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Friday, December 11, 2020

How did the Australian coronavirus vaccine produce HIV antibodies?

How did the Australian coronavirus vaccine produce HIV antibodies?


How did the Australian coronavirus vaccine produce HIV antibodies?

Posted: 11 Dec 2020 04:01 AM PST

The Australian vaccine effort has been halted after it produced HIV antibodies, leading to a false positive for HIV. Why did a coronavirus vaccine do this?

https://www.bbc.co.uk/news/world-australia-55269381

submitted by /u/enduroalpha
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Was the 1918 pandemic virus more deadly than Corona? Or do we just have better technology now to keep people alive who would have died back then?

Posted: 10 Dec 2020 09:01 AM PST

I heard the Spanish Flu affected people who were healthy harder that those with weaker immune systems because it triggered an higher autoimmune response.

If we had the ventilators we do today, would the deaths have been comparable? Or is it impossible to say?

submitted by /u/rob132
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Will plasma from vaccine recipients be as effective of a therapeutic as plasma from those previously-infected?

Posted: 11 Dec 2020 03:20 AM PST

I've heard (anecdotally) that giving critical patients plasma from someone who has recovered from COVID-19 seems to be a very helpful treatment. Presumably, this plasma is in short supply. Should vaccine-recipients be similarly encouraged to donate plasma? Would the plasma from the vaccinated be as effective or more effective of a treatment?

submitted by /u/jaramini
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How does sleep deprivation cause hallucinations/paranoia/etc.?

Posted: 10 Dec 2020 10:21 PM PST

What part of the brain does it affect? How does sleep do anything? How does it work?

submitted by /u/_star_sailor_
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Does Alzheimer's merely hinder access to memories through destroyed pathways, or does it destroy stored memories, or is it a mix of both?

Posted: 10 Dec 2020 08:34 PM PST

Does water cool down and warm up at the same rate?

Posted: 11 Dec 2020 04:06 AM PST

Example of what I mean: say the ambient room temperature is 25C, I have a two glasses of water, one at 20C and the other 30C. Will the two glasses reach 25C at the same time?

submitted by /u/r_plantae
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How exactly is limestone (calcium carbonate specifically) formed?

Posted: 10 Dec 2020 10:20 PM PST

Is calcium carbonate only formed biotically like in the case of coral and seashell creatures, or is there a way to form it abiotically? How is there so much limestone inland? Was that formed abiotically or was it left there by ancient oceans or uplifting or something?

submitted by /u/newdogc
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If rocks and fossils are millions of years old, how come whenever there is a comet crater there isn't anything there anymore?

Posted: 10 Dec 2020 08:51 AM PST

Excuse the non-scientific explanation. I have always wondered why comets aren't still in the ground and there is only a crater there. Does the comet rock matter get broken down quicker in earth's atmosphere? And the minerals in rock produced in the earth's core out live the comet? I'm baffled

submitted by /u/YairleyD
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Are we able to isolate, store and accumulate neutrons?

Posted: 10 Dec 2020 10:35 PM PST

Few questions come to mind: what vessel/container could even hold a subatomic particle? And I assume neutrons are stable and inert, but, outside of an atom, are they?

What really drove me to ask this is, what's a pile of (free) neutrons like?

submitted by /u/rancid_oil
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Why does one side of the moon always face Earth?

Posted: 10 Dec 2020 11:10 AM PST

What happened in the past to make this occur?

submitted by /u/A_western_story
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What Does Blue and Red Shift mean?

Posted: 10 Dec 2020 03:35 PM PST

I searched it up but i guess you could say im not the sharpest tool in the shed so didnt really understand it. so can you geniuses dumb it down for me?

submitted by /u/pw3x
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String can never be fully horizontally in centripetal motion?

Posted: 10 Dec 2020 08:54 PM PST

I did a lab in my AP physics class where we spun a rubber stopper on a string in a horizontal circle. However, I was wondering how the fact that the string pulling the stopper isn't fully horizontal creates errors in the experiment. I know the tension force has an upward component to counteract gravity does this affect the radius? What errors does the string not being perfectly horizontal cause? Thanks in advance!

submitted by /u/nikki3335
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Why don't magnetic fields expelled by solar flares behave like light?

