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Sunday, August 1, 2021

Why does it take 2 weeks for the Covid vaccine to take effect? Would immune-suppressing drugs affect vaccine effectiveness if taken during these two weeks?

Why does it take 2 weeks for the Covid vaccine to take effect? Would immune-suppressing drugs affect vaccine effectiveness if taken during these two weeks?


Why does it take 2 weeks for the Covid vaccine to take effect? Would immune-suppressing drugs affect vaccine effectiveness if taken during these two weeks?

Posted: 31 Jul 2021 10:52 AM PDT

Immune suppressing drugs such as acetaminophen, ibuprofen, alcohol, cannabis etc. (Not seriouser stuff like chemo and steroids)

ETA: I'm wondering specifically about the MRNA vaccines. And I'm referring to common anti-inflammatories like the ones listed, not the immunosuppressive drugs used in cancer treatments or organ transplants.

ETA2: I don't know why comments keep getting deleted. I'm not the one deleting them???

submitted by /u/PRODUCTIVEstoner94
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Why are Marie Curie's possessions kept in lead boxes?

Posted: 31 Jul 2021 09:35 PM PDT

I keep seeing posts like this saying her body and belongings are so radioactive that they're kept in lead boxes. The Radium isotope with the longest half life is Ra256, which is an alpha emitter. The longest lived Polonium isotope has a half life of 4 months and is also an alpha emitter. She worked with Uranium and Thorium - much longer lived but also alpha emitters. So you should be able to store them in a cardboard box - you just don't want to handle them in ways that might cause you to ingest or breathe in radioactive material. So what are they contaminated with that requires a lead box?

submitted by /u/jns_reddit_already
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When did the most recent common ancestor of coronaviruses and influenza viruses exist?

Posted: 31 Jul 2021 01:02 PM PDT

In some quarters comparisons between covid and the flu have been taken so far as to claim that covid is a flu. Such claims seem patently incorrect, as the viruses belong to different taxa - but just how wrong is it? Would it be comparable to claiming that cats are dogs, or more akin to equating cats and nematodes?

I'm assuming here that all viruses have a shared ancestry, as it seems to be the case for all organisms conventionally considered alive (bacteria, archaea, eukaryotes). Do we know for sure that this is the case for viruses, or is it possible that they appeared more than once?

submitted by /u/PhysicalStuff
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How do forbidden quantum transitions happen?

Posted: 31 Jul 2021 03:02 PM PDT

Ok, so I majored in (bio)chemistry and work in chemistry for my job. I have an introductory knowledge of quantum physics and how it is different from classical models, but not a deep mathematical understanding. One thing that spectroscopists mention often is "forbidden" quantum transitions. I gather that these are supposedly against the rules of physics, so in my understanding they should never occur, but they very much do. So, they are much longer lived quantum states because of their "forbidden" nature disallowing an "allowed" path to relax back to ground state, but they still manage to do so, but slower. I don't understand how something can be against the laws of physics and still happen. Wouldn't that imply that our understanding of what's happening incomplete and we need a better model?

submitted by /u/Notorius_Nudibranch
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Why do high pressure cylinders most often have rounded bottoms?

Posted: 31 Jul 2021 11:51 AM PDT

Is it reliant on the way they're manufactured?

submitted by /u/quadmasta
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Have any typical brain fog treatments been studied for people who have covid-induced brain fog?

Posted: 31 Jul 2021 04:25 PM PDT

It's my understanding that brain fog can be caused by a variety of different things. Some people with ADHD, CFS, etc. experience brain fog. Brain fog can also appear due to lack of sleep, illness, etc.

It's also my understanding that treatments like amphetamines (Adderall) can usually effectively reduce brain fog symptoms, regardless of cause.

So my question is has anyone studied the effect of amphetamines or other stimulants on covid brain fog?

submitted by /u/dc2b18b
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Is your risk of developing myocarditis from the COVID-19 vaccine greater if you have been previously diagnosed?

Posted: 31 Jul 2021 09:48 AM PDT

How is sea level throughout geologic time determined?

