyone, this question was formulated after taking a mechanical engineering control systems class this semester. Though the course is now behind me, the seed of an idea for a side project (inspired by one of our graded projects) has taken root in my head. I've been doing some googling around and tried to crunch some numbers, but I figured it couldn't hurt to ask engineers who have years of experience that have shaped your intuition.

Let's say that I have a hollow, 6" diameter globe with some kind of iron or steel on the inside. Not too heavy, and responsive to magnets. Super similar to stuff like this. If I use off-the-shelf parts and some really fine-tuned control systems, then my question is: what do you think is realistically the farthest distance from the magnetic controller that I could get the globe to stably levitate? Is the limit to that distance reliant on the magnet itself, the electronic controller, or the kind of positional detector (IR, etc) being used?

If this question has an easy answer, then I apologize...I couldn't find one myself, and I don't trust my own knowledge/assumptions to figure out a really good answer myself. Thanks everyone!

submitted by /u/Koh-the-Face-Stealer
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How do you figure out orbital resonance?

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i'm reading this book, nature's numbers, and I can't seem to grasp resonance. He gives an example of mercury, Rotational period - 58.65 days Orbital Period around sun - 87.92 days. He then multiplies 2 x 87.92 = 175.92 and then multiplies 3 x 58.65 = 175.95 showing mercury has a 2:3 resonance. Where does he get the 2 and the 3 to multiply the periods by?

submitted by /u/Jaime_loignon
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Why is Vmax always the same between a competitive inhibiter and a substrate?

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What if the concentration of a substrate greatly overpowers the competitive inhibiters? Or, am I misinterpreting what the velocity represents in a double-reciprical (line weaver Burk) plot?

submitted by /u/please_help_act
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Do beta blockers cause memory loss?

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Just played a game in which a character received a large dose of beta blockers as a child after a traumatic incident. In the game they say this caused entire memory loss relating to the aforementioned incident. Is any of this true? I know beta blockers can cause fuzziness, but could the reaction be this extreme? Or is it just the writers using a vague science term to justify the characters memory loss?

submitted by /u/HuffnPuff165
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How much amount of light is required to perceive colors?

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In a unlit room, it's pitch back to see. say, i have a light source (point) behind me, how much of light, illuminance or intensity, is required, so that i can start to perceive the colors of the objects in front of me? how much light is required for me to properly perceive the colors of the objects?
also, does the amount of light required depend on the size of the light source, position of the light source, distance of the colored objects from the light source/me, the size of the colored objects/room?

submitted by /u/man-i-cure
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Why do we associate certain colors as being good or evil?

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Is the normal force "real"?

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That is to say, is it a force that is distinguishable from the force "pushing" something against another, or is it something that isn't real but makes our model work.

submitted by /u/BrannistheMannis
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How do we know that the Earth's atmosphere used to contain more oxygen than nitrogen in the past?

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How electrons and holes in diodes separate from each other?

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It is easy to understand how electrons and holes recombine in the diode to produce light. But... how is the process for separating them after they have combined?

submitted by /u/Year12
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Is there a way to directly describe the intermolecular forces of water?

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Trying to model the bond forces between water molecules as I increase their temperature. So far the only thing I can find is that the intermolecular forces of a compound effect its boiling point, is there a unit of some sort that I can use to directly describe the force instead of indirect measurements such as viscosity or boiling point?

Also, if it can't be done as a whole because each IMF functions differently then describing them separately or as an average is fine as well.

EDIT: I've come across the fact that it takes 19kJ/mol to break the intermolecular bonds in water, but no site that mentions this seems to explain how that value was (experimentally?) derived.

submitted by /u/Gigahawk
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Do we have any idea what quarks might be made of?

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How much uniforme matter would we need to replace dark matter?

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If we would want to replace dark matter with a standard matter by filling the entire universe's vacuum with one element -- what element would that be, and in what proportion per cm2 of vacuum?

submitted by /u/grisanik
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How does quantum field theory align with/compare to the notion of spacetime?

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I'm getting confused about the relation of the two, if at all. Is space-time a manifestation of all three quantum fields? Is it instead a construct of the theory of relativity that falls apart when we begin to prove the forced actually underlying our universe?

submitted by /u/JimmyTango
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How thick in atoms does carbon need to be to absorb light?

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When a atom absorbs, and transmissions light, I have been told that single atoms are transparent, whatever the element. So how many atoms thick in carbon does it take to completely absorb all wavelength, and frequency of light. Is it basically as you increase the amount of atoms in a crystalline, or non crystalline structure, there is just too many electron absorbing the amount of photons hitting, and getting absorbed by the electrons, and light just cannot get through. The light just gets absorbed weather the material is amorphous, or not. So its only the energy of electron that will let light pass, and transmission through like in glass, and carbon diamond Is this correct. Thank you for your help, anything helps, even a few words.

submitted by /u/gammaknifeedu
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