Posted: 10 Dec 2020 03:44 PM PST

I was just reading this news article about how the Northern Lights might be visible in Oregon tonight because of a solar storm: https://www.cnn.com/2020/12/09/us/northern-lights-display-wednesday-night-scn/index.html

The article states that a solar flare already happened on 12/7. Why aren't the magnetic fields created by the solar flare here already--i.e. why didn't they travel at the speed of light? Isn't it all EM radiation?

submitted by /u/Artrw
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Will virus-transmission increase exponentially or just marginally when people are simultaneously co-infected with two infectious diseases?

Posted: 10 Dec 2020 06:53 PM PST

Currently we are in the midst of influenza season as well as a global pandemic.

I understand that it is possible that a person can be infected by both COVID and the influenza strain at the same time. That brings us to my question about co-infections.

Covid and the flu, share a lot of the same symptoms that spread infections, with the flu having runny noses as a symptom too. How would this affect transmission ratse when the populace is infected with both the flu and covid?

Would the R0 factor raise dramatically or only marginally? Especially if we take in account that both diseases are mutually spreading each other.

submitted by /u/GetOutOfTheWhey
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Can a self-replicating vaccine run wild in the body?

Posted: 10 Dec 2020 07:46 AM PST

After I heard some vaccines are self-replicating, the question hit me. What keeps the mRNA from entering every single cell in the body? Is that even a problem if it does? It only changes the outer shell of the cell?

I have no clue about biology other than what's taught in high school.

submitted by /u/tonivuc
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What is the average number of deaths per day (all causes) in the US and is it clear the pandemic has increased the average deaths per day?

Posted: 10 Dec 2020 06:17 PM PST

First I must be clear I am not a denier of the pandemic. It seams that those that believe COVID deaths are fake may be swayed by a chart showing a substantial increase in overall deaths per day over previous years. I have been unable to locate such a magical chart. Thoughts? If this is not the right place to ask this question I would love to get a recommendation for another sub.

submitted by /u/OnceOccupied
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Why does Genetic Anemia effect Asian and African families more?

Posted: 10 Dec 2020 04:35 PM PST

Why are genetic anemia conditions more common in Asian and African families?

Thalassemia runs in my family and the internet says that it is most common in Chinese people.

Why does race have an effect on this?

submitted by /u/Hyde1803
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How significant is age-related (not including disease related, e.g. Alzheimer's) cognitive decline and at which ages?

Posted: 10 Dec 2020 03:35 PM PST

The combination of current age-related political discussion and watching my own parents' mental progress over the last 15 years or so has me thinking about the statistics of age-related cognitive decline. Obviously there is likely to be a distribution among populations, but I think we can all agree it's unusual for someone in their 80s or 90s to have the same mental acuity they had in their 40s.

How much science is there behind this?

submitted by /u/N8CCRG
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What is the fate of hypoblast?

Posted: 10 Dec 2020 11:32 AM PST

I am a little confused about the formation of endoderm and the fate of hypoblast. I understand that epiblast cells migrate through primitive streak to form mesoderm/notochord. I also understand that ectoderm arises from epiblast.

Do mesoderm cells replace hypoblast cells and form endoderm or do hypoblast cells just differentiate into endoderm?

Also an additional question is, do the hypoblast cells line the whole yolk sack? If yes, does hypoblast line the yolk sac even after formation of the endoderm, mesoderm and ectoderm?

submitted by /u/bbxmiz
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Are things in our peripheral vision distorted?

Posted: 10 Dec 2020 03:05 PM PST

I was wondering if there was any impact on our vision due to the curvature of our eyes, similar to how a map is distorted due to the projection of a 3D image on a 2D surface. Am I thinking this out correctly or does the curvature of our eyes contribute to us being able to see in three dimensions?

submitted by /u/LockedLemming90
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Thursday, December 10, 2020

A vaccine is 94% effective. What, exactly does that mean?