Posted: 31 Jul 2021 07:39 PM PDT

Many geologists since the dawn of sequence and seismic stratigraphy have attempted to craft sea level curves for the last 540 million years (Phanerozoic). How are these made? Is it a matter of calculating the proportion of marine vs. continental sedimentary units in a specific place? Or does it have to do with systems tracts?

submitted by /u/jesus-chrysocolla
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We often hear about the fastest land animal on Earth being the cheetah. But what would the fastest land animal be over a distance of a marathon? How high would the top human runners rank?

Posted: 30 Jul 2021 05:24 PM PDT

How long does live prey live in the gullet of a predator for, and what is the cause of death?

Posted: 30 Jul 2021 04:49 PM PDT

I'm thinking of live prey that has been swallowed whole without envenomation, as in a pelican swallowing fish.

submitted by /u/Stonius123
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Why does weather radar only use one spinning dish?

Posted: 30 Jul 2021 04:56 PM PDT

I get that it only scans one line so it needs to sweep to get a complete picture, but that means that the sampling rate for any given direction is equal to the RPM of the dish. So why not have 3 dishes 120 degrees out of phase so you get an effective sample rate of 3 times the RPM? I would imagine in meteorology the finer resolution you could achieve would have a great effect on accuracy?

submitted by /u/showponies
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If sleep cycles are approximately 90 minutes, why is the recommended amount of sleep 8 instead of 9 hours?

Posted: 30 Jul 2021 09:56 AM PDT

Basically title. Five 90 minutes cycles would be 7 hours 30 minutes, and six 90 minute cycles would be 9 hours. Is there any reason 8 hours of sleep is the decided upon number? Or just good 'middle ground'?

Thanks!

submitted by /u/mxlun
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Saturday, July 31, 2021

Question - Is there a study comparing the Gamma and the Delta variant?

Question - Is there a study comparing the Gamma and the Delta variant?


Question - Is there a study comparing the Gamma and the Delta variant?

Posted: 30 Jul 2021 02:11 PM PDT

So, I live in Brazil, and back in January we had what some people call "COVID-19 hell". It was the P1 (Gamma variant) rampaging the country. I think we were the most heavily hit country in the world.

Then, today, I read about some documents that puts the delta = R0 5-8, which seems a lot. From what I understand, it's a lot more transmissible than the Alpha, the UK one.

My question is, unlike most countries, we had a lot of trouble with a variant that is worse than the B.117 already. Are we less likely to have a giant surge, like some countries are having, because of the P1?

I searched everywhere and didn't find any comparison between the Gamma and the Delta R0 numbers.

Thank you very much

submitted by /u/JackyeLondon
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What are the mathematical and universal implications behind the “unsolvable” Collatz Conjecture?

Posted: 30 Jul 2021 09:18 AM PDT

The Collatz Conjecture;

https://en.m.wikipedia.org/wiki/Collatz_conjecture

Choose any number. If it's even, divide it by two. If it's odd, multiply it by three, then add one. Follow this pattern as long as possible.

Essentially, as far as we can tell, any number that follows this basic formula will eventually end up at one, which makes four, then two, then one again. In an endless loop. And we can't prove why.

My question is less about what the answer is, and more about what the implications of a strangely "unsolvable" could be in terms of our physical universe? Because as we know, mathematics correlates with our physical reality.

submitted by /u/BSIBooker
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Are there vaccines that gives sterilizing immunity?

Posted: 31 Jul 2021 02:15 AM PDT

Are they the majority of vaccines? The minority?

submitted by /u/wanttosellstufffs
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Why & How Do Clay Minerals Swell When Wet?

Posted: 30 Jul 2021 10:53 AM PDT

What is unique about clay minerals that causes them to swell or expand when saturated with water? Is the process primarily mechanical or chemical in nature?

submitted by /u/37litebluesheep
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How do scientists date items that are hundreds of thousands of years old with little to no carbon content?

Posted: 30 Jul 2021 04:33 AM PDT

As the title says I Was reading this article and wonder how you date rocks? I'm familiar with how carbon dating works but, how do they do it when the item has no carbon content?

Article in Question

submitted by /u/M3ttl3r
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Can particles decay by weak self-interaction?

