Why do some Israeli scientists say a second booster is "counterproductive," and may compromise the body’s ability to fight the virus? | AskScience Blog

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Friday, December 24, 2021

Why do some Israeli scientists say a second booster is "counterproductive," and may compromise the body’s ability to fight the virus?

Why do some Israeli scientists say a second booster is "counterproductive," and may compromise the body’s ability to fight the virus?


Why do some Israeli scientists say a second booster is "counterproductive," and may compromise the body’s ability to fight the virus?

Posted: 24 Dec 2021 08:13 AM PST

Israel recently approved a fourth dose for the vulnerable citing waning immunity after the first boost. Peter Hotez endorsed a second boost for healthcare workers in the LA Times. This excerpt confuses me though:

Article: https://archive.md/WCGDd

The proposal to give a fourth dose to those most at risk drew criticism from other scientists and medical professionals, who said it was premature and perhaps even counterproductive. Some experts have warned that too many shots eventually may lead to a sort of immune system fatigue, compromising the body's ability to fight the virus.

A few members of the advisory panel raised that concern with respect to the elderly, according to a written summary of the discussion obtained by The New York Times.

A few minutes googling didn't uncover anything. I'm concerned because I heard Osterholm mention (37:00) long covid may be the result of a compromised immune system. Could the fourth shot set the stage for reinfection and/or long term side effects? Or is it merely a wasted shot?

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In the rare occasion that someone gets myocarditis either from Covid or a vaccine, how long are they going to live? What is the life expectancy of someone with (not severe) myocarditis or pericarditis?

Posted: 24 Dec 2021 05:02 AM PST

Why does heterochromia seem to be so common in house cats, when compared to other kinds of pet animals?

Posted: 24 Dec 2021 08:53 AM PST

What is actually happening when someone's voice "cracks"?

Posted: 24 Dec 2021 09:22 AM PST

How long did people live 3,000 years ago? How do we know what was the average human life span/life expectancy back then? Can People Live to 150?

Posted: 24 Dec 2021 08:25 AM PST

If mRNA vaccines produce the spike protein within our cells and then our bodies produce antibodies to those proteins, why have some hospitals stopped using monoclonal antibodies to treat COVID-19? What’s the difference between our bodies’ antibodies and the monoclonal antibodies?

Posted: 24 Dec 2021 10:13 PM PST

What makes the vaccine antibodies more robust / diverse than the monoclonal antibodies produced in labs?

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Does toothpaste usage alter oral microbiome?

Posted: 24 Dec 2021 06:05 PM PST

I am unaware of papers that have tested the effect of brushing teeth with or without toothpaste on oral microbiome, but please let me know if there are any.

I would hypothesize that the toothpaste would alter the microbiome compared to no toothpaste brushing, as toothpaste is inherently bactericidal and probably temporarily alters the pH of the mouth? There are papers that look into different types of toothpaste on oral microbiome, but I'm not sure how trustworthy they are. The million dollar question would be if using toothpaste alter the oral microbiome for better or worse?

Edit: This paper is an interesting read on oral microbiome, does suggest the microbiome is important to tooth health, but still doesn't answer the questions at hand: https://www.nature.com/articles/sj.bdj.2018.81

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What geographical location has the most potential for simultaneous natural disasters? Earthquakes, volcanic eruptions, hurricanes, etc

Posted: 24 Dec 2021 08:37 PM PST

Is it possible to catch Covid again immediately having recovered from it?

Posted: 24 Dec 2021 04:39 AM PST

Say you've completed your 10 day quarantine and recovered from Covid.

If you were placed in a room with 5 infected people, would you get it again immediately?

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Do Covid variants "occur" all within one host person or do they likely occur across a group of people?

Posted: 24 Dec 2021 04:21 PM PST

Given the large number of variations in Omicron, I'm curious if it likely came about gradually across a group of people with new variations occurring as it's passed to new hosts or all variations likely occurred within one person?

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How long can COVID19 still be detected on a swab after the initial sample?

Posted: 24 Dec 2021 08:29 AM PST

What types of species (animal, plant, etc.) from the USA are invasive species to other countries?

Posted: 23 Dec 2021 06:15 PM PST

Do at home covid tests test specifically for covid-19 or just any coronavirus?

Posted: 23 Dec 2021 09:15 PM PST

Hi everyone, A friend and I were talking about the at home test for covid 19 and we were wondering if the test are specific to covid-19 or all Coronas in general. We are not scientist and when we did a google search could find a quick answer on reputable sites(like cdc and such). Thank you!!!

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Why aren't agonic lines simply the line drawn from magnetic north to polar north?

Posted: 23 Dec 2021 07:44 PM PST

I was watching a video about magnetic declination and the presenter was describing how there are lines of zero declination (called agonic lines), where you don't need to adjust a compass at all for it to point to true north. That makes sense to me, but when I got curious and looked up NOAA maps that show magnetic declination lines I saw that the agonic lines weren't where I expected them to be, and furthermore they didn't even form straight lines when projected on a globe. Here's a picture of the current magnetic north (as of 2020). If you drew a line through the north pole and the magnetic north pole, and extended it around the globe, it would touch Eastern Russia, and also just west of Greenland. Now here is a map of current declination lines. The weird projection they used makes it hard to visualize on a globe but what's very clear is that there's a big ol agonic line shooting right through the middle of the USA, and that line touches neither the north pole nor magnetic north. There's also a second agonic line that does go from the north pole to magnetic north, except rather than just going straight there it meanders through Africa first! What the heck? Why is this? Wouldn't people in Manitoba have to adjust their compasses quite a bit to point true north? Because according to the map they don't.

I don't know what concept I'm missing here but I'm hoping someone can help me out because this just makes no sense to me.

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If you've got plugged ears, does a high volume sound still damage the ears to the same degree, even if you can't hear the sound as much?

Posted: 23 Dec 2021 01:32 PM PST

This may seem stupid, but I had plugged ears (like from pressure changes) today while listening to music and became genuinely curious.

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How can we predict solar eclipses? And how were ancient people able to do so?

Posted: 23 Dec 2021 11:12 AM PST

Just something I've been wondering about for a while now...

As I understand it (Thanks, Bill Nye!), the orbit of the moon is "wobbly" and somewhat random. Given that information, how can we accurately predict solar eclipses months, years, and even decades in advance? Additionally, how were ancient peoples able to predict them as well without advanced scientific equipment?

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How did ancient economies work after banks were already invented but central banks didn't regulate economy and didn't set rates?

Posted: 23 Dec 2021 12:13 PM PST

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