A vaccine is 94% effective. What, exactly does that mean?


A vaccine is 94% effective. What, exactly does that mean?

Posted: 09 Dec 2020 09:23 PM PST

Does that mean a vaccinated person, exposed 100 times, will be fine 94 times? Or does that mean the severity of the resulting disease is reduced by 94%? or does that mean that 94% of subjects are 100% immune for this disease for a period of time?

submitted by /u/RusticSurgery
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If Quarks are Color Confined and likely stable, how can a proton decay? Am I missing something important?

Posted: 10 Dec 2020 03:48 AM PST

So grand unified theories predict proton decay, but how exactly? Aren't the Quarks color confined and stable? Plus, protons are the lightest baryon... I feel I'm missing something important

submitted by /u/Birds_106
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At what age will kids be treated differently in terms of getting the vaccine? Somewhere between adult and newborn should be a “too young for the vaccine” in the first year, but what age is that?

Posted: 10 Dec 2020 01:50 AM PST

I read that it might be 16 years and older. In later years maybe we can assume younger ages as more data is available but in the first year what is likely?

submitted by /u/mbergman42
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Epidemiologist, What is the impact of covid 19 on people with tuberculosis especially those with latent TB? like could it cause the diseases to become active or not.

Posted: 09 Dec 2020 08:36 PM PST

Could you sequence the dna of cancer cells and then compare it to the persons healthy cells to locate the genetic mutation and then edit the dna of the cancer cells causing new cells to just be normal again?

Posted: 10 Dec 2020 12:51 AM PST

What are the Cellular effects of Spike Proteins binding to the ACE2 receptor?

Posted: 09 Dec 2020 08:07 PM PST

With all the news regarding the new mRNA vaccines for covid floating around it has left me with a few questions I can't seem to find answers to online based on my search terms.

  1. Can the Spike Proteins created by the mRNA activate the ACE2 receptor? If it can activate the receptor, what impact would this activation have and how long would the protein stay bound to the receptor?
  2. Can mRNA degrade or become damaged and still be translated by the ribosomes? If damaged mRNA can be transcribed, would this allow for the possibility of an incorrect protein being created?

Disclaimer: Not Anti-vax, Just curious

submitted by /u/entropreneur
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Do we have any info/data on the types of medical conditions that may preclude someone from being able to take any or all of the COVID-19 vaccines currently on the horizon?

Posted: 09 Dec 2020 10:36 AM PST

I know that some people with certain medical conditions ultimately rely on herd immunity vs physically getting vaccines, due to increased risk of medical complications. Do the upcoming vaccines pose that same risk to certain patients?

submitted by /u/gingerblz
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What will happen to the frequency and wavelength of the sound wave if we directly change the speed of sound? How will they change?

Posted: 10 Dec 2020 01:01 AM PST

Since v= λ f and we know that f and λ are inversely proportional so changing one of them would not change the velocity but decrease the other. So if we directly change the velocity how will they change?

submitted by /u/Ok_Yam_9154
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Is there any fear among the scientific community that SARs-CoV-2 might mutate into different strains that are either harder to vaccinate against or are more deadly/communicable?

Posted: 09 Dec 2020 11:59 PM PST

I had this thought while looking at a world map of infections today and musing on how similar it looked to the "pandemic" game some of you may have played, where the best strategy is often to infect as many people as possible with your virus before mutating and rapidly wiping out humanity.

I don't expect this to happen, but it did raise the question for me above. I found this article from August of this year that provided good information, but I was wondering if there was any other research you guys are aware of, if this is an active topic of discussion, or if it's mostly a non-concern at this point.

Thank you.

submitted by /u/Professional-Ad-2031
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¿How can the CMB be sphere-shaped?

Posted: 09 Dec 2020 10:07 PM PST

I know the popular image of the CMB is a Mollweide protection from a sphere... But what does the sphere shape mean? Isn't this radiation supposed to come from everywhere? This implies that there is some kind of "center" or origin? If this is not the case, then why does it form a sphere? Or maybe I am simply misinterpreting the information and there is no sphere at all.