Posted: 30 Jul 2021 01:27 AM PDT

It seems like a simple question, at least if you are familiar with the topic, but I just can't find a concrete answer anywhere.

So, could a D+ (c & anti-d), or any other suitable particle really, decay into an anti-Kaon (s & anti-d) positive pion (u & anti-d) simply by a weak self-interaction of the c-quark? What I imagine is c "temporarily" transitioning into a d/s-quark and then finishing the self-interaction by turning into an s-quark. Does this violate some kind of conservation law or is this a reasonable decay mode?

submitted by /u/SkipX
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How can a mushroom die?

Posted: 29 Jul 2021 02:23 PM PDT

The mycelium can measure several kilometers, I don't see how it can be completely destroy

submitted by /u/Vantaie
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Friday, July 30, 2021

AskScience AMA Series: We invented a better version of CRISPR. Ask us anything!

AskScience AMA Series: We invented a better version of CRISPR. Ask us anything!


AskScience AMA Series: We invented a better version of CRISPR. Ask us anything!

Posted: 30 Jul 2021 04:00 AM PDT

We are CRISP-HR Therapeutics, Inc., an early stage biotech company which has developed a dramatically improved CRISPR-based genetic engineering platform, Cas9-HR. The improvements include increased editing efficiency enabling previously unfeasible large edits (1000s of base pairs) at a clinically viable level, in addition to lower cellular toxicity. Our Cas9-HR Platform represents an exciting step for gene editing.

We plan to use our Cas9-HR Platform to develop therapeutics, specifically treatments for genetic diseases that are caused by a diverse number of mutations. Since existing high-efficiency CRISPR technologies are limited to small edits (1-50 base pairs), we believe this is an area where we can make a significant impact.

Answering questions today are the two co-founders:

  • Chris Hackley, PhD, CEO: /u/chris-hackley-chr: Chris has 11+ years experience in a variety of biological areas, with particular expertise in protein and genetic engineering. Chris earned his BS in MCD Biology from UCSB, and PhD in protein engineering from NYU.
  • Richard Gavan, MSc, CTO: /u/richard-gavan-chr: Richard has 8+ years experience consulting in IT for the life sciences industry. Richard earned his BA in Philosophy and Psychology from UCSB, and MSc in Computer Science from Georgia Tech (OMSCS).

We'll start answering questions at 19:00 UTC (8pm BST, 3pm EDT, 12pm PDT) on Friday, July 30th. We're looking forward to hearing from you!

submitted by /u/AskScienceModerator
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Is sleep debt from accumulated sleep loss real according to current understanding?

Posted: 29 Jul 2021 11:11 AM PDT

Hi! I'm trying to learn about sleep debt and what are it's limits. I found some questions in this subreddit, but they are from many years ago, and I was wondering about the current understanding/latest studies in the subject. And wether or not it is an accepted theory.

I saw a lot of info about complete deprivation of sleep (all nighters). But I'm more interested in chronic sleep loss and subconcious sleep deprivation. For example, if my body naturally needs 8 hours of sleep, and I sleep 7 for months, with some days of 6 hours splashed around, how would that affect my sleep debt and how could I recover?

How much sleep is needed to recover from a months old accumulative sleep debt? Is a few days of unrestrained sleep enough? Or are multiple days of extra sleep across a longer span of time required?

submitted by /u/damipereira
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Do beavers instinctively know how to build dams, or do they learn it from other beavers? If it's instinctual, are there any tools or structures that humans instinctually know how to make?

Posted: 29 Jul 2021 10:43 AM PDT

Why is light attracted to black holes if it has no mass?

Posted: 29 Jul 2021 09:59 AM PDT

Does light have mass? Because how can it be pulled by gravity without mass?

submitted by /u/aerglos
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Is there an index which identifies the most habitable geographies?