Thanks! Sorry if this question sounds dumb but I'm really curious to understand why the CMB is represented like that. Have a good day and stay safe.

submitted by /u/HombrexGSP
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Are there ways to estimate how many people have coronavirus in a population, given its testing numbers and positive rate?

Posted: 09 Dec 2020 01:32 PM PST

Is there something like an equation I can plug and chug numbers into, where for X population size, Y testing rate, Z positive rate, there are probably W undiagnosed covid patients in the population?

submitted by /u/idzero
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Why is it that the circumference of a circle is the derivative of its area and the surface area of a sphere is the derivative of its volume?

Posted: 09 Dec 2020 01:21 PM PST

If there’s a limited number of vaccines immediately available, why not test groups set to receive the first doses for antibodies and first vaccinate those without antibodies?

Posted: 09 Dec 2020 10:33 AM PST

Why isn't Batrachotoxin an Antitoxin to Tetrodotoxin?

Posted: 09 Dec 2020 11:14 AM PST

So, I've heard, that Tetrodotoxin and Batrachotoxin have contrary effects on the body, so therefore Tetrodotoxin is used as an Antitoxin for Batrachotoxin, however I've looked up Antitoxins for Tetrodotoxin and there is none, so why isn't it possible for this to work the other way around, or if it does, why isn't it done?

submitted by /u/BADorni
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Why isn’t there DNA in hair except at the roots?

Posted: 09 Dec 2020 04:52 AM PST

If the COVID vaccine teaches our immune system to attack COVID’s spike protein that binds to ACE2, won’t the immune system also attack angiotensin II which was originally meant to bind to ACE2?

Posted: 09 Dec 2020 09:52 AM PST

Wednesday, December 9, 2020

If 2/3 of the American adult population gets the covid vaccine will that: 1: lead to heard immunity 2: make it so children don’t necessarily need the vaccine to return to normal life?

If 2/3 of the American adult population gets the covid vaccine will that: 1: lead to heard immunity 2: make it so children don’t necessarily need the vaccine to return to normal life?


If 2/3 of the American adult population gets the covid vaccine will that: 1: lead to heard immunity 2: make it so children don’t necessarily need the vaccine to return to normal life?

Posted: 09 Dec 2020 07:01 AM PST

I'm not trying to avoid giving my child the vaccine. I am pro vaccine. I just know there haven't been studies yet and it's a while out. Looking for a little hope.

Edit: clarity. I was in a covid vax trial. Check my history and stop messaging me to say I'm a bad parent. I LOVE VACCINES.

submitted by /u/literallyfromjupiter
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Will the Covid vaccine go to people that have caught Covid already?

Posted: 09 Dec 2020 12:33 AM PST

Since the vaccine just gives your body a little piece (mRNA) of the virus would catching the actual virus do the same thing for your body? Making people that have caught Covid and survived immune to the virus since their body has already dealt with the virus and knows what to look for.

I remember around June - July that nobody was sure if you became immune once you caught Covid. but with this vaccine and how it works, it would make sense that you would be immune after catching covid. So with that, has anyone heard of "Covid survivors" getting the vaccine? Or am I wrong in thinking you'd be immune after catching Covid?

submitted by /u/kylepenn10
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Ask Anything Wednesday - Physics, Astronomy, Earth and Planetary Science

Posted: 09 Dec 2020 07:00 AM PST

Welcome to our weekly feature, Ask Anything Wednesday - this week we are focusing on Physics, Astronomy, Earth and Planetary Science

Do you have a question within these topics you weren't sure was worth submitting? Is something a bit too speculative for a typical /r/AskScience post? No question is too big or small for AAW. In this thread you can ask any science-related question! Things like: "What would happen if...", "How will the future...", "If all the rules for 'X' were different...", "Why does my...".

Asking Questions:

Please post your question as a top-level response to this, and our team of panellists will be here to answer and discuss your questions. The other topic areas will appear in future Ask Anything Wednesdays, so if you have other questions not covered by this weeks theme please either hold on to it until those topics come around, or go and post over in our sister subreddit /r/AskScienceDiscussion , where every day is Ask Anything Wednesday! Off-theme questions in this post will be removed to try and keep the thread a manageable size for both our readers and panellists.

Answering Questions:

Please only answer a posted question if you are an expert in the field. The full guidelines for posting responses in AskScience can be found here. In short, this is a moderated subreddit, and responses which do not meet our quality guidelines will be removed. Remember, peer reviewed sources are always appreciated, and anecdotes are absolutely not appropriate. In general if your answer begins with 'I think', or 'I've heard', then it's not suitable for /r/AskScience.

If you would like to become a member of the AskScience panel, please refer to the information provided here.

Past AskAnythingWednesday posts can be found here. Ask away!

submitted by /u/AutoModerator
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Why does sunrise keep happening later in the morning for several days after the winter equinox (ie even though the length of the day is increasing)?

Posted: 09 Dec 2020 04:23 AM PST

If 2 neutral atoms are in a covalent bond, and both of them share one single pair of electrons, each atom will have more electrons than protons and should have a negative charge. Is that true? If not, how do they remain neutral even though the electrons would be more than protons in the atom?

Posted: 09 Dec 2020 01:05 AM PST

How do scientists genetically modify enzymes?

Posted: 09 Dec 2020 03:47 AM PST

If the space station was stationary and held up by thrusters or something, how much gravity would you experience on board?

Posted: 08 Dec 2020 11:11 PM PST

I've heard that the zero-g feeling is because it's in free fall, it's just going so fast that it basically just misses the earth. I also know that the further you are from earth the less gravity you experience. I'm just wondering how much gravity you would feel 400km/~250 miles up

submitted by /u/idrunkenlysignedup
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What vectors exists for contracting sicknesses like common colds, flu, coronavirus besides human transmission?

Posted: 08 Dec 2020 06:48 PM PST

How do a sender and receiver synchronize when communicatiing via a rolling code?

Posted: 09 Dec 2020 03:35 AM PST

If my car key uses a rolling code, how does it make sure the car keeps the current code in sync and actually expects the code I'm sending? Shouldn't it be the case that after I press my key several times while it is out of signal range of the car the key is ahead by several codes in the sequence and the car would no longer acknowledge the code?

submitted by /u/PattuX
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How do scientists make synthetic mRNA?

Posted: 08 Dec 2020 05:46 PM PST

I've seen several articles stating that the new COVID-19 vaccines are using synthetic mRNA. I was able to look up where mRNA normally comes from, but I can't find how scientists recreate it. (My science education in biology is limited to a high school class, so please keep that in mind as you answer.)

submitted by /u/Pegacorn21
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Is Deepmind's AlphaFold trained with a dataset of proteins and the 'correct' folding? If so, how do they get a big enough dataset?

Posted: 08 Dec 2020 04:01 PM PST

I don't know if anybody knows exactly how AlphaFold works on the inside but as I understand it (and I don't very well) it tries to predict the correct way a certain protein is folded. The deep learning I'm familiar with would suggest they have trained AlphaFold on a dataset with many of the problems and their solutions to check how close it is, which means they would need many proteins and their correct foldings. But isn't the problem they're trying to solve that right now it's very difficult to predict them? So how would they get a dataset like that if that's how it's trained?

submitted by /u/Snapsick
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Can one sample be used for both a CoVid-19 PCR test and a Antigen test?

Posted: 08 Dec 2020 06:10 PM PST

I just got a COVID 19 PCR test 2 hours ago, and I just got an email from the lab that my Antigen test was positive. I did not take an antigen test, I know it was a PCR as it looked just like the other PCR tests I have taken, and the tester told me they were out of antigen tests. Is it possible the lab ran an antigen test on the sample in the PCR test vial? Or was this an error on the tester's side.

submitted by /u/LostCausality
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With the rollout of the vaccine, how will kids/babies be protected if they're not eligible?