Posted: 30 Jul 2021 06:10 AM PDT

Out of all of the livable geographies on Earth, I expect some should be more condusive to civilisation. Whether it is easier access to more natural resources, more fertile land, temperate climate, less geologically active, less chance of flooding or drought, or easier access by land, it's clear that a lot of factors are at play. Is there an index to rank the most habitable places for humans, or an index to estimate the human carrying capacity of a land area?

submitted by /u/Aerothermal
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There is increasing evidence that COVID-19 affects the brain. Is there a similar effect for other coronaviruses (like the ones that cause the common cold), or is it specific to SARS-CoV-2?

Posted: 30 Jul 2021 04:15 AM PDT

What is the protection status for the Russian Sputnik and the Cuban Vaccine compared to moderna, Pfizer, Johnson and astrazeneca?

Posted: 29 Jul 2021 02:34 PM PDT

I can't seem to find statistics and comparable numbers.

submitted by /u/klyde_donovan
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When studies are suggesting that the Pfizer vaccine's efficacy drops after six months, how do they measure this?

Posted: 30 Jul 2021 06:00 AM PDT

Are they looking at infections/severe illness in vaccinated people on a population level, or are they measuring the amount of antibodies people have 6+ months after getting the vaccine? Could it be the case that, although antibodies decline, B and T cells can still offer long lasting protection?

submitted by /u/jqycer
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How did genes causing myopia survive evolution?

Posted: 30 Jul 2021 02:19 AM PDT

Myopia is highly heritable and is very common - over 40% of Americans and 80% of asians have some extent of myopia, how did early humans survive without glasses? How were they able to pass on these genes which contribute to myopia?

submitted by /u/ambivalent-koala
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if the deepest a modern nuclear attack submarine can go in the ocean is 2500 feet down before its hull collapses, how do animals survive that deep and deeper?

Posted: 29 Jul 2021 10:58 AM PDT

You're staring up at the night sky. You pick a faint star and stare at it and it all but disappears. You look away and it reappears, or at least brightens, in your peripheral vision. Why?

Posted: 29 Jul 2021 09:00 PM PDT

After reading a Kff.org report on US COVID-19 vaccination rates by race/ethnicity (data pulled from the CDC), why is the vaccine adoption rate so low among Hispanics/Blacks?

Posted: 29 Jul 2021 03:56 PM PDT

Is this more of a cultural disparity? or a socioeconomic issue? Report in question: https://www.kff.org/coronavirus-covid-19/issue-brief/latest-data-on-covid-19-vaccinations-race-ethnicity/

submitted by /u/blood_vein
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How did the recent 8.2 Earthquake in Alaska generate almost no tsunami?

Posted: 29 Jul 2021 11:34 PM PDT

Why is the wildfire smoke in North America gathering in central Minnesota?

Posted: 29 Jul 2021 09:38 AM PDT

I live in central Minnesota and for some reason we are having the worst time with the smoke from the wildfires across the country gathering here. Can anyone explain why this is?

submitted by /u/Oneofthosemegans
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What is the body’s reaction to donating a pint of blood?

Posted: 29 Jul 2021 07:51 AM PDT

I donate blood regularly. I understand your body is constantly regenerating red blood cells and iron to replenish.

Does it work "overtime" because it senses a larger deficit after donation?

And wouldn't my hemoglobin amount go down for awhile resulting in more fatigue because "I'm down a pint?"

They also test me for ferritin to ensure I have enough iron after every 3rd donation.

Can someone explain the biological process here? Thanks!

submitted by /u/2DamnRoundToBeARock
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Thursday, July 29, 2021

AskScience AMA Series: We Are Scientists Studying Microbes in Outer Space. Ask Us Anything!

AskScience AMA Series: We Are Scientists Studying Microbes in Outer Space. Ask Us Anything!


AskScience AMA Series: We Are Scientists Studying Microbes in Outer Space. Ask Us Anything!

Posted: 29 Jul 2021 04:00 AM PDT

What can microbiology tell us about life on Earth (and beyond)? Quite a lot, actually. Whether searching for extraterrestrial life, understanding the impact of extreme conditions on humans or expanding human presence in space it is the smallest life forms that are central to answering some of our biggest questions. Join us today at 2 PM ET for a discussion, organized by the American Society for Microbiology (ASM), of all things space microbiology. Some of the projects we are working on include:

  • Microbiomes in space
  • Effects of microgravity on animal-bacterial symbioses
  • Detection of life on other planets
  • Microbial contamination on crewed space flights
  • Role of microorganisms in space exploration
  • BioRock and BioAsteroid, two space biomining experiments run on the International Space Station

We are:

Ask us anything!

Links:

submitted by /u/AskScienceModerator
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Why do we not see deadly mutations of 'standard' illnesses like the flu despite them spreading and infecting for decades?

Posted: 29 Jul 2021 03:11 AM PDT

This is written like it's coming from an anti-vaxxer or Covid denialist but I assure you that I am asking this in good faith, lol.

submitted by /u/Poseidon1232
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What happens at a chemical level when a bottle of liquor is allowed to "rest"?

Posted: 28 Jul 2021 08:45 AM PDT

I'm curious about this and don't really see it addressed elsewhere. It's become common to allow a bottle of liquor (whisky, cognac, etc) to "rest" after opening. In fact, I just read this in a vodka review: "It is Beluga's philosophy to have this vodka rest after each step of the production," explains Borisov. After a five-time filtration process to achieve maximum smoothness, the vodka's final resting period is 90 days. "This allows it to reach perfect balance and harmony,"

Since I always like to ask myself "why is that" and "what mechanism is at work here", I'm asking precisely that. Is there some chemical change happening to drive a flavor shift or is this "resting" of a seemingly stable substance mostly psychological in nature. If a sealed or capped bottled is allowed to "rest" sans additional oxygen or heat, how is it changing?

submitted by /u/cornmuse
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Since water displaces energy evenly throughout its body, could you survive a long fall by being in a mid-air body of water or a container full of it? My 9 year old asked me something similar to this and I didn't have an answer.

Posted: 28 Jul 2021 01:13 PM PDT

EDIT: This got a lot bigger than I exected. Wow! Hard to believe a casual conversation from DND lead to this. I want to thank everyone who has answered and responded. There is a lot of science to learn here and I am grateful for all of it!

submitted by /u/archblade7777
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Setting aside absorption and swallowing, would swimming in a pool of alcohol be considerably more or less difficult?

Posted: 28 Jul 2021 05:08 PM PDT

Does having repetitive hypoglycemia result in permanent brain damage (reduced memory and intelligence)?

Posted: 29 Jul 2021 08:06 AM PDT

WebMD states:

Studies tie diabetes to proteins in your brain that are linked to dementia. Because of narrowed, hardened arteries, your chances of stroke are also higher. Your brain needs sugar to do its job. Repeated bouts of low blood sugar can damage the brain.

I was not able to find anything else regarding this online.

submitted by /u/Aetherxy
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Genuine question: how do they know when it’s the Delta variant or not if they’re not exclusively testing for it?

Posted: 28 Jul 2021 04:39 PM PDT

So I've seen on multiple TikToks (not a good source at all) that most facilities aren't testing specifically for the delta variant but testing random samples to see if it is. Obviously, I'm not stupid so I wanted to see if there was validity in this and when I looked it up, most sources were saying that they can't discern the difference between traditional COVID and the delta COVID.

I even went as far as to call my local COVID hotline and they did not have an answer either.

I'm vaccinated and have always followed the facts but I just want to know how they know it's delta that's surging, or is it just COVID in areas where vaccination rates are low?

submitted by /u/EdenTrails23
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What is the likelihood of some sort of coral reef migration in the event that ocean temps continue to rise?

Posted: 29 Jul 2021 12:15 AM PDT

So, we are seeing mass bleaching events in reefs due to temperatures rising. With a continual rise, could other, previously colder, places end up transforming into coral reefs or is this unlikely?

I get the odds are stacked against them seeing that they're sessile, slow growing, temperamental, etc. but through some miracle of nature or human intervention like mariculture, could coral free zones become inhabited?

submitted by /u/GordonRammstein
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Is there any link between density and viscosity of a fluid? Does the density of a liquid influence how viscous a fluid is our vice versa?

Posted: 29 Jul 2021 05:38 AM PDT

If herpes isn't a retrovirus, why is it impossible to cure?