Posted: 08 Dec 2020 08:36 PM PST

If we send one photon againsta 50% transparent glass, what determines if it will pass through or if it will get reflected?

Posted: 09 Dec 2020 05:12 AM PST

How effective is Stage 1 of the Covid vaccine?

Posted: 08 Dec 2020 11:45 AM PST

This is not a question about the overall effectiveness of vaccines. I plan on getting the vaccine as soon as I'm allowed to. But how much protection will the first stage give me? Will I have to wait three months for the booster before I can hang out with friends again?

submitted by /u/questionthrowaway48
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With a DNA based vaccine, would blood donors also pass on the immunity to COVID to recipients?

Posted: 08 Dec 2020 07:31 PM PST

Passive immunity in the case where antibodies being shared with another person through blood transfusion are temporary as the recipient doesn't produce their own antibodies. But with the COVID vaccine being DNA based, would people who receive blood from another with acquired immunity ALSO become immune, or would it be another case of passive immunity?

submitted by /u/Online-Vagabond
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How do (coronavirus) mRNA vaccines function?

Posted: 08 Dec 2020 08:05 PM PST

The mRNA vaccine in the Pfizer vaccine codes for the spiky portion of the coronavirus particle. Your body recognizes it as mRNA and translates it to protein. At which point does your body know when to stop producing the pointy bits?

Do you just become one pointy boi at the end?

submitted by /u/Pina_Ka_Lada
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It appears that the death rate of the pandemic has decreased over time. Has the coronavirus pandemic become less deadly due to possible mutation, or has the medical response to it improved?

Posted: 08 Dec 2020 11:39 AM PST

Why do the M-RNA COVID-19 vaccines need to be kept cold if RNA exists just fine in our bodies?

Posted: 08 Dec 2020 06:25 PM PST

How do our planets stay in their orbits?

Posted: 08 Dec 2020 11:55 AM PST

So my very limited knowledge when it comes from science mostly comes from YouTube videos or shows I watch out of interest so please excuse me if I don't use any scientific technical terms. In addition English is not my first language so all I write might sound like utter nonsense.

So the planets and therefore also earth circle around the sun in orbits and the reason for that is how I very, very loosely and very possibly wrongly understood it:
That the universe is like some form of matter than can be influenced (bended) by great masses, like a stretched piece of cloth that would bend downwards if you put a heavy object in the middle making it like a funnel.
So the sun is that massive object that sits in the middle of the cloth that is our solar system bending it down making like a well or a funnel and the planets basically run around the wall of that "well".
(And I'm just realizing while writing how hard it is with my low knowledge trying to describe what I want to say.)
So if the sun is the most massive object and therefore being the center that pulls the matter of our solar system down, how does it work that our planets can stay in orbit and are not just slowly or quickly being pulled down towards the sun until they eventually collide with the sun?

I am very sorry if this is a stupid question?

submitted by /u/dontsaltmyfries
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Does the speed of sound change based on the force of what created the sound?

Posted: 08 Dec 2020 04:40 PM PST

I know the speed of sound changes depending on the density of the fluid it is moving through, but does it also change based on what creates the sound? i.e the sound of a gun going off vs. a pin dropping on a cement floor; would the soundwave of the round detonation be moving faster, slower, or the same speed as the soundwave of the pin given they happen in the same density of air?

submitted by /u/toomanyglobules
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Why don’t nuclear fuel bundles spontaneously undergo nuclear fission?

Posted: 08 Dec 2020 07:40 PM PST

As I understand it, a nuclear reactor starts when the control rods are raised. Neutrons are sometimes emitted from the radioactive isotopes in the fuel and if one strikes a fissile atom then a chain reaction is able to continue since the control rods aren't absorbing most of the neutrons.

So let's say you just have a fuel bundle sitting on the ground outside of a nuclear reactor with nothing absorbing any neutrons. Why wouldn't the fission process spontaneous start up and release a massive amount of energy to the surroundings?

submitted by /u/Trainbus6000
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