Posted: 28 Jul 2021 10:08 PM PDT

I know that HIV establishes a latent reservoir by integrating into the host genome. But to my understanding, HSV doesn't do that, so how does it remain in the body such that it can't be cured?

What are the approaches currently being considered to try and cure HSV, if there are any efforts? How would one test whether or not the virus has been cleared/in HSV or in general?

submitted by /u/hottiewannabe
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Nuke detonating in space?

Posted: 28 Jul 2021 01:05 PM PDT

There are a handful of alien related movies (Avengers is what brought this to mind) where a Nuclear Bomb is detonated in space.

When a nuke goes of in atmosphere, the shock wave is what transfers mechanical energy to cause a large portion of the destruction that ensues, and you actually get much more damage with the bomb detonating a few hundred feet above ground, instead of actually impacting.

What would happen during a detonation in space, in near vacuum? Different effects for if it actually struck an object, vs detonating near it?

submitted by /u/RumpusTheRat
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Does the Delta variant's increased viral load in the nasopharynx make antigen tests less likely to give a false negative, even in asymptomatic cases?

Posted: 28 Jul 2021 10:11 PM PDT

Many scientists are saying that the Delta variant causes there to be around 1000x more virus present in the nasopharynx of people than previous strains of SARS-CoV-2, even in breakthrough infections.

There is also data from earlier in the pandemic explaining that there is a significant likelihood of false negative test results from rapid antigen tests, especially in asymptomatic carriers.

So I am curious about whether or not the Delta variant's increased viral load will decrease the rate of false negative test results from rapid antigen tests. In other words, could the trait (higher viral load) that makes Delta more transmissible help improve the sensitivity of rapid antigen tests?

submitted by /u/StrawberrySunscreen
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On their website, Sputnik says their vaccine is “proven to have no risk of carcinogenicity”. How can they possibly know this?

Posted: 28 Jul 2021 11:20 PM PDT

Of course I hope it's true, but how do they know? Is this true of all vaccines?

submitted by /u/Ok_Cap105
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If a vaccine is mistakenly injected below the deltoid muscle and/or into the shoulder capsule, does the desired immune response still take place, or is it lessened?

Posted: 28 Jul 2021 12:00 PM PDT

Is it possible to still have immunity to a pathogen you were previously infected with, even if an antibody blood test comes back negative?

Posted: 28 Jul 2021 10:41 AM PDT

As far as I understand it after being infected with a pathogen your body produces memory cells, which will stimulate production of antibodies if the pathogen is re-encountered. Is this reasoning correct?

submitted by /u/BenBerspanke
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Why is the Maclaurin’s Series inaccurate for functions like In(1+x) but is extremely accurate for functions like sin(x)?

Posted: 28 Jul 2021 06:57 AM PDT

The title says it all basically. I am taking A-Level Further Mathematics and while studying this topic I was confused as to why the Maclaurin's series was accurate for some functions but inaccurate for others. It turned out to be spot on for sin(x) and (1+x)" but when I tried to see the series I generated for In(x+1) was accurate, it turned out to be extremely inaccurate, the inaccuracy increasing as I computed more terms.

For clarification, the Maclaurin's Series I generated was:

x-1/2x2+1/3x3-1/4x4.....

Thanks in advance for any help on this matter🤗

submitted by /u/The-eff
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With what we know now in 2021 compared to 2020, how can vaccine makers design newer vaccines that are more effective against COVID variants?

Posted: 28 Jul 2021 12:50 PM PDT

Do vaccine designers simply make vaccines that produce spike protein antigens with the mutations similar to newer variants or is there any other new technology that can be used to improve vaccination performance against variants?

submitted by /u/Tywin____Lannister
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How do scientists find out how old are certain fossils? What is the process?

Posted: 28 Jul 2021 10:49 AM PDT

Honestly just curious on how a scientist can find a dinosaur bone and say it is so so old.

submitted by /u/Skyline2374
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Is There a Greater Quantity of Dark Matter Than Baryonic Matter in the Universe? Or Is It Just More Massive?

Posted: 28 Jul 2021 09:05 AM